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Tag: "active" at biology news

HIV mortality in India drops with introduction of generic antiretroviral therapy

...h lower rate in those receiving ART and its highly active drug counterpart, HAART. Accessible drugs have led, in part, to an 80 percent decline in HIV-related deaths in India between 1997 and 2003. Despite ART's importance in improving HIV-infected people's health, it can also cause problems. Adverse event...

Einstein scientists discover how protein crucial for motion is synthesised at the right place in the cell

...unters an enzyme, the protein kinase Src, which is active only in that part of the cell. Src adds a phosphate group to ZBP1 close to where it binds to messenger RNA, and this phosphorylation reaction detaches ZBP1 from the actin messenger RNA--unlocking the messenger RNA so it can now be translated into the...

Restoring silenced suppressor gene kills lung-cancer cells

...e days, the researchers found that cells having an active WWOX gene died off. The cells self-destructed through a natural process known as programmed cell death, or apoptosis. The lung-cancer cells that lacked the WWOX gene, on the other hand, continued growing and increased in number nearly five- or six-fo...

Wright bros. upstaged! Dinos invented biplanes

... tree-dwelling theropod dinosaurs to fully winged, active flyers, Chatterjee said. The central theme of the trees-down theory is that gravity was the source of energy: a small climbing dinosaur first parachuted down, then began to stay aloft longer by gliding, and finally acquired powered flight. As thos...

Prostate cancer uses Wnt signaling proteins to promote growth of bone tumors

...hen we altered the cells to increase the amount of active DKK-1, it blocked Wnt's signal, changing prostate cancer cells from an osteoblastic to a highly osteolytic cell line." To test their hypothesis, U-M scientists injected human prostate cancer cells into the tibias, or long leg bones, of one group of ...

Scientists discover the molecular switch for nerve cells' insulating jelly rolls

...showed that unmyelinated neurons do not possess an active neuregulin gene and that myelinated neurons do. In the first set of experiments, they transplanted unmyelinated axons from the peripheral nervous system (outside of the brain and spinal cord) of embryonic mice into laboratory dishes. They then added ...

NIAID researchers show how promising TB drug works

...m that the compound may be useful in treating both active and latent TB. (For information about the first clinical trial of PA-824, see June 14, 2005, NIAID press release: http://www3.niaid.nih.gov/news/newsreleases/2005/tb_pa_824.htm .) PA-824 must be chemically activated in the bacterium before it exert...

A new step towards an AIDS vaccine

...ted by anti-retroviral therapy. By identifying the active component of HIV-1 which stimulates pDC function, and consequently other antigen presenting cell function, the authors have recognized an important pathway whereby DC function can be targeted in the design of efficient vaccines or immunotherapies for...

Plants have a double line of defence

...But the researchers in Cologne have now shown that active immune responses make a key contribution to nonhost resistance ?for example, the transport of PEN2 to the place of infection. In further studies, the researchers hope to try to identify materials that are built up via PEN2 at the place of infection....

Researchers know what you were about to say; fMRI used to detect memory storage and retrieval

...nstrates that the same areas of the brain that are active during an event are activated when a person attempts to recall that event ?seconds before the memory surfaces. "This study shows that, as you search for memories of a particular event, your brain state progressively comes to resemble the state it w...

Max Planck researchers make a breakthrough in plant stem cell research

...m", and it contains totipotent stem cells that are active throughout the life of the plant. Unlike the stem cells of animals, which can only produce specific kinds of tissue after the animal is past its embryonic stage, plant stem cells remain their totipotency and, therefore plants can continue growing ove...

Machinery of the 'marijuana munchies'

Marijuana--or more specifically its active ingredient, tetrahydrocannabinol--has a well-documented tendency to stimulate hunger. And while scientists have traced this property to cannabinoid receptors in the brain, they have had little understanding of the neural circuitry underlying this eff...

Past experience of pheromones induces dominant courtship behavior in fruit flies

...se pheromones--the pheromones had to be carried by active adult males. The effect was so strong that males carried on exhibiting courtship dominance behavior until they were five days old. The authors of the study note that similar findings have been reported in mice and hamsters, suggesting that dominance...

Penn study finds direct role for glial cells in brain cross-talk

...was considered to be a support cell and to play no active role in regulating nerve impulse transmission. However, recent research by Haydon and other investigators has indicated that glial cells do produce chemical transmitters called gliotransmitters and that these chemical signals are recognized by the n...

Neurons generated in the adult brain learn to respond to novel stimuli

...ogy. It had long been believed that neurons, the active cells of the brain and nervous system, do not regenerate. Recent research has shown, however, that new cells are added to certain areas of the brain ?including those involved with memory and the sense of smell ?well into adulthood. Very recent work,...

Researchers show how air pollution can cause heart disease

...n important ingredient in plaque deposits and also active participants in a biochemical pathway related to inflammation. The study revealed several signs that this pathway was more active, strengthening the connection between airborne particles and cardiovascular disease. ...

Gene therapy potential for treatment of pancreatic cancer

...genetically modified virus, vasostatin was clearly active in the tissue. Tumour growth in the mice was also curbed, and when compared with mice which had not been infected with the virus, the difference between the two groups was highly significant. The researchers then looked more closely at the pancreati...

Jefferson researchers find nanoparticle shows promise in reducing radiation side effects

...genetically modified virus, vasostatin was clearly active in the tissue. Tumour growth in the mice was also curbed, and when compared with mice which had not been infected with the virus, the difference between the two groups was highly significant. The researchers then looked more closely at the pancreati...

How does Mycobacterium tuberculosis infect the lung?

...rld's population--are chronically infected without active symptoms. Nine million new cases of active disease are diagnosed annually, resulting in two million deaths. TB is predominantly a lung disease....

'Perception' gene tracked humanity's evolution, scientists say

...d, the human prodynorphin gene was 20 percent more active than the chimpanzee prodynorphin gene. Past research has also observed variation in expression levels within humans. This report supports a growing consensus among evolutionary anthropologists that hominid divergence from the other great apes was f...

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