Tag: "active" at biology news

Youth With HIV Take More Risks After New Meds Introduced

...te at the David Geffen School of Medicine. Highly active antiretroviral therapies, or HAART, were introduced in 1996. The new drugs have successfully lowered virus levels and prolonged the lives of thousands of HIV patients. Although the new study does not prove that the introduction of HAART is the cause...

Canada approves marijuana-based pain spray

...c relief of neuropathic pain in MS. Its principal active cannabinoid components are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). The ratio of THC to CBD in Sativex is 2.7 mg : 2.5 mg per spray, ensuring a standardized dose is delivered each time it is used. “The approval of Sativex is good ne...

Nanoparticle Breast Cancer Drug Approved by FDA

...s 100th the size of a red blood cell) in which the active chemotherapeutic drug, paclitaxel, is bound to a n...called albumin. By using this nanotechnology, the active component (paclitaxel) can be delivered into the body at a 50 percent higher dose over 30 minutes. ...

Mouse gene shows new mechanism behind cardiac infarction in man

...er degree of atherosclerosis, while mice with more active variants of the gene displayed the opposite. Studies of two patient groups revealed that a certain variant of the human homologue of the gene was more common in people who had a history of cardiac infarction than those without. “This is an example ...

Researchers discover underwater volcano

...ersity of California, San Diego, has discovered an active underwater volcano near the Samoan Island chain. During a research cruise to study the Samoan hot spot, scientists uncovered a submarine volcano growing in the summit crater of another larger underwater volcano, Vailulu'u. Researchers explored the u...

Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma

...cific growth-promoting gene called EWS-FLI1 that's active only in Ewing's sarcoma tumors. Once inside these cells, the genetic machinery of the tumor cells are effectively silenced or shut down, preventing further growth. "This is the first study to show that systemic administration of siRNA can inhibit d...

Biochemists report discovery of structure of major piece of telomerase; implications for cancer

...n most types of healthy cells in our bodies, it is active in the vast majority of cancer cells, Feigon said. Because cancer cells divide rapidly, their telomeres should get shorter more quickly than normal cells. However, because cancer cells have high levels of telomerase activity, which rebuilds the telo...

Marine sponge yields nanoscale secrets

...hetic molecules (that duplicate those found at the active center of the bio-catalyst of the marine sponge) onto the surfaces of gold nanoparticles. They showed that when two populations of these chemically modified nanoparticles, each bearing half of the catalytic site, are brought together, they function j...

Genetic therapy reverses nervous system damage in animal model of inherited human disease

...s for gene therapy because, as we show with LAMAN, active enzymes from genetically corrected cells will be secreted into brain tissue and taken up by neighboring cells, Wolfe said. "In this case we see that storage lesions throughout the brain had been greatly reduced, even though gene transfer was limited ...

One gene links newborn neurons with those that die in diseases such as Alzheimer's

...st neurons born during adulthood die, but a bird's active singing increases the survival rate of new neurons. They reasoned that, if UCHL1 levels are related to the death or survival of neurons, these levels should increase when birds are singing and when more new neurons thus have a chance of surviving. In...

Study reveals dramatic difference between breast cancers in US and Africa

...ion -- a measure of which genes were turned on and active -- in breast cancer tissue from 378 women in Nigeria and Senegal. They compared the results with a database of breast cancer tissue from 930 Canadian women compiled by Charles Perou and colleagues in North Carolina and British Columbia. They found t...

Compounds in plastic packaging act as environmental estrogens altering breast genes

...signed to see whether exposure to these hormonally active biological compounds could alter the genomic signatures of the mammary gland during critical stages of development." BPA (bisphenol A) is a synthetic resin used in food packaging, dental sealants and polycarbonate plastic products, which range from C...

Protein Discovery Could Unlock The Secret To Better TB Treatment

... TB bacteria in the body. Once the TB bacteria are active again, the disease becomes treatable using common drugs like antibiotics. Scientists believe that uncovering the molecular structure of this protein will lead the way to designing drugs which enable treatment of dormant and multidrug resistant TB. I...

Migratory songbirds have a specialized night-vision brain area

...s laboratory analyzed the brain structures for the active expression of two genes called ZENK and c-fos that...that the area, which they named Cluster N, was not active in the migratory birds during the daytime. Furthermore, non-migratory songbirds did not show strong ...

Doctors closer to using gene analysis to help trauma patients

... were able to consistently analyze which genes are active in patients with serious infections or traumatic injuries. Researchers want to understand the genetic features that enhance a patient’s recovery as well as the elements that cause people to die sometimes weeks after an injury occurs. Identifying tho...

Red delicious, Northern Spy apples have most antioxidants, chemists find

...oxidants in apples, but which polyphenols are most active in the fruit has perplexed scientists. Tsao and his colleagues used three different laboratory measures to evaluate polyphenol activity in apples that are popular in Canada: Red Delicious, McIntosh, Cortland, Northern Spy, Ida Red, Golden Delicious, ...

Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol

...terrupting spindle assembly - CDK will become more active in an attempt to correct the problem. Working with the Sysmex Corporation of Kobe, Japan, the researchers devised a test to measure CDK activity and the expression, simultaneously. They found that monitoring of two isotypes of CDK activity accurate...

Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer

...ed advanced breast cancer, as the agent is clearly active in this setting.?/p> An estimated 211,240 women will be diagnosed with breast cancer in the United States in 2005. Breast cancer is the most commonly diagnosed cancer in women and the second leading cause of cancer-related death in women in this ...

Supercomputers to focus brains on AIDS dilemma

...h a cyclic moiety, or "wing," to the "west" of the active center. Around this same time, the McCammon group...nd with their cyclic moieties to the "east" of the active center as well as to the "west." Based on these simulations, the researchers were also able to predi...

Gladstone investigators discover how resting T cells avoid HIV infection

...ther showed that blocking production of the small, active form of A3G in resting CD4 T cells was sufficient ...ion through the action of the small, enzymatically active form of A3G, which stops the virus in its tracks." CD4 T cells are a class of lymphocytes, or white...

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