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Tag: "active" at biology news

Gene Expression in the Aging Brain

...so the theory predicts that the most metabolically active tissues should show the greatest age-related reduc...eory of aging (namely, that the more metabolically active cortex should have a greater reduction in gene activity), this is the first demonstration that age-r...

Navigating the brain for sense of direction as paradigm for higher cognitive functions

...so the theory predicts that the most metabolically active tissues should show the greatest age-related reduc...eory of aging (namely, that the more metabolically active cortex should have a greater reduction in gene activity), this is the first demonstration that age-r...

Carnegie Mellon scientists create PNA molecule with potential to build nanodevices

...so the theory predicts that the most metabolically active tissues should show the greatest age-related reduc...eory of aging (namely, that the more metabolically active cortex should have a greater reduction in gene activity), this is the first demonstration that age-r...

Gene increases risk of tuberculosis

...netic change that increases the odds of developing active tuberculosis (TB). Pedro Flores-Villanueva and hi...7 was associated with increased risk of developing active tuberculosis, but the exact gene(s) responsible for this effect was not identified. Flores-Villanue...

Researchers show key protein necessary for normal development of red blood cells

... development, the embryonic epsilon-globin gene is active first, followed by the gamma-globin genes, and finally the adult form, beta-globin takes control following birth. Lloyd and Priyadarshi Basu, Ph.D., lead investigator at VCU, and the research team compared mice that were missing the gene for KLF2 to...

Marathon of nano-sprinters

...their diffusion, which is enhanced by motor-driven active transport. ...

Key brain regulatory gene shows evolution in humans

... of some 250 other candidate genes -- mainly those active in the brain -- that they are beginning to analyze for evidence of evolutionary selection. They plan to perform the same basic analyses, in which they compare sequence information between humans and non-human primates for signatures of evolutionary s...

Federal grant funds research on novel HIV therapy

...o substance P, a neurotransmitter long known to be active in the brain and nervous system. Dr. Douglas and colleagues discovered in 1997 that immune cells produce substance P and its receptor, neurokinin-1, and later showed that incubation with substance P raised HIV levels in immune cell cultures. They sub...

Limiting the damage in stroke

...etworks. Scientists knew that NF-kB signaling was active in neurons, but its function was unclear. "We had some evidence that in nerve cells, it could trigger a self-destruction program called apoptosis," says Markus Schwaninger of the University of Heidelberg, one of the heads of the project. "If that was...

Discovering the first steps in transcription-coupled repair

...ut transcription-coupled repair is defective. Thus active genes cannot be repaired preferentially. In XP patients, exposure to sunlight typically causes hyper-pigmented skin that is dry and parchment-like, and is followed by multiple skin cancers. If carefully shielded from ultraviolet light, for example b...

Brainstem blocks pain to protect key behaviors

...wave sleep. "OFF" cells, which suppress pain, are active during slow-wave sleep. Foo and Mason, who completed her post-doctoral training in Fields' laboratory, found that the pain-enhancing ON cells were inhibited and the pain-suppressing OFF cells were excited during feeding, results that duplicated the...

Tuberculosis still a risk for patients receiving HIV drugs

People taking highly active antiretroviral therapy (HAART) for HIV infection r...acquiring tuberculosis infection and of developing active tuberculosis within a short time, usually six months to one year," Dr. Girardi said. Since TB is a...

Bats use touch receptors on wings to fly, catch prey, study finds

...air flowing across the wing. These cells were most active when airflow ?particularly turbulent airflow ?stimulates the hair. When a bat's wing isn't properly angled or curved during flight, air passing next to the wing can become turbulent. Merkel cells help bats stay aerodynamically sound by alerting them ...

New methods offer insight into regulatory DNA

...ore than 630 genes were studied, of which 374 were active in the cell cultures. If gene activity in a cell culture was skewed from the average, it was investigated further. These genes were correlated with more than 750,000 SNPs ?sequence differences between individuals in the sample collection. A series o...

Johns Hopkins flu expert calls for mandatory vaccination of health care workers

...e. "It's now time to go the extra step, requiring active declination or even making vaccination a mandatory part of the job, linked to patient safety, along with such tasks as keeping hands clean and getting mandatory TB tests." Neither state nor federal law requires workers to provide medical details whe...

Researchers discover new form of cancer gene regulation

...e cell has on the gene for GLI1 can be present and active and the GLI1 is still not produced. Significantly, the study demonstrated that this regulation is conserved from human to the worm, Caenorhabditis elegans (often used in laboratory research), indicating that the formation of these RNA protein comple...

'Computer-chemistry' yields new insight into a puzzle of cell division

...," on the irregular molecular surfaces. Only when active sites and hot spots fit correctly can this brief d...ral topographies as well as the locations of their active sites. "But it was literally a guessing game trying to find which residues might be important in thi...

Needle-free immunizations

... the myriad shortcomings of injections have led to active research and development of needle-free methods of immunization. While most people prefer to avoid injections, the stakes are enormously higher than just helping people avoid a disagreeable prick of a needle. In third world countries, improper and ...

Scientists develop protein-sequence analysis tool

...gram consistently identified positions near enzyme active sites that had been previously predicted from stru... comparative sequence analysis to identify protein active sites, and have also used this knowledge to alter enzyme functions by switching particular amino aci...

Alleged 40,000-year-old human footprints in Mexico much, much older than thought

... deposited near a lake by volcanoes that are still active in the area around Puebla, Mexico. The so-called footprints, subsequently covered by more ash and inundated by lake waters, eventually turned to rock. But Paul Renne, director of the Berkeley Geochronology Center and an adjunct professor of earth an...

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