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Tag: "active" at biology news

Chemists create 'Superbowl' molecule; May lead to better health

...operties, Sherburn says. For instance, one highly active version of the superbowl molecule goes by the name tetrabromo-superbowl (C268H320O52Br4) due to the addition of four bromine atoms. The bromine atoms make the hole at the top of the molecule smaller, which makes it more difficult for things to pass i...

Man and mouse share genome structures

...oincided with the transcription starting points of active genes, as they and others had seen earlier in the yeast. Unexpectedly, they also found tags idling over regions near genes. The researchers think these sites have important regulatory functions, because the methylation patterns are similar in compara...

Protein discovery could unlock the secret to better TB treatment

... TB bacteria in the body. Once the TB bacteria are active again, the disease becomes treatable using common drugs like antibiotics. Scientists believe that uncovering the molecular structure of this protein will lead the way to designing drugs which enable treatment of dormant and multidrug resistant TB. I...

Fox Chase Cancer Center scientists identify immune-system mutation

...e show that when the normal form of this factor is active in all developing lymphocytes, it can redirect would-be killer cells to the CD4 helper T cell lineage. This indicates that Th-POK is a master regulator of the maturation process." Understanding the development of critical components of the immune sy...

Researchers Uncover Key Step In Manufacture of Memory Protein

... compartment, proBDNF is chemically converted into active mBDNF. After mBDNF is formed, it is released to th...not take place, proBDNF cannot be converted to its active form. Dr. Loh explained that the proBDNF molecule has four projections, resembling prongs. These pro...

Found: Missing sequence of the human Y chromosome

...chromosome. This sequencecontains eight putatively active genes that could be implicated insex-associated he...ilobase "euchromatic island" with eight presumably active genesflanked by repetitive satellite sequences.To ensure that this 554-kilobase sequence was in fact...

Marburg virus disease in Angola - update

...rting the Ministry of Health, Angola to strengthen active surveillance and contact tracing. Médecins sans Frontières (Belgium, France, Holland and Spain) are assisting with infection control and establishing isolation facilities in Uige hospital. Experts from the Department of Infectious Diseases, Manchest...

Gene therapy converts dead bone graft to new, living tissue

...matory tissue for differences in the levels of the active genes. He discovered that the genes that create two key proteins in living bone, called RANKL and VEGF, were barely expressed around the dead bone. He then modified a harmless virus to carry these genes, devised a method of freeze-drying a paste cont...

Jefferson Virologists Coax HIV Out of Hiding

...powerfulcocktail of anti-HIV drugs known as highly active antiretroviraltherapy (HAART), they hoped they had found a way to finally rid thebody of the virus. But they were wrong. The virus instead goes intohiding, dormant and practically undetectable in the body ?andimpervious to attack. While HAART manages...

Female sex hormones play a vital role in defense against sexually transmitted diseases

...ea is important because one in every four sexually active adults is seropositive for HSV-2 and women are much more susceptible than men. "The results directly indicate that the hormonal conditions that provide protection against primary exposure to sexually transmitted viral infections may be very differen...

Researchers identify target for cancer drugs

..., then we may be able to prevent Akt from becoming active and contributing to tumor formation." ...

Vital step in cellular migration described by UCSD medical researchers

...cell moves toward its intended target. If Rac were active throughout the cell, it would extend protrusions in all directions, in essence keeping the cell in one place. Until now, researchers have had limited understanding of the molecular mechanism that inhibits Rac activity in the back of the cell, to mai...

Study: Soap And Water Work Best In Ridding Hands Of Disease Viruses

...nd hygiene agents are now available with different active ingredients and application methods. "Our study showed that the anti-microbial hand washing agents were significantly more effective in reducing bacteria than the alcohol-based handrubs and waterless handwipes," he said. "Our study also showed that,...

Taking Aim With Nanoparticle PEBBLEs

...h targeted PEBBLEs, some rats were still alive and active two months later, and MRI images showed that their tumors had vanished. Kopelman and coworkers plan to tinker with the PEBBLEs a bit more before trying them on larger numbers of rats, and PEBBLE-based cancer treatments for people are a long way off....

Highly adaptable genome in gut bacterium key to intestinal health

...t 1,237 of the bacterium's 4,779 genes were highly active compared to B. theta grown in a simple-sugar soup. The predominant group of high-activity genes were involved in the acquisition and digestion of carbohydrates. "In mice fed complex carbohydrates, we found that the microbes attached to small food pa...

Why do insects stop 'breathing'? To avoid damage from too much oxygen, say researchers

...sect is active. For example, a grasshopper is most active when it flies. When the grasshopper is inactive and resting, however, it continues to breathe in oxygen at the same high volume it uses while flying. The result is excess internal oxygen that can cause oxidative damage -- the destruction of biomateri...

Jumping gene helps explain immune system's abilities

...chers show that a jumpinggene called Hermes, still active in the common house fly, createschanges in DNA very much like those created by the process behindantigen recognition."Hermes behaves more like the process used by the immune system torecognize a million different proteins, called antigens, than anypr...

UCSD Discovery Shows How Embryonic Stem Cells Perform 'Quality Control' Inspections

...chers show that a jumpinggene called Hermes, still active in the common house fly, createschanges in DNA very much like those created by the process behindantigen recognition."Hermes behaves more like the process used by the immune system torecognize a million different proteins, called antigens, than anypr...

New therapy for HIV/AIDS eliminates needles and excessive toxicity

...chers show that a jumpinggene called Hermes, still active in the common house fly, createschanges in DNA very much like those created by the process behindantigen recognition."Hermes behaves more like the process used by the immune system torecognize a million different proteins, called antigens, than anypr...

Gene sequencing explains bioremediation 'bug'

...chers show that a jumpinggene called Hermes, still active in the common house fly, createschanges in DNA very much like those created by the process behindantigen recognition."Hermes behaves more like the process used by the immune system torecognize a million different proteins, called antigens, than anypr...

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