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Tag: "actin" at biology news

Marathon of nano-sprinters

...ors move along microtubules and myosins move along actin filaments. The step sizes of these motors are of the order of 10 nm. By stepping in a directed fash-ion along filaments, the motors pull cargo particles which are much larger than the mo-tors themselves. In addition to their importance for the functi...

Einstein scientists discover how protein crucial for motion is synthesised at the right place in the cell

... The team's previous work showed how newly formed actin messenger RNA molecules find their way to the cell...'s periphery, the messenger RNA is translated into actin protein responsible for cell motility. This new study reveals another key role for ZBP1: Not only d...

Researchers learn how blood vessel cells cope with their pressure-packed job

... to the direction of stretch. "This orientation of actin fibers can be thought of as a feedback control in ...stretched only 1 percent of their length contained actin fibers with no directional orientation. However, as they increased the rhythmic stretching from 3 pe...

Anthrax stops body from fighting back, study shows

... Low doses of the lethal toxin stopped the protein actin from building filaments to steer the neutrophils, stopping the body's immune response, the study found. "Neutrophils crawl around in the body and roll around in the bloodvessels and whenever they sense bacteria, they gobble it up likePac-Man," said ...

Structures of marine toxins provide insight into their effectiveness as cancer drugs

...l masses grow faster than other cells in the body, actin provides an excellent target for drugs that could inhibit such rapid growth." Adds Allingham: "These marine toxins can knock out the lynchpins in these long chains or cap their ends and kill cancer cells. Moreover, initial work shows that even a l...

Spiders help scientists discover how muscles relax

...laments of another muscle protein, actin. When the actin and myosin filaments slide along one another, the ...d from the thick filament to connect with and move actin filaments during contraction of a muscle. The structural studies were done using tarantula striat...

Researchers develop assay that could be applied to drug screening

... the researchers showed how proteins linked to the actin framework of the cell are brought to sites of coat...force through polymerization. "The role played by actin in clathrin mediated endocytosis has been controversial for a long time," Zenisek said. "We've now s...

Scientists discover that host cell lipids facilitate bacterial movement

...s invades the body, it commandeers its host cell's actin cytoskeleton to invade other cells. In a report pu...r protein called ActA to stimulate the host cell's actin to form filaments at one end of the bacterium. "As these filaments lengthen, they drive the bacteri...

DNA Recombination and Repair—A New Twist to RecA Function

... to ferry intracellular cargo along fibers made of actin or tubulin proteins. The ATP-dependent assembly of actin or tubulin fibers itself can work as a motor: for instance, the march of white blood cells toward pa...

Plants, animals share molecular growth mechanisms

...ds to the creation of long protein strings, called actin filaments, that are necessary for cellular growth,...Cell. "Perhaps by learning about this pathway for actin filament formation, we can engineer plant cells to grow in different ways or alter how cells respond...

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