Achilles heel of the herpes virus possibly found
... useful for more than HSV drug treatment. It could act as a way to link vesicles containing drugs with cells, and deliver them inside". She is currently collaborating with U-M nanotechnology researchers on this concept. The findings suggest that B5 or its viral ligand could be a target for antiviral tre...Blink, and the brain misses it
...sonance imaging and could thus measure whether the act of blinking--independently of any change in light normally caused by eyelid closure--would influence the level of light-activated brain activity. The UCL scientists found that when volunteers were blinking, brain activity was suppressed in areas tha...To translate touch, the brain can quickly rearrange its sense of the body
...mation, the brain must perform a constant juggling act in order to make sense of the body and the world. In the new study, the research team used a method called tendon vibration to induce a distortion of healthy volunteers' sense of their own bodies. When the biceps tendon of the right arm was vibrated...Novel compounds show promise as safer, more potent insecticides
.... Many of the most widely used insecticides today act on only a handful of exploited targets, including the organophosphates, which block acetylcholinesterase, an enzyme that helps control nerve activity. Some experts are concerned that these older, less-selective insecticides could pose heath risks and...Study shows how retinoic acid enters a cell's nucleus
...ein, CRABP-II, gets into the nucleus, where it can act to suppress tumors." CRABP-II is a member of a gr... more efficiently, then you enhance its ability to act as an anti-carcinogen," says Noy. "It's a rapid transport advantage." Her findings emphasize the im...Scientists track stealth DNA elements in primate evolution
...tion rates. These hyperactive progeny elements may act as 'master' genes for the amplification of Alu subfamilies and are responsible for producing the majority of the subfamily members. Due to their high retrotransposition levels, however, they are likely to be rapidly purged from human populations thro...New lifespan extension genes found
...longer than normal. A third gene, Hst1, appears to act when both Sir2 and Hst2 are missing. Sir2 and the newly identified Hst genes account for all of the life-prolonging effects of caloric restriction in yeast, Lin said. In yeast, the effects of aging seem to be due to a build-up of toxic circular DNA...Thinking the pain away? Study shows the brain's painkillers may cause 'placebo effect'
...s heroin, morphine, methadone and anesthetics also act on the mu opioid receptor system to reduce pain. Because the endorphin system naturally tries to quell pain whenever it occurs, the researchers slowly increased the amount of concentrated salt water being injected in the muscle as the scans continu...Say what? Bacterial conversation stoppers
...o count their numbers and to get the population to act in unison. A synchronized group of bacteria can mimic the power of a multi-cellular organism, ready to face challenges too daunting for an individual microbe going it alone. Swelling populations trigger their quorum-sensing apparatuses, which have di...Endocannabinoids ?the brain's cannabis ?demonstrate novel modes of action to stress
...d psychological stress situations, stress hormones act on the brain to stimulate the release of endogenou...nnabinoids from neurons in the hypothalamus, which act as a local messenger within the hypothalamus to shut down the neuroendocrine stress response. One e...Promiscuous Catalytic Activity Possessed by Novel Enzyme Structure
...that give beer its bitter taste or in other plants act as sunscreens, pigments, or antibiotics ?to olivet...her previously known prenylation enzymes that only act on a small number of molecules, this new enzyme was able to attach prenyl groups to most of the diff...Stem cell training program to make its Stanford debut
...that give beer its bitter taste or in other plants act as sunscreens, pigments, or antibiotics ?to olivet...her previously known prenylation enzymes that only act on a small number of molecules, this new enzyme was able to attach prenyl groups to most of the diff...'Jumping genes' contribute to the uniqueness of individual brains
...bryonic brain, which mature into neurons, look and act more or less the same. Yet, these precursors ultimately give rise to a panoply of nerve cells that are enormously diverse in form and function and together form the brain. Identifying the mechanisms that lead to this diversification has been a longst...Fruit fly studies open new window on cancer research
...whether human equivalents of these fruit fly genes act in the same way. If they do, then new drugs or even dietary advice could block their activity and slow down the growth of tumours. This research tells us more about the way insulin works and so it is furthering our understanding of processes associat...A new molecule discovered in the battle between plants and disease
...olated a small protein called Pep1 that appears to act like a hormone, signaling to the rest of the plant to raise its defenses at the first sign of an infection. They also discovered the receptor protein to which Pep1 binds to exert its protective effects. Pep1 was isolated from the plant Arabidopsis t...New research could help us deliver genes for new bone formation
...iversity of Nottingham are developing scaffolds to act as a coating around the nanoscopic gene delivery systems. The scaffold controls the release of the gene delivery systems to generate the prolonged formation and development of bone tissue. The research teams are using the scaffold technology to deve...Structures of marine toxins provide insight into their effectiveness as cancer drugs
...h Pacific Ocean harbor toxins that potentially can act as powerful anti-cancer drugs, according to research findings from University of Wisconsin-Madison biochemists and their Italian colleagues. The research team has defined the structure of the toxins and provided a basic understanding that can be use...Engineered skin offers clues to melanoma development
... and p53 tumor suppressor pathways, which normally act to keep cell growth in check, as well as human telomerase reverse transcriptase (hTERT), the enzyme that protects the ends of chromosomes during cell division. This enzyme is associated with the progression of many cancers. None of these mutant genes...... and p53 tumor suppressor pathways, which normally act to keep cell growth in check, as well as human telomerase reverse transcriptase (hTERT), the enzyme that protects the ends of chromosomes during cell division. This enzyme is associated with the progression of many cancers. None of these mutant genes...Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance
... and p53 tumor suppressor pathways, which normally act to keep cell growth in check, as well as human telomerase reverse transcriptase (hTERT), the enzyme that protects the ends of chromosomes during cell division. This enzyme is associated with the progression of many cancers. None of these mutant genes...