International trial of two microbicides begins
...h laboratory and animal testing. It is believed to act by inhibiting the entry of HIV and other pathogens...d groups. One group will use BufferGel before each act of sexual intercourse, one group will use PRO 2000, one group will use a placebo gel, and the final ...MetaChip provides quick, efficient toxicity screening of potential drugs
...h laboratory and animal testing. It is believed to act by inhibiting the entry of HIV and other pathogens...d groups. One group will use BufferGel before each act of sexual intercourse, one group will use PRO 2000, one group will use a placebo gel, and the final ......es of varying size and structure may be created to act as carriers for drugs, genes and proteins. In addition, these porous nanoparticles can be used to host quantum dots and magnetic nanoparticles for bioimaging and quantum device applications. ...Falling ants glide back to trunk to avoid dangers of forest floor
... a mystery, but evidently claws on their back legs act like grappling hooks to snag the trunk and hang on... an unusual flattened head with flanges that could act as a rudder, Dudley said. "My guess is that, by gliding backwards and using their legs and also the...Programmable cells: Engineer turns bacteria into living computers
... send messages and other cells have the ability to act on these messages," said Weiss. The creation of patterns, such as the bull's-eye effect, is a key step in one of Weiss' eventual goals, which is to have the cells secrete materials that build physical devices such as antennas or transmitters in plac...Researchers devise way to mass-produce embryonic stem cells
... ?could not. "Cells grown on a flat surface don't act like they would in the body," Yang said. "The growing surface affects how a cell forms, what it looks like and even how it expresses genes." Cells grown in the bioreactor could grow for a much longer period of time than they could in the flask, as c...Flocking together: Study shows how animal groups find their way
... in a group; and the desire by some individuals to act on their own information about where to go. First, the researchers programmed their simulated animals with a basic urge to stay near others, but not collide with them. This instinct alone caused individuals to form close-knit, evenly spaced groups li...Polymers with copper show promise for implanted sensors
...nd, is copper. "It turns out that copper ions can act as catalysts to take nitrosothiols and generate nitric oxide from them," said Meyerhoff. So the U-M team has been creating polymers that include a copper ion-containing complex. They've demonstrated that complexed copper ions do have the desired cata...Advances in the characterisation of the oyster mushroom genes
...hin the cellulose molecule, the cellobiohydrolases act by liberating units of cellobiose from either end of the cellulose chain and the b-glucosidases hydrolyse the cellobiose molecules, producing glucose as end product. In her PhD thesis Arantza Eizmendi Goikoetxea has analysed the activity of one of t...Biodiversity hotspots identify conservation priorities
...l (CI) and co-editor of the new book. "We must now act decisively to avoid losing these irreplaceable storehouses of Earth's life forms." Nearly 400 specialists contributed to the four-year-long hotspots reappraisal. Their analysis has resulted in an increase in the number of hotspots from 25 to 34. The...50-year-old Mystery Solved: Protein Tags Regulate Key Ion Channel
... look and why we must go there. SUMO may very well act on other ion channels that have yet to reveal their function because they were silent like K2P1." Other membrane proteins key to biology, like transporters and hormone receptors, may also be controlled by SUMO since the binding site is present in th...Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection
...e. The abnormally folded protein itself appears to act as an infectious agent, transmitting disease without a DNA or RNA genome such as in a virus. Although disease prions seem to infect normal prions by binding to them and forcing them to take on the abnormal configuration, researchers remain uncertain ...Researchers report new pro-inflammatory role for anti-inflammatory enzyme
...of iNOS. "eNOS has until recently been thought to act principally in an anti-inflammatory manner," notes...sults of our study show clearly that eNOS can also act in a pro-inflammatory manner and accelerate host-defense in response to pathogenic stimuli." This d...Bioelectronic ‘signatures?hold key to DNA mutations
...nd nanotechnology to fashion nanocrystals that can act as “DNA biosensors?by electronically recognizing subtle mutations in the DNA. This creates enormous potential for applications such as the diagnosis and treatment of genetic diseases, detection of infectious agents and reliable forensic analysis. Wa...Researchers unlock mechanism creating jigsaw puzzle-like plant cells
... known as GTPases (guanosine triphosphatases) that act as molecular switches, which regulate how plant cells grow into interlocking patterns resembling jigsaw puzzle pieces. These proteins tell one part of a cell to grow outward while telling its neighbor to recede or indent itself in a finely tuned bio...Anammox bacteria produce nitrogen gas in oceans' snackbar
...cades, but by anammox bacteria. Nitrogen compounds act as fertilizers and are the ecological basis for any lifeform on earth as these compounds limit the overall growth rate. The researchers discovered this type of bacteria for the first time a few years ago in the oxygen poor Black Sea and now also in ...Researchers find promising cancer-fighting power of synthetic cell-signaling molecule
..., rather than just one." In essence, Enigmols may act like a multi-drug combination therapy, the investigators speculate. Enigmols are also being tested in combination with other cancer chemotherapeutic drugs using funds from EmTech Bio -- a life sciences technology business incubator operated by Georg...Edible bivalves as a source of human pathogens: signals between vibrios and the bivalve host.
...ing haemocytes and soluble haemolymph factors that act in a co-ordinate way to kill microorganisms. Our research examines available data on Vibrio interactions with both cellular and soluble components of the bivalve immune system in the light of the capacity of bacteria to evade the hemolymph bactericid...Biochemists report discovery of structure of major piece of telomerase; implications for cancer
...mall pieces of DNA on the ends of chromosomes that act as protective caps -- allowing DNA ends to be copi...ment. Every time a cell divides, telomeres, which act like the plastic tips on the ends of shoelaces, get shorter. In the natural aging process, the telom...Undesirable expatriates: Preventing the spread of invasive animals
...ased on plant invasions. Introduced animals do not act like introduced plants-- they appear to have a muc...te of invasion success. Once established, they can act as biological pollutants that result in ecological and economic damages. "The best way to combat inv...