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Tag: "acids" at biology news

Conserved amino acids play both structural and mechanistic roles in sandwich-like protein

The question of whether amino acids in sandwich-like proteins are there to stabilize t...h-like structure consisting of two sheets of amino acids meshed together. Nearly 70 superfamilies of proteins of varying makeup have this sandwich-like struc...

Biomarkers isolated from saliva successfully predict oral and breast cancer

...t hurdle stems from the fact that salivary nucleic acids or protein markers might be influenced by eating, drinking, smoking, diet or oral hygiene," said Wong. "So our goal is to provide the optimized and standardized protocol to assure consistent results." The studies are supported by grants from the U.S...

Disease diagnosis, biodefense among UH chemical research projects

...orption of nucleic acids." Purification of nucleic acids (DNA and RNA) is important in diagnosing genetic diseases, genome sequencing and making DNA-based vaccines for diseases like Ebola and HIV. ### For more information about the ACS meeting and to access a schedule of presenters and presentations, vis...

Researchers make gains in understanding antibiotic resistance

...on on messenger RNA into the long strings of amino acids called polypeptides that are used to build the cell's enzymatic machinery. "These antibiotics are clinically very important, and resistance to such antibiotics is a major health problem," said Steitz. "It is becoming critical to understand the preci...

Affymetrix Licenses Microfluidics Technology From Caliper Life Sciences

...he scope of the license agreement includes nucleic acids processing and handling associated with GeneChip arrays, but excludes the right to use LabChip technology with respect to products intended primarily to perform nucleic acid separations as a discrete, non-integrated quality control step. ...

Multi-purpose protein regulates new protein synthesis and immune cell development

...eas of the ER for processing. When too many amino acids pile up in the ER membrane, or when something goes wrong with the folding process, the entire system can get clogged with unfolded proteins. To prevent this, the cell activates the unfolded protein response (UPR). "The UPR has three main aspects," K...

McGill researchers shed light on formation of carcinogen in food

...ral and Food Chemistry, shows how food-based amino acids and sugars break down when heated to produce furan...uran and its derivatives sometimes form when amino acids or sugars are broken down by the heat of cooking," explains Dr. Yaylayan. "Normally, furan is a vola...

Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection

...n adopt, Weissman says. Species with similar amino acids sequences share an overlapping set of shapes, which helps explain why species with shared sequences have the ability to infect each other. Surewicz says the next step in their research will be to examine fibril shape differences at much higher resol...

LUCA technologies confirms real-time methane generation

...bic oxidation of hydrocarbons to alcohols, organic acids and carbon dioxide. Thermatoga also thrive in high temperature environments, such as those found in sub-surface oil wells. "Oil within the Monument Butte field has a waxy composition that may facilitate the strong real-time methane generation we see...

RNA project to create language for scientists worldwide

Research into ribonucleic acids (RNA)--the building blocks of life--is exploding as scientists worldwide discover the roles of RNA in genetics, health, disease and the development of organisms. The rapidly growing body of knowledge has created the need for researchers to develop a ...

PANTHER Protein Classification System Database 5.0

...g the Database is available freely in the Nucleic acids research Journal . AppliedBiosystems (NYSE:ABI), an Applera Corporation business, today announcedthe latest release of the PANTHER?system database of protein families,subfamilies, functions and pathways. Enhancements to the latestversion, Panther 5....

Amino acids in nectar enhance butterfly fecundity: A long awaited link

...peculations about the significance of nectar amino acids for butterfly fitness and insinuated that butterflies have acted as agents of natural selection on nectar composition. In order to determine whether butterflies actually need nectar amino acids, researchers from the University of Basel raised map b...

Researchers identify target for cancer drugs

...dding a phosphate group to a sequence of its amino acids (a process called "phosphorylation"). This process occurs not only in human cells but in other organisms such as the fruit fly. Finding this complex conserved in species as diverse as flies and humans supports the claim that the mTOR/rictor complex ...

A bacterial genome reveals new targets to combat infectious disease

...y its host. Conversely, it cannot synthesize amino acids and a variety of other vitamins and cofactors, and probably depends on the nematode to supply them. One discovery of possible significance is the presence in the bacterium of the synthetic pathway for heme - the oxygen-carrying iron component of hem...

Research advances quest for HIV-1 vaccine

...zes. The researchers identified the specific amino acids on gp41 that 4E10 interacts with and the 3D structure adopted by these amino acids. These study results suggest that 4E10 interacts with gp41 at a conserved region very close to the surface of the virus and they reveal some special characteristics of...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...ntial use in humans, the percentage of totalsialic acids present still ranged from 5 to 17 percent.Varki and his team noted that many efforts have been made during thelast few years to try to eliminate any animal-derived culturecomponents in human stem cell culture. However, many of the specializedmedia us...

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

...uming foods rich in saturated fats and trans-fatty acids causes elevated blood levels of cholesterol and tr...tunity to try to understand what makes these fatty acids so deleterious, and what we need to avoid." Moreover, it is possible that in the future, drug thera...

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