acids 2 7

Tag: "acids" at biology news

Female volunteers prepare for a second 'bedrest'

...accompanied by a dietary supplement (certain amino acids which form the basis of proteins). Volunteers needed for phase 2 For phase 2 of the study, which is due to begin in September, ESA, the French space agency CNES and the MEDES Institute are looking for twelve new female volunteers from the European ...

Redesigned protein accelerates blood clotting

...III has on its surface pocket-like chains of amino acids shaped to hold calcium ions (calcium binding sites). When calcium bonds to it, factor VIII changes shape and becomes better able to bind factor IX. In past research, Fay's team had identified a single amino acid (out of the more than 2,300 building ...

Fragment of yellow fever virus may hold key to safer vaccine

...dress on the envelope protein. Several other amino acids in another section of the folded protein contribut... essential epitope on one and the supporting amino acids on the other, ter Meulen speculates. The findings may apply to the whole flavivirus family. The res...

Study shows how retinoic acid enters a cell's nucleus

...I can only move into a cell's nucleus if its amino acids are organized in a certain sequence, called a nucl...artling discovery: When exposed to RA, three amino acids on the CRABP-II molecule flip their positions, exposing positive charges. Combined with the way the ...

Scientists at Galileo Pharmaceuticals confirm inflammatory response linked to glucose levels

...Kosik explained that proteins are strings of amino acids folded into small globs. All proteins that happen to be an enzyme involved in phosphorylation have one thing in common. They have a pocket that is almost always in the same place and this is where the phosphate attaches to the enzyme, in this case CD...

Scientists discover that three molecules may be developed into new Alzheimer's drugs

...Kosik explained that proteins are strings of amino acids folded into small globs. All proteins that happen to be an enzyme involved in phosphorylation have one thing in common. They have a pocket that is almost always in the same place and this is where the phosphate attaches to the enzyme, in this case CD...

Deep thinking: Scientists sequence a cold-loving marine microbe

...s cell membranes packed with polyunsaturated fatty acids that resist freezing, polyester compounds that off...ur to five genes to generate polyunsaturated fatty acids and pack those acids into cell membranes, resulting in membranes that are fluid and functional--rath...

Bacteria feed on smelly breath (and feet)

...ced from the breakdown of sulphur-containing amino acids in the mouth. Dr Ann Wood and her colleagues at Kings College, London, reported these findings in the August issue of Environmental Microbiology. The odour-eating methylotrophic bacteria were isolated from the tongue, tooth plaques (supra-gingival p...

MicroRNAs play a big part in gene regulation - and evolution

...o RNA molecules and then translated into the amino acids building blocks of proteins. But not all genes code for proteins--some make RNA molecules called microRNAs. These small RNA molecules interfere with--and therefore control--the production of proteins. A new paper in PLoS Computational Biology shows h...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

...ications are made from small molecules, like amino acids or lipids, and their permeability allows them to be absorbed from the intestine into the body," says Shen. "On the other hand, protein-based drugs are large and bulky, which can prevent them from crossing the intestine and gaining access to the sites...

Fat's fate depends on its source

...ne activated by fatty acids. "In short, all fatty acids are not created equal, at least in the liver," Semenkovich said. The findings suggest that products of fatty acid synthesis regulate glucose, lipid, and cholesterol metabolism by activating distinct pools of PPARa in the liver. Further study is requ...

The making and breaking of microtubules

...es like GTP are best known as units of the nucleic acids DNA and RNA, consisting of a base (a letter in the genetic code) plus a sugar and three phosphate groups. But these molecules also regulate enzyme activity and play a crucial role in controlling microtubule growth. When GTP binds to a particular loc...

Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine

...m different locales, 30 of the protein's 326 amino acids in hopes of eliminating the elements that suppress...and human macrophages, version rV10, missing amino acids 271 through 300, triggered only small amounts of IL-10 and had little effect on TNF secretion. Mice ...

Critical step traced in anthrax infection

...ntigen's pore-forming domain. Seven of these amino acids project into the lumen of the pore and form a collection of greasy residues, nicknamed "the phi-clamp" by the scientists. Because the water-filled lumen of the membrane pore is smaller than the folded lethal factor and edema factor, these proteins mu...

Life detection instrument passes key test on road to Mars

...ere able to detect the preference of Earth's amino acids for left-handedness over right-handedness. This "homochirality" is a hallmark of life that Mathies thinks is a critical test that must be done on Mars. "We feel that measuring homochirality - a prevalence of one type of handedness over another - wou...

Engineers improve plastic's potential for use in implants by linking it to biological material

...late that something contributed by the other amino acids in T59 influenced its 3-dimensional shape in a way that augmented its plastic preference. "This aspartic acid is just one piece of the puzzle," Sanghvi said. "There are still more pieces to put together." The researchers also evaluated how well T59 ...

Scientists analyze chromosomes 2 and 4

...uscle protein, called titin, which is 33,000 amino acids long. One of the central goals of the effort to analyze the human genome is the identification of all genes, which are generally defined as stretches of DNA that code for particular proteins. The new analysis confirmed the existence of 1,346 protein...

Microarrays as phenotype

...n researchers attach fluorescent labels to nucleic acids (DNA or RNA) from the cells under study. These labeled nucleic acids are allowed to bind to the DNA on the slides. Researchers then use a microscope to measure how much ...

Nature provides inspiration for important new adhesive

...s. Li's research group was able to add these amino acids to soy protein, and make it work like a mussel-protein adhesive. Then they began to develop other strong and water-resistant wood adhesives from renewable natural materials using mussel protein as a model. The research work has resulted in 11 papers ...

Affymetrix Launches New Globin-Reduction Kits and Protocol Developed with PreAnalytiX

...ection, stabilization, and purification of nucleic acids (DNA and RNA) for molecular diagnostic testing. The first product from PreAnalytiX, the PAXgene(TM) Blood RNA System, was launched in April 2001, and has set a new standard for stabilizing whole blood cellular RNA profiles at the time of blood collec...

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