acid 2 9

Tag: "acid" at biology news

Parallel evolution: Proteins do it, too

...ver the nutrients, such as protein and ribonucleic acid (RNA), a particularly important source of nitrogen...lar functional changes were due to identical amino acid changes at the protein sequence level," Zhang said. "Indeed, we found three amino acid changes that ...

Discovery could aid fight against cystic fibrosis infection

...nt chair John Mekalanos, recognized that the amino acid sequence of Hcp1 in PA closely resembled that of Hcp1 in Vibrio cholerae. The Mekalanos lab had previously discovered that the Hcp1 protein of V. cholerae is released from the bacterium via a novel secretion pathway. Because Hcp1 proteins from both ...

Mechanism for neurodenegerative diseases linked to transport proteins

...rt of a gene that encodes repetitions of the amino acid glutamine in the protein. Although different genes are affected, all of the polyglutamine-expansion or "polyQ" diseases are characterized by symptoms that begin in middle age and by the loss of certain types of neurons through a pattern in which the ...

Gene linked to rare disease activates fat breakdown

...e enzyme that specifically removes the first fatty acid from triglyceride. A third lipase finishes the job, Zechner said. The researchers now find that CGI-58 interacts with ATGL, stimulating its activity up to 20-fold. In contrast, CGI-58 variants with the mutations found in patients with CDS fail to a...

US infant mortality rate fails to improve

...rges women to take a multivitamin containing folic acid prior to and during early pregnancy to reduce the risk of serious birth defects; abstain from drinking alcohol during pregnancy and see their doctors to help manage chronic health conditions such as diabetes, hypertension and obesity. "Infant Mort...

Surprising symbiosis: Glassy-winged sharpshooter eats with friends

... essential ingredients? Yes. Realizing the amino acid pathways might be carried out by other bacteria li.... muelleri, the team found all the essential amino acid synthesis pathways. "When doing this type of forensic metagenomics, some scientists suggest you ca...

Stomach receptor for H. pylori discovered

...t University School of Medicine. "H. pylori alters acid production and can lead to increased acid outputs which causes peptic ulcer disease. The means through which H. pylori causes gastric cancer a...

Liquorice cancer care

...ealed that the liquorice compounds, glycerrhetinic acid and glycerrhizic acid, preferentially accumulate i...ned for the near future. In addition, glycerrhizic acid is tens of thousands of times cheaper and easier to isolate than the antibodies usually used. Tim ...

Acid rain causing decline in sugar maples, say researchers

... the research was conducted, suggests that because acid rain makes the soil more acidic, unfavorable condi...ecline of sugar maples is linked to the effects of acid rain produced by human activity, said Timothy Fahey, professor of forest ecology at Cornell and co-a...

Gene therapy prevents the onset of diabetic symptoms in mice

... the research was conducted, suggests that because acid rain makes the soil more acidic, unfavorable condi...ecline of sugar maples is linked to the effects of acid rain produced by human activity, said Timothy Fahey, professor of forest ecology at Cornell and co-a...

Gut reaction: Researchers define the colon's genome

... gut than researchers have reported for samples of acid mine drainage. These microbes are busy, too. The new study shows that resident microbes in the colon actively synthesize vitamins and break down plant sugars, such as xylan and cellobiose (similar to cellulose), which humans could not otherwise dige...

Test reveals effectiveness of potential Huntington's disease drugs

...itors to assess their protective ability. Folic acid has been suggested as a treatment for people with Huntington's because it interacts with homocysteine, a compound that makes nerve cells more vulnerable to glutamate. Gabapentin and lamotrigine, both glutamate inhibitors, are used in epilepsy treatme...

Finding the right mix: A biomaterial blend library

...r biomaterials. Polymers derived from the amino acid tyrosine make up a broad class of degradable biomaterials under investigation. Such materials provide a temporary scaffold for cells to grow and tissue to regenerate. In a 2006 study* presented at the national meeting of the American Chemical Society...

Scientists solve 30-year-old mystery of mutant mouse's kidney woes

...se pair had changed." The change swaps the amino acid serine for the amino acid leucine at a key position in the protein. Serine can undergo phosphorylation, a form of chemical mod...

Smoking changes brain chemistry

...ignificantly decreased concentrations of the amino acid N-acetylaspartate (NAA) in the anterior cingulate cortex (ACC), the part of the brain that processes pleasure and pain. The decreased NAA levels were evident regardless of whether or not the patient used a nicotine patch and correlated directly with ...

MIT creates 3-D scaffold for growing stem cells

...dding motifs With the addition of defined amino acid fragments called active motifs, the scaffold can be fashioned to coax stem cells to behave in certain desirable ways-such as differentiating into needed body tissues or migrating toward bone marrow and other natural destinations. "What makes these...

For super-obese patients, duodenal switch beats gastric bypass

... high blood pressure, elevated cholesterol levels, acid reflux, and obstructive sleep apnea in these patients. We don't know yet how much weight loss we need to get those health benefits, but losing more of the excess weight certainly seems to be better." ...

Jefferson scientists find aging gene also protects against prostate cancer development

...stell and his co-workers also found a single amino acid within the androgen receptor that reacts with SIRT1’s enzymatic activity and proved in the laboratory that it was key to its cancer-halting effect. The work could lead to a model for drug screening, Dr. Pestell notes. ...

Novel EGFR ectodomain mutations in glioblastoma

... missense mutations—changes that altered the amino acid sequence of EGFR. But the mutations were mostly different from the ones commonly seen in other cancers: rather than changing the kinase domain, most of the gliobastoma-associated mutations mapped to the extracellular domain of the protein. These fin...

How brain injury leads to seizures, memory problems

...n: the glutamate system and the gamma-aminobutyric acid system, abbreviated GABA(A). Glutamate stimulates neurons to fire, while GABA(A) inhibits that activity. "When lower levels of the KCC2 transporter weaken the dentate gyrus's ability to act as a gatekeeper," said Dr. Cohen, "neurons become more excit...

1 2 3 4 5 6 7 8 9 10