acid 2 5

Tag: "acid" at biology news

Prenatal exposure to marine toxin causes lasting damage

...d that the naturally occurring marine toxin domoic acid can cause subtle but lasting cognitive damage in r...toxin in animals after prenatal exposure to domoic acid levels below those generally deemed safe for adults, said Edward Levin, Ph.D. Those effects -- inclu...

A bug's life: Exceptional genomic stability yet rapid protein evolution in a carpenter ant mutualist

...he rate of protein evolution, as measured by amino acid changes, since the divergence of B. pennsylvanicus...g ancestors. The researchers showed that the amino acid sequences of Blochmannia have diverged approximately 50 times more quickly than proteins in free-liv...

Cornell finds natural selection in humans

...ns, positive selection causes changes in the amino acid sequence of the protein for which the gene codes. ...al goal of the project was to identify novel amino acid variants that could then be tested for association with human disease in subsequent studies. The Cor...

New antifreeze protein found in fleas may allow longer storage of transplant organs

...solated the new protein, which is rich in an amino acid called glycine. "When you grow a 'popsicle' of ice in the presence of these proteins, the AFPs bind to the ice and become included, while other proteins are excluded," says Dr. Davies. "We use their affinity for ice as a tool to purify the protein."...

Molecular cabal contributes to stroke damage

...in in the membranes of neurons. In response to the acid unleashed by ischemia, ASICs open to admit calcium... ASIC1a, to greatly enhance its sensitivity to the acid induced by ischemia. This increased sensitivity causes the ASIC channel to open and flood the neuron...

Anti-cancer drugs may hold promise for premature aging disorder

... hunch proved correct. When they changed one amino acid within progerin's farnesylation tag to prevent the addition of a farnesyl group and tested the effect in cells grown in the laboratory, progerin did not anchor itself to the inner nuclear membrane and instead clumped within the nucleus. Moreover, the...

Dangerous tricksters: Some bacterie use immune cells to reproduce

...t themselves comfartable in an environment free of acid and digestive enzymes and multiply there,' Professor Haas comments. Within a few days after the onset of the infection, the macrophages die of the infection, they disintegrate and release the multiplied pathogens. The Bonn cell biologists have demon...

Bacterial protein mimics host to cripple defenses

...). Abramovitch and Martin compared AvrPtoB's amino acid sequence to known proteins in other microbes and i... function is remarkable not only because its amino acid sequence is so different from other ubiquitin ligases, but also because bacteria don't use ubiquitin...

Katrina floodwaters not as toxic to humans as previously thought, study says

...w containing toxic levels of benzene, hydrochloric acid and chlorine. Instead, high levels of bacteria and viruses were the biggest human threat, not exposure to chemicals, Pardue and his associates say. The researchers obtained 38 floodwater samples from widespread sections of New Orleans, primarily in ...

SLU researchers uncover direct evidence on how HIV invades healthy cells

...n, reverse transcriptase, converts the ribonucleic acid (RNA) in HIV into deoxyribonucleic acid (DNA). Integrase then inserts the HIV DNA into the immune cell's DNA, making it a permanent part o...

Bugs expose underground carbon traffic system 10 times more important than fossil fuel burning

...ut Collembola for a particular phospholipid fatty acid (PLFA) that is characteristic for AM mycelia. They found that this particular PLFA contained significant amounts of 13C in cores not exposed to Collembola. However those soil cores that were exposed to collembola which fed on the mycorrhizal mycelia...

Yale participates in global human genome initiative

..., or compilation of short, interfering ribonucleic acid sequences. The library is designed to determine when individual genes are functioning. It uses a format that is accessible to researchers for detailed analysis of individual genes, gene families and metabolic pathways. The siRNA sequences have bluep...

Free-energy theory borne out in large-scale protein folding

...mics, scientists can use DNA to decipher the amino acid sequence in a protein. But knowing the sequence gives no clue to the protein's function, because function is inextricably tied to shape, and every protein self-assembles into its characteristic shape within seconds of being created. "The folded, fun...

Leading lampreys to slaughter: Pheromone for scourge of Great Lakes identified

...teroid and an already known, lamprey-specific bile acid derivative. Until the pheromone can be synthesized in bulk, extracts of water from larval lamprey nurseries are being used to trap adults on an experimental basis in Michigan streams. "Using these extracts has been shown to work," said Sorensen...

Jefferson scientists identify gene defect leading to abnormal skin development and cancer

...teroid and an already known, lamprey-specific bile acid derivative. Until the pheromone can be synthesized in bulk, extracts of water from larval lamprey nurseries are being used to trap adults on an experimental basis in Michigan streams. "Using these extracts has been shown to work," said Sorensen...

Image of myosin-actin interaction revealed in cover story of Molecular Cell

...ace is critical, evident by the way a single amino acid change in myosin leads to familial hypertrophic cardiomyopathy (FHC), an undetectable condition resulting in death by sudden cardiac arrest in otherwise healthy young adults. Contributors to this work include: Niels Volkmann, Ph.D., assistant profes...

What can change in the brain? Electrical synapses, research shows

... type of neural trigger that responds to the amino acid glutamate, a trans-mitter molecule in the brain. The result: a long-lasting, 20 to 30 percent reduction in electrical synapse strength. While previous studies have shown a related effect in the electrical synapses of goldfish, Landisman and Connors ...

New technique helps researchers determine amino-acid charge

... to predict protonation states -- whether an amino acid is charged or not. Appropriate experimental benchm...n affinity of an amino-acid residue when the amino acid is dissolved in a lot of water in, say, a glass beaker; another thing is the affinity for protons in...

Bacteria that cause tooth decay able to survive without important biochemical pathway

...he S. mutans population explodes, excreting lactic acid as it digests sugar. The acid makes life difficult for other helpful bacteria and demineralizes tooth enamel, causing decay. Acco...

Scientists show how thinking can harm brain cells

...odegenerative disease has been glutamate, an amino acid that normally acts as a neurotransmitter. Excess glutamate, however, can overly excite neurons, causing damage and death ?a process called excitotoxicity. Some drugs developed for the treatment of Alzheimer's disease, for example, are designed to low...

1 2 3 4 5 6 7 8 9 10