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Natural selection at single gene demonstrated

...e arisen and spread randomly. The scoring formula accounts for the greater similarity expected in related plants. Nordborg said that while natural selection is well documented at the whole-organism level, researchers consider biochemical proof of selection "the Holy Grail" of population genetics. "What ha...

Study in Science holds promise for a new approach to drug therapy

...as by Zantac and Claritin. Together the drug class accounts for $200 billion in annual sales. Authors of the current study believe they have found a new way to regulate the same GCPR pathways, but at different points. Where most drugs change the behavior of GPCRs on the outside of cells, the new class of dru...

Deep-rooted plants have much greater impact on climate than experts thought

...ccepted model of global climate, and found that it accounts for a previously observed but unexplained dip in Amazonian temperature during the dry season. "Evapotranspiration stays higher than previously expected during the prolonged dry season because of this private reserve of water banked during the wet se...

Scientists re-engineer a well-known antibiotic to counter drug resistance

...single atom change in the bacterial cell wall that accounts for the resistance. The results, Boger added, suggest that no matter how the VRE altered the cell wall component, it was still sensitive to treatment by the re-engineered vancomycin analogues. "The complex chemical synthesis of the glycopeptide a...

Landmark discovery of a Kaposi's sarcoma-associated herpesvirus receptor

...o is originally from Uganda where Kaposi's sarcoma accounts for at least 10 percent of known tumors. "Hopefully this will be the beginning of exciting new directions in this field, as it is likely to provide a useful framework for integration of the cell biology and epidemiology of this clinically important v...

UC Davis study finds HIV hiding from drugs in gut, preventing immune recovery

...cells is occurring. Gut-associated lymphoid tissue accounts for 70 percent of the body's immune system. Restoring its function is crucial to ridding the body of the virus." Results of the study suggest that patients being treated with antiretroviral therapy should be monitored using gut biopsies and that th...

One-third of adults with diabetes still don't know they have it

...issue of Diabetes Care, notes that type 2 diabetes accounts for up to 95 percent of all diabetes cases and virtually all undiagnosed diabetes cases. Diabetes is a group of diseases marked by high levels of blood glucose resulting from defects in insulin production, insulin action, or both. It is the most co...

Bt cotton in China fails to reap profit after seven years

..., China, India and Argentina, said Wang. Bt cotton accounts for 35 percent of cotton production worldwide. In China, more than 5 million farmers have planted Bt cotton; it is also widely planted in Mexico and South Africa. When U.S. farmers plant Bt crops, they, unlike farmers in China, are required by cont...

Researchers find cause of frontotemporal dementia

...frontal lobe is the foremost part of the brain and accounts for about 30% of the brain's mass. Among other things, the frontal lobe is involved in regulating behavior, movement and mood, and is responsible for cognitive functions like memory and speech. So, FTD is clinically characterized by changes in person...

Polynesia explorers created worldwide web of scientific knowledge

...cinated European public. "Their published travel accounts are the outcome of a system reaching across the gl...of Australia, Hawaii, New Zealand and Tahiti. Some accounts became bestsellers that "powerfully shaped the era's debates about the nature of human society." L...

WWF captures first-ever photo of wild rhino on Borneo

... in dense jungle where they are rarely seen, which accounts for the lack of any previous photographs of them in the wild. Conservationists hope that the population of at least 13 found last year is viable and will be able to reproduce if protected from poaching. A full-time rhino monitoring team, funded by ...

Snakes' virtual glasses, leopard spots and all-optical transistors

...are encouraged by the fact that their model easily accounts for the big cats' complex and changing patterns, and are hopeful that experimentalists will soon track morphogen chemicals down. An All-Optical Transistor Breakthrough G. A. Wurtz, R. Pollard, and A.V. Zayats Physical Review Letters (forthcomi...

Jellyfish dominate fish in over-harvested Namibian waters

...A. forskalea species), whereas the biomass of fish accounts for only 3.6 million metric tons. In their report, the authors point out that jellyfish biomass has risen in numerous locations worldwide, possibly as a consequence of fishing. Climactic changes could also contribute to jellyfish population shifts....

Mouse study reveals new clues about virulence of 1918 influenza virus

...8 flu virus genes interacting synergistically that accounts for the exceptional virulence of this virus. Michael G. Katze, Ph.D., of the University of Washington School of Medicine, Seattle, a grantee of the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Hea...

Combination therapy shows promising results in patients with advanced lung cancer

... of cancer-related death in both men and women and accounts for about 29 percent of all cancer deaths. This year alone, 174,470 people will be diagnosed with lung cancer in the United States. Of those, 162,460 will die, according to the American Cancer Society. Only about 15 percent of people who get lung ca...

Jefferson scientists identify gene mutation potentially involved in breast cancer initiation

...nt of estrogen-positive human breast cancer, which accounts for some 70 percent of all breast cancers. "This is the first demonstration that a specific Caveolin-1 mutation is exclusively connected to being estrogen-receptor positive," says Dr. Lisanti, noting that in tests of breast tumor samples, none of t...

UGA scientists unravel 'molecular inch-worm' structure of walking-pneumonia bacterium

...ns or make them far less severe. "M. pneumoniae accounts for 20 percent of community-acquired pneumonias in this country," said Krause. "Finding out more about how the bacterium that causes the disease works gives us a new edge in thinking of ways to overcome such infections." ...

A giant among minnows: Giant danio can keep growing

... the study, the researchers found that hyperplasia accounts for 67 percent of the giant danio’s muscle growth, compared to the zebrafish in which hyperplasia accounts for only 47 percent of the growth. Study: Phase II - Adult growth In the study’s second phase,...

Recurrence of a flu pandemic similar to infamous 1918 flu could kill 62 million

..., most historic information is based on eyewitness accounts and not on statistical analysis. Now, a team of researchers from Harvard School of Public Health (HSPH) and the University of Queensland in Australia have re-analyzed data from 27 countries around the world to estimate both the global mortality patte...

Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack

...s divided into four subcategories: ordinary (which accounts for about 90 percent of cases and has a fatality rate of about 30 percent), modified (which occurs in people who have been vaccinated and has a death rate of about 10 percent), and flat and hemorrhagic (both very rare and uniformly fatal). Accordi...

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