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Tag: "accessory" at biology news

New SARS Protein Linked To Important Cell Doorway

...es sought such sequences in portions of the virus' accessory genome—areas of its genetic code not commonly foun... to humans, researchers suspect a gene in the SARS accessory genome may be providing the virus with most of its pathogenic punch. Their computerized search high...

Scientists discover how Ebola virus infects cells

...nfectivity of Ebola virus dropped to near zero. An accessory role is played by another cellular enzyme, cathepsin L, the scientists determined. Inhibitors of cathepsins are already under clinical development as anti-cancer drugs. The authors write, "Further investigation of the antiviral efficacy of [enzyme] ...

The brain is broadly wired for reproduction

...ne information being conveyed by both the main and accessory systems," said Buck. "This redundancy is not too surprising, if you consider how important it is to the animal to be able to sense pheromones. The redundancy might guard against the loss of a pheromone receptor from either the VNO or the olfactory ep...

HIV accessory protein disables host immunity via receptor-protein intermediary

...lvania School of Medicine discovered that an HIV-1 accessory protein called Vpr destroys the host cell's ability to survive by binding to a host receptor. This, in turn, keeps an important enzyme from activating the cell's immune system. These findings refine an earlier understanding of Vpr HIV pathogenesis an...

Insects that produce males from unfertilized eggs reveal a surprising cellular feat

...cess involves enigmatic cellular structures called accessory nuclei, the function of which has not been explain...hat could give rise to new ones. We found that the accessory nuclei seed the formation of new centrosomes in unfertilized eggs," said Patrick Ferree, a graduate ...

Researchers now able to look deep into heart to view triggers of a heart's beat

...cess involves enigmatic cellular structures called accessory nuclei, the function of which has not been explain...hat could give rise to new ones. We found that the accessory nuclei seed the formation of new centrosomes in unfertilized eggs," said Patrick Ferree, a graduate ...

Cancer virus protein needed for successful infection

...ed p13. The protein is one of the virus' so-called accessory proteins, proteins that earlier studies done in la...t is important to understand the function of these accessory molecules so we know if they should be incorporated into vaccines or targeted by new drugs as a way ...

Unusual mechanism keeps repair protein accurate

...ith the help of so-called proof-reading regions or accessory molecules, this protein maintains its accuracy using an otherwise ordinary-looking portion of its molecular structure. The study was led by Zucai Suo, assistant professor of biochemistry and a researcher with the Ohio State University Comprehensiv...

Cellular traffic backups implicated in skeletal malformations

...ad expected mutations in proteins like collagen or accessory matrix proteins to cause craniofacial malformations. Realistically, nobody suspected that these so-called 'housekeeping genes' are responsible for that sort of phenotype." "For me, it's fascinating that the gene we have found was the least expected...

Protein overexpression at heart of heart failure

...A demonstrate an up-regulation of expression of an accessory subunit of the L-VDCC complex (beta 2-subunit) that is responsible for the altered channel behavior in human heart failure. Similar changes of both beta-subunit expression and single-channel behavior were also observed in a mouse model of heart failu...

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