Attacking cancer's sweet tooth is effective strategy against tumors
... more, they continue to use this pathway even when access to oxygen is restored. Though the so-called Warburg effect has since been confirmed, the role played by glycolysis in cancer has been largely ignored. Few have attempted to attack specific points along the glycolytic pathway to gain a therapeutic ef...What's shaped like a pear and has 2 genomes? Check the pond
...California-Santa Barbara. The team emphasized open access to data, providing the genome sequence data to out... Stanford University. The publication in the open access journal PLoS Biology represents a commitment to free and open access to scientific literature as wel...Newly identified protein complex sheds light on axon growth mechanism
... C.elegans. In a study published today in the open access journal Journal of Biology, researchers have characterised a new protein, UNC-69, required for proper locomotion . They show that UNC-69 interacts with UNC-76 in a protein complex likely to be involved in the trafficking of vesicles along axons - a p...Key to early diagnosis of autism may be in the placenta
...h scientist in the Yale Child Study Center who had access to many cases of children with ASD," said Kliman. "We realized that by working together we might be able to determine if this placental abnormality could be a useful clinical marker." With the help of Andrea Jacobs-Stannard, a student in Kliman's la...DOE JGI sequences, releases genome of symbiotic tree fungus
...on with other soil microbes and gains preferential access to carbohydrates within the plant. Such mycorrhizae are critical to terrestrial ecosystems, Martin said, since approximately 85 percent of all plant species, including trees, are dependent on such interactions to thrive. Mycorrhizae significantly i...Cigarette smoke blocks cell repair mechanism, University of Florida study shows
...ix their damaged DNA, many others become unable to access their own cellular first aid kit, according to findings from a UF study published today (Aug. 21) in the journal Oncogene. If they survive long enough to divide and multiply, they pass along their mutations, acquiring malignant properties. Past res...MIT 'seeing machine' offers hope to blind
...who are blind, or visually challenged like her, to access the Internet, view the face of a friend, "previsit" unfamiliar buildings and more. Recently the machine received positive feedback from 10 visually challenged people with a range of causes for their vision loss who tested it in a pilot clinical tria...Researchers develop flood-tolerant California rice
...ists beyond four days. Bailey-Serres notes that access today to information about the rice genome ?all the genetic material in the chromosomes of rice ?has greatly accelerated progress in identifying specific genes that confer specific traits. "Currently, the International Rice Research Institute is acti...Use of stone hammers sheds light on geographic patterns of chimpanzee tool use
...e stone hammers to crack open hard-shelled nuts to access the nutrient-rich seeds. The findings are significant because this nut-cracking behavior was previously known only in a distant chimpanzee population in extreme western Africa and was thought to be restricted by geographical boundaries that prevented...CHAVI announces international search for genes affecting HIV response
...ompeted to unravel the mysteries of HIV will share access to patient groups, called cohorts, they have studied. Support for the consortium is provided by the Center for HIV/AIDS Vaccine Immunology (CHAVI), established at Duke in 2005 with a grant that could total as much as $300 million over seven years fr...Impressive new Impact Factors for BioMed Central's open-access journals
...ven journals published by BioMed Central, the open access publisher, received their first Impact Factor this...als with a 2005 Impact Factor exceeding 3.00, open access journals are confirmed as publishing high-quality, highly cited research. Genome Biology, BioMed Ce...Scientists discover a genetic code for organizing DNA within the nucleus
...tant role in the cell's day to day function, since access to DNA wrapped in a nucleosome is blocked for many proteins, including those responsible for some of life's most basic processes. Among these barred proteins are factors that initiate DNA replication, transcription (the transfer of genetic informatio...New GI technologies improve internal organ visualization
...earchers are making the most of the opportunity to access new areas of internal organs that have not previou...gest that using a trans-esophageal process to gain access to the heart may be feasible and safe for patients as an alternative to the much longer, indirect ro...Life and death in the hippocampus: what young neurons need to survive
...t animals in an enriched environment and give them access to running wheels, you increase survival of new brain cells," says Gage. "Now we show that stimulation may, in part, be mediated through the NMDA receptor." Those studies had also shown that young and middle-aged "exercised" rats perform better on ...Molecular DNA switch found to be the same for all life
...s makes it difficult for these protein machines to access the DNA. Because of this complexity, the mechanism for initiating DNA replication in eukaryotes was presumed to be much different than the prokaryote initiator. Studies over the past decade have demonstrated that all of the multiple events that ...A new look at the state of the oceans
...n her field is the data base PLANKTON*NET. Free access to the plankton data base PLANKTON*NET is an onl...000 images and over 500 species descriptions. Free access to the data base enables all registered users to add their own images and data, and to supplement ex...Wild vs. lab rodent comparison supports hygiene hypothesis
... are consistent with the idea that animals without access to modern medicine have high levels of autoimmune-like and allergic-like immune responses that represent appropriate responses to unknown factors in their environment," he said. Although this study suggests that the environment plays an important ro...Vampire bats recognise their prey's breathing
... breathing. In a study published today in the open access journal BMC Biology, vampire bats of the species Desmodus rotondus could recognise recorded human breathing sounds much better than human participants could. Vampire bats feed on the same prey over several nights and the authors of the study propose ...Beekeepers work hard for the honey, despite changing tupelo forest
...economic factors play out to influence the use and access to tupelo forest." Some beekeepers say that every year they seem to be getting less honey for their efforts. Stallins and Watson will explore the degree to which changing river hydrology, exotic pests, land development and other factors are affecti......d an open question. But in a new study in the open access journal PLoS Biology, Kaori Shiojiri, Rika Ozawa, and Junji Takabayashi show that plant signals can indeed regulate herbivore behavior. When the larvae of beet armyworms ( Spodoptera exigua ) feed on corn, the plant releases volatile compounds that ...