Tag: "abnormalities" at biology news

Old memory traces in brain may trigger chronic pain

...sed by a single mechanism, Apkarian noted. Sensory abnormalities in people with chronic pain probably drive this memory abnormality. About 10 percent of the United States population suffers from chronic pain, of which the majority is back pain. One of Apkarian’s studies with rats tried to separately measure...

Brain holds clues to bipolar disorder

...(NIMH), suggests that bipolar disorder arises from abnormalities in neuronal plasticity cascades – the complex mach...roimaging, Dr. Phillips has identified patterns of abnormalities in the neural systems that underlie emotional processing and cognitive control unique to the bipolar...

Researchers reveal structure of protein altered in autism

...t this complex and contribute to the developmental abnormalities found in children with autism. Their work, publish...entists pinpoint the consequences of other genetic abnormalities associated with the disorder. “By understanding the three-dimensional structure of the normal prote...

First confirmed common genetic risk factors for breast cancer

...e, by helping cells to repair DNA breaks and other abnormalities that can result from chance or exposure to an environmental toxin, such as excessive UV sunlight. However, BRCA-1, BRCA-2 and the other previously identified breast cancer susceptibility genes are mutated in a relatively small percentage of women. ...

Gene malfunctions cause schizophrenia, depression symptoms in mice

...e of the mutant mouse strains exhibited behavioral abnormalities and memory deficiencies resembling the symptoms of...archers found. Also, both types showed biochemical abnormalities in the function of the protein produced by the DISC1 gene. The researchers concluded that the dif...

Study offers clues to 'Broken Heart Syndrome'

...nts, cardiac catheterization showed characteristic abnormalities in the motion of the heart. One patient died of acute heart failure. The good news is that most patients who survived the first 48 hours had a steady recovery. Thirty one, or 78 percent, of patients had follow-up echocardiography within a few wee...

Dinosaur hearing, listening to muscle noise, quieter cubicles

...ow physicians to identify cancer lesions and other abnormalities with higher sensitivity and specificity. Extensive tests of the VA imaging technique have been carried out at the Mayo Clinic. (3aBBa7) WORKPLACE SPEECH PRIVACY CALCULATOR Open-plan offices (cubicles) are here to stay. Construction trends c...

Brain maps online

...ers in identifying fine morphological and chemical abnormalities underlying Alzheimer's, Parkinson's and other neurological diseases, Mikula said. To make the maps, the researchers started with sections of brain mounted on microscope slides. Those slides were scanned to create image files or "virtual slides," ...

Gene found for rare disorder may reveal new pathway in mental retardation

...enes along the cohesin pathway also cause specific abnormalities during human development. "In these cohesin complex proteins, the strongest effect seems to be in brain development," said Dr. Krantz. Drs. Krantz and Jackson together maintain the world's largest database of patients with CdLS. The current study...

New player in commitment to life as a fat cell

...OR as a potential therapeutic target for metabolic abnormalities beyond hyperuricemia," the researchers said. "To our knowledge, there have not been studies designed to explore the effects of XOR inhibitors on body weight, and in light of our findings, such studies may be warranted," they added....

Researchers find gene mutation that causes infertility in male mice

...s. However, female carriers show higher rates of abnormalities during meiosis, which can potentially cause chromosome imbalances and birth defects, the researchers discovered. In addition, the researchers found that female mice with the Dmc1 mutation are born with fewer egg cells and can run out of eggs prematur...

Tumor-suppressor gene is critical for placenta development

...orators discovered that loss of the Rb gene caused abnormalities in the placenta, especially where it contacts the uterus. They published that research in the journal Nature. "This was the first evidence that Rb had an important role in the placenta," says Pamela Wenzel, a graduate student in Leone's laboratory...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

...sents a single variant among the different genomic abnormalities found among breast cancers. They measured molecular profiles of each cell line and used these to identify subsets of cell lines that represent the subtypes observed in analyses of primary tumors. By correlating the responses of these cells to ta...

Stanford scientists make major breakthrough in regenerative medicine

...evolutionary ancestor, the sea squirt, can correct abnormalities over a series of generations, suggesting that a similar regenerative process might be possible in people. "We hope the mechanisms underlying this phenomenon will ultimately lead to new insights regarding the potential of cells and tissues to be rep...

Chromosomal microarray analysis proves accurate

... microarray analysis to look for potential genetic abnormalities in children, they find that it is remarkably sensitive in detecting abnormalities in individual chromosomes, according to a report that appears online today in the journal Public Lib...

A potential biological cause for sudden infant death syndrome

...researchers at Children's Hospital Boston document abnormalities in the brainstem ?a part of the brain that regulat...instem, known as the medulla oblongata, they found abnormalities in nerve cells that make and use serotonin, one of over 100 chemicals in the brain that transmit mes...

T-ray breakthrough could make detecting disease far easier

...nd sensing of objects as varied as biological cell abnormalities and explosives has been announced. Researchers at the University of Bath, UK, and in Spain have said they have found a way to control the flow of terahertz radiation down a metal wire. Their findings are set out in a letter published in the current...

New gene linked to bipolar disorder

...e the role of the Slynar gene in the brain and how abnormalities in this gene may cause bipolar disorder. Using techniques such as animal models will help us to fully understand the mechanisms behind this gene and explore how we might be able to intervene in these mechanisms, to help people with the disorder. ...

Older fathers more likely to have autistic children

.... Autism is characterized by social and language abnormalities and repetitive patterns of behavior, according to .... Older parental age has previously been linked to abnormalities in the brain development of children; however, few studies have effectively examined the effect of m...

Diabetes slows nerve recovery after heart transplant

... understanding of the importance of nervous system abnormalities and an imaging technique to precisely characterize nerve damage may be of value to guide future therapeutic efforts aimed at reducing cardiac risk with diabetes mellitus patients," explained Bengel, who was an associate professor at the Technical Uni...

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