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Tag: "abnormal" at biology news

Can't serve an ace? Could be muscle fatigue

...r system diseases such as Parkinson's disease. The abnormal movements were likely to relate, in part, to a disturbed sense of effort, he said. ...

Tetanus toxin found to have therapeutic properties

...lly used as a therapy to treat disorders caused by abnormal muscular contractions such as strabismus, cerebral palsy, anal contractions and torticollis. Recently these toxins have been used even in cosmetics against wrinkles. For these therapeutic and cosmetic applications, the scientists are working with sub...

New clue to cocaine addicts' quirky behavior

...al plasticity. They found that the cocaine induced abnormal enhancement of neuronal connections--a phenomenon called long-term potentiation (LTP). The researchers also performed behavioral studies on the cocaine-sensitized rats, to explore the behavioral effects of this disruption. In these studies, they pla...

Snapin: A protein with therapy potential for autism

...other nerve cell or to the brain. When there is an abnormal decrease in dendrite branches, there are fewer sites to receive information and communication may be impeded. Individuals with disorders such as autism and Rett syndrome display not only fewer branches, but also show two quite different dendrite patt...

Pinpointing a culprit molecule in Alzheimer's disease

...e (AD) research is why mice engineered to have the abnormal protein underlying the disease in humans show little pathology of the disease. Specifically, such mice are genetically altered to overproduce mutant human amyloid precursor protein (APP). It is this protein that, when clipped by enzymes, produces the...

Researchers track down cause of a disfiguring bone disorder

... expression and are capable of leading to dramatic abnormal phenotypes (individual characteristics, such as diseases or defects) if altered or deleted." To investigate the misregulation of the SOST gene, Loots and her colleagues genetically engineered a copy of the DNA segment containing the gene and used it...

OHSU research shows vitamin C counteracts some negative impacts of smoking on unborn babies

...health impacts of smoking during pregnancy such as abnormal brain development and decreased body weight. The scientists also caution that more research is needed in regard to determining the appropriate vitamin C dosage for humans. Finally, studies need to be conducted to demonstrate that giving pregnant wome...

Pinpointing the cause of a neurodegenerative disorder

...rebellar ataxiaResearchers have discovered how the abnormal repetition of a genetic sequence can have disastro...a particular gene sequence to repeat itself. These abnormal genetic repeats cause the resulting proteins to contain unusually long repetitive stretches of the a...

Study: Harmless virus kills some cancers

...eve that AAV2 recognizes that the cancer cells are abnormal and destroys them. This suggests that AAV2 has great potential to be developed as an anti-cancer agent." The study was presented June 20, 2005, at the 24th annual meeting of the American Society for Virology held June 18-22 at Penn State, University...

New insights into how Huntington's disease attacks the brain

... first direct genetic evidence to demonstrate that abnormal interactions between cells can significantly contribute to brain cell death in a living mouse model of Huntington's disease," said Yang. Yang's team is now trying to pinpoint which of the neighboring cells generate Huntington's disease. "Our next s...

New defibrillator signals doctor of patient's irregular heartbeat or device malfunction

... heart back into a healthy rhythm if it detects an abnormal heartbeat. Irregular heartbeat (arrhythmia) is a major cause of death following heart attacks. Studies have shown mortality is lower in ICD-treated patients. "The new ICD provides faster delivery of care to patients and also reduces the nu...

To translate touch, the brain can quickly rearrange its sense of the body

...h and body position. The observations showed that abnormal input into one of the body's sensory systems produced a rapid and profound change in another sensory system: The brain had changed the way it interpreted the signals from the sense of touch. These links between different bodily senses show that the b...

High-powered gene profiles provide clues to genes involved in common form of lung cancer

...dy known to be involved in NSCLC reside within the abnormal regions identified by the Dana-Farber team. "This is compelling evidence that we're on the right track," says the study's other first author, Kwok-Kin Wong, MD, PhD, of Dana-Farber. "It's likely that the genetic mutations already linked to NSCLC con...

Survey reveals women and doctors aren't talking about HPV

.... The Pap test can identify cells that have become abnormal due to HPV, and HPV testing detects the presence of the virus itself. The FDA has approved routine HPV testing in women age 30 and older - the group most likely to have persistent infections and most at risk of cervical cancer. In addition, vaccines ...

Researchers test new therapy for advanced melanoma

... immune system to recognize the melanoma tumors as abnormal and attack. Eighty percent of the mice were cured with this therapy -- their tumors disappeared and the treated animals remained disease free for the full length of the study (100 days), Dr. Heller said. Furthermore, he said, even when melanoma cel...

Research into how prions act in the brain could hold the key to defeating diseases

... known what causes the proteins to develop in this abnormal way and it is not known how they kill nerve cells in the brain. Professor Hugh Perry and colleagues of the University's School of Biological Sciences are examining exactly what makes particular nerve cells in the brain more susceptible to attack by p...

15-year hunt finds cause of pseudothalidomide syndrome

...that the appearance and number of chromosomes were abnormal in people with Roberts syndrome, but we hadn't been able to figure out why or how," says Ethylin Jabs, M.D., a professor in the McKusick-Nathans Institute of Genetic Medicine at Johns Hopkins. "Just within the last few years have the genetic techniqu...

Researchers make surprise discovery that some neurons can transmit three signals at once

... to as ringing in the ears ?which can be caused by abnormal inhibitory signaling within the auditory system, a...tion. "It will be interesting to find out whether abnormal hearing, such as partial deafness or hearing dominated by noise, which in humans can affect normal l...

Report that delayed motherhood decreases life expectancy of mouse offspring

...ive effects of late maternal age in women, such as abnormal numbers of chromosomes in their children, are well known. However, other potential negative effects on offspring from delayed motherhood have been only anecdotal. In what the editors of Biology of Reproduction feel will be a controversial topic of d...

Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer

...roteinuria, a condition in which urine contains an abnormal amount of protein, than patients receiving paclitaxel alone. Other side effects were similar between the two treatment groups. Bevacizumab, a humanized monoclonal antibody** that already has been approved for metastatic colorectal cancer in combinat...

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