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Tag: "abnormal" at biology news

New cell type identified in cancer development

...e very complex. They have properties of normal and abnormal stem cells, and do not always lead to cancer ?only some of the time, and under very specific conditions," says Gao, who is also a member of the Ohio State University Comprehensive Cancer Center. "These cells appear to be a whole new class of cells i...

Scripps research study reveals structural dynamics of single prion molecules

...l folding mechanisms as well as those that lead to abnormal amyloid fibril conversion. The new insights may lead to the discovery of novel therapeutic targets for neurodegenerative diseases. Intriguingly, certain prions and amyloids can play beneficial roles. The subject of the new study, Sup35, enables prot...

Study to explore using magnets to correct 'sunken chest'

...ause heart and breathing difficulties, because the abnormal breast bone can reduce blood flow to the heart and prevent the lungs from expanding completely, restricting the ability to exercise, according to Harrison. Some patients also suffer serious emotional difficulties and low self-esteem, especially sinc...

Gene that makes people 'early to bed and early to rise' demystified

...ashion, meaning that it takes just one copy of the abnormal gene to exhibit symptoms. The UCSF group had earlier discovered a variant of the human Per2 gene that causes FASPS. They also showed that the so-called "S662G" variant, in which the serine building block normally present at position 662 is replaced...

Selective marker found to indicate aggressive form of breast cancer

...ndous amount of nestin, which likely represents an abnormal expansion of the basal epithelia." DiRenzo said. "If it is indeed specific to regenerative cells, then it will make for an excellent diagnostic tool for a cancer of regenerative mammary cells." According to the DiRenzo, another important next step...

Growth hormone is not the anti-aging bullet for healthy adults

..., joint pain, carpal tunnel syndrome, and, in men, abnormal breast development. They were also somewhat more likely to develop diabetes. The review, "The Safety and Efficacy of Growth Hormone in the Healthy Elderly," was published in the Jan. 16, 2007, issue of Annals of Internal Medicine and is availab...

Cancer researchers add spice to research against rare neuromuscular disease

...yielding in its progression. Both are caused by an abnormal repeat of three nucleotides, CAG, though not in th...uch diseases, the extra amino acids become part of abnormal proteins that clump up inside neurons, creating a clog that can bring normal molecular activity to a...

UCLA scientists design masks to hide genetic mutations from cell

...CLA scientists have devised a novel way to correct abnormal gene splicing ?a common mutation that often leads ...earchers designed a custom mask to camouflage each abnormal splice. The technique prevents the cell from seeing the genetic defects and restores splicing to th...

New test for most virulent HPV strains under study

...d significance ?pathologists call this most common abnormal result ASC-US ?or higher-grade abnormalities. “...d the other is as a triage test when women have an abnormal Pap smear result.? An HPV test typically follows an ASC-US Pap smear which at best, is about 80 pe...

Are scientists making progress in being able to regenerate bone tissue?

...dy can lead to post-operative pain, infection, and abnormal sensations at the removal site. An alternative is to use bone given by a donor—but such bone grafts from donors are less successful and there is a risk of transmitting viruses from the donor to the recipient. Given all these problems with bone gra...

Stanford scientists make major breakthrough in regenerative medicine

...e ultimate medical treatment would be to change an abnormal organ or tissue back to its vibrant, normal state," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "This study is a landmark in regenerative medicine; the Stanford group has accomplished the biological equivalent of turning a sow’...

Do you hear what i see?

...cessing, such as creativity and genius, as well as abnormal sensory processing, as seen in schizophrenia." Kayser notes that the findings also could be used to reveal the role of audio-visual integration in communication or to help pin down where sounds are coming from. "Clearly, our acoustical understandi...

New protein implicated in autism

...istics of individuals with autism. Importantly, an abnormal form of CADPS2 mRNA (which is an intermediate in the conversion of the CADPS2 gene to CADPS2 protein) was detected in some individuals with autism and was never detected in their healthy immediate relatives, leading to the suggestion that defects in ...

Brown team finds crucial protein role in deadly prion spread

...fatal brain diseases ?convert healthy protein into abnormal protein through an ultrafast process. This good-gone-bad conversion is one way that prions multiply and spread disease. But scientists believe that there is another crucial step in this propagation process ?fragmentation of existing prion complexe...

Widely used iron nanoparticles exhibit toxic effects on neuronal cells

...anoparticles were less well formed and also showed abnormal morphology and neurobiological characteristics. The researchers also studied long protein polymers inside the PC12 cells that make up the cytoskeletal structure. They found that iron oxide nanoparticles resulted in fewer and less organized microtu...

Temple University Hospital investigates treatment for cervical dysplasia

...lified participants must be 25 or younger, with an abnormal Pap test result in the past six months." Accord..." Every year, more than 3 million women have an abnormal result on a routine Pap test. Of these women, about 300,000-500,000 receive a diagnosis of moderate...

St. Jude announces breakthrough in eye cancer treatment

...toma. Apoptosis is the way the body rids itself of abnormal cells that might become cancerous or cause other problems. Until now, retinoblastoma experts thought that a mechanism called the p53 pathway triggered apoptosis in other types of cancer cells, but not in retinoblastoma. However, the St. Jude team p...

Gene key to taste bud development identified

...ophageal fistula, a condition in which there is an abnormal connection between the windpipe and throat that requires surgery for correction. Cancer patients receiving chemotherapy or radiation therapy often report the loss of taste during treatments. These therapies target cells that are dividing, making th...

New gene linked to bipolar disorder

...found in the brain, but in bipolar disorder has an abnormal effect due to mutations in the gene. However, researchers do not yet know what the gene's normal function is or how these mutations might be contributing to the disorder. Professor Hugh Gurling, UCL Department of Mental Health Sciences, says: "The...

Comprehensive model is first to map protein folding at atomic level

... work could help researchers better understand the abnormal protein aggregation underlying some devastating diseases, as well as how natural proteins evolved and how proteins recognize correct biochemical partners within living cells. The technique, which can track protein folding for some 10 microseconds --...

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