NIAID expands capability for influenza research and surveillance
...us becomes deadly, adapts and transmits infection; uncovering immune system mechanisms that protect against the H5N1 avian flu virus; and identifying the factors that make animals and people susceptible to flu virus infection. In addition, St. Jude will expand its animal surveillance to more than a dozen countr......ngered species will guarantee that we can continue uncovering new facets of our past. Relevant finds come from all parts of the African continent, including the rainforest, and not just the classical east African homeland. ...Erectile dysfunction in diabetes is due to selective defect in the brain
...eracts with diabetes. The study is another step in uncovering the link between the two disorders, and may lead to improved efficacy in treatments. The study, "Lack of Central Nitric Oxide Triggers Erectile Dysfunction in Diabetes," was conducted by Hong Zheng, William G. Mayhan, and Kaushik P. Patel, Departme...International team analyzes human genetic variation in key immune region
... scientific foundation for future efforts aimed at uncovering the genetic roots of immune-related diseases. The findings of this international team, which includes scientists from the Montreal Heart Institute (MHI), the Université de Montréal (UdeM), the Broad Institute of MIT and Harvard and several other rese...New roles for growth factors: Enticing nerve cells to muscles
...ssion Laboratory, "but that piece by piece, we are uncovering general principles that ensure that the developing nervous system establishes proper neuronal connections." Understanding how axons find their destinations may help restore movement in people following spinal cord injury, or those with motor neuron...New approach to vaccine development provides potent, long-lasting immunity
...admehr. As a next step, the team is interested in uncovering which parts of the brain are responsible for slow-learning. They hope that teasing this system apart will not only improve the understanding of brain function, but also tailor therapy strategies to target slow-learning and increase recovery of muscle...Robotic joystick reveals how brain controls movement
...admehr. As a next step, the team is interested in uncovering which parts of the brain are responsible for slow-learning. They hope that teasing this system apart will not only improve the understanding of brain function, but also tailor therapy strategies to target slow-learning and increase recovery of muscle...Cuttlefish masters of disguise despite colorblindness
...r colleagues suspect might be a critical factor in uncovering what determines camouflage patterning in cuttlefish. Despite these results, the vexing question of how cuttlefish master the task of camouflage in low-contrast, color-rich environments such as those found at shallow depths of water, remains to be an...Earth Rx: A microbial biotechnology prescription for global environmental health
...ts on the ocean's floor to arctic permafrost. Now, uncovering and categorizing this abundant biodiversity is one of the chief goals of scientists in the field of microbial ecology ?and may be the key to helping the planet –by putting these rich microbial communities to work to help serve the needs of society th...The world's deepest dinosaur finding - 2256 metres below the seabed
...egians found one using a drill. The somewhat rough uncovering of Norway's first dinosaur happened in the North Sea, at an entire 2256 metres below the seabed. It had been there for nearly 200 million years, ever since the time the North Sea wasn't a sea at all, but an enormous alluvial plane. It is merely a co...MIT: Oceans are a major gene swap-meet for plankton
...search, led by MIT Professor Sally W. Chisholm, is uncovering a challenging new facet of evolution, helping scientists see how photosynthesizing microbes manage to exploit changing conditions such as altered light, temperature and nutrients. The work will be reported in two articles in the March 24 issue of S...Marine mammals are on the frontline of failing ocean health
...ding scientists, physicians, and veterinarians are uncovering new links between land-based pollution and diseases in marine mammals, with implications for human health. "Marine mammals are providing early clues of our unseen impact on the sea," says Paul Sandifer, Chief Scientist for the new Oceans and Human H...Boosting newborns' immune responses
...r bio-terrorist threat, Levy adds. Levy's team is uncovering other differences between the newborn and adult immune systems that could lead to additional targets for drugs or vaccines. A related paper, to be published soon in the journal Pediatric Research, finds that when newborns' TLRs are stimulated during ...Scientists discover interplay between genes and viruses in tiny ocean plankton
...achusetts Institute of Technology, the research is uncovering a new facet of evolution and helping scientists see how microbes exploit changing conditions, such as altered light, temperature and nutrients. "These results tell us that even the smallest organisms show genetic variation related to the environment...'Dating agency' boosts hunt for disease genes
...and data infrastructure to tackle the challenge of uncovering the genetic pathways of complex disease." Dr Kate Dixon, who manages the archive at the Centre for Integrated Genomic Medical Research (CIGMR) at The University of Manchester, adds: "The archive manages tens of thousands of samples for a dozen dise...RNA splicing occurs in nerve-cell dendrites
...ed to only take place in the nucleus of cells. By uncovering this capability in dendrites, the investigators hope to relate this capacity to memory and learning, as well as cognitive dysfunction. Senior author James Eberwine, PhD, Professor of Pharmacology, and lead authors Kevin Miyashiro, and Jason Glanzer, ...Science's Breakthrough of the Year: Watching evolution in action
...er dreamed that researchers in 2005 would still be uncovering new details about the nuts and bolts of his theory -- how does evolution actually work in the world of influenza genes and chimpanzee genes and stickleback fish armor? Studies that follow evolution in action claim top honors as the Breakthrough of th...... of inhibitory circuits of neurons, and now we are uncovering how these specialized nerve cells work together and with other neurons," Callaway explained. "By understanding the brain in finer and finer resolution, we can then trace what happens when these neural circuits are mis-wired," he added. The Nature N...A bug's life: Exceptional genomic stability yet rapid protein evolution in a carpenter ant mutualist
...es of symbiotic microbes, scientists are currently uncovering the biological and mechanistic basis for these mutualistic associations. One of the primary genomic characteristics of obligate bacterial symbionts is a massive reduction in genome size compared to their free-living counterparts ?a phenomenon called ...NHGRI expands effort to revolutionize sequencing technologies
...m leap in the scope and scale of research aimed at uncovering the genomic contributions to common diseases, such as cancer, heart disease and diabetes." Over the past decade, DNA sequencing costs have fallen more than 50-fold, fueled in large part by tools, technologies and process improvements developed as pa...