Newly Discovered Compound Blocks Known Cancer-Causing Protein
...on in the cell, from where it can send signals for unchecked growth. "Ras needs to be at the plasma membrane in order to function," he said. "By preventing Icmt from adding a methyl group, we can effectively shut down Ras' ability to function, stopping it from sending signals for uncontrolled growth." Initia...Improving the potential of cancer vaccines
... diseases will result because the immune system is unchecked and goes on to attack the body's own tissues. His group previously reported the existence of tumor-specific Treg cells at tumor sites. "Thus, the tumor cells use these Treg cells to protect themselves," said Wang. "In fact, tumor cells can actively ...MBL researchers probe how an ancient microbe thrives and evolves without sex
...l reproduction compensates for, but which often go unchecked and are believed to contribute to mutation (and eventually extinction) in species that reproduce asexually. To learn more about the bdelloid rotifers' unique ability to evolve without sex, Arkhipova and Meselson studied portions of different bdelloi...Report focuses on challenges to unlocking future promise of vaccines
... been profound. Many diseases that formerly raged unchecked are now under control and others have been eliminated in parts of the world. Despite this success, infectious diseases continue to be public health problems particularly in developing countries where vaccines are unavailable, unaffordable, or both,"...Liver cancer linked to cellular repair pathway
The unchecked activity of a cell signaling pathway crucial in embryonic development and the liver's response to injury leads to liver cancer, researchers from Duke University Medical Center and John Hopkins University School of Medicine have found. Because the pa...World faces challenge as life expectancies lengthen, scientist says
... If anti-aging technologies are distributed in the unchecked free market, "it's entirely likely to me that we'll wind up with permanent global underclasses, countries that will get locked into today's mortality conditions," Tuljapurkar said. As the gap widens and rich countries continue to invest in anti-aging...Researchers reveal lung's unique innate immune system
...inimize collateral damage to lung tissue caused by unchecked inflammation," said Eyal Raz, M.D., Professor of Medicine at UCSD School of Medicine. The body's respiratory tract is constantly exposed to inhaled particles or microorganisms. The alveola ?tiny air sacs in the lung where exchanges of gases betwee...Groovy protein essential for promoting cancer development
...enzyme whose excessive activity contributes to the unchecked growth of as many as 90 percent of human tumors. The enzyme is vital for some rapidly dividing cells ?such as those in a developing embryo ? where it extends telomeres, the regions of highly repetitive DNA found at the ends of chromosomes. In most he...Report lists top 20 most-vulnerable African carnivores
...enzyme whose excessive activity contributes to the unchecked growth of as many as 90 percent of human tumors. The enzyme is vital for some rapidly dividing cells ?such as those in a developing embryo ? where it extends telomeres, the regions of highly repetitive DNA found at the ends of chromosomes. In most he...Speeding discovery of the 'human cancer genome'
...lly contribute to the cancerous cells' ability for unchecked proliferation or spread. Simply sorting through those differences one by one takes time and money, said Lynda Chin of the Dana-Farber Cancer Institute and Harvard Medical School. "There has to be a way to prioritize the effort," she said. C...Researchers image molecular motor structural changes
...ing how motors work in cancer cells, which undergo unchecked cellular division, might lead to new anticancer therapies. The team, from Duke University Medical Center, the National Institute of Advanced Industrial Science and Technology in Japan, and the Medical Research Council's Laboratory of Molecular Biolo...Brown cancer biologists identify major player in cell growth
...cer. Since a key characteristic of cancer cells is unchecked growth, the research identifies potential targets for new treatments. "As a scientist and a physician, I am tremendously excited," said Alan Rosmarin, M.D., an associate professor in the Department of Medicine and the Department of Molecular Biolo...Researchers find 24 species believed new to science in Suriname rainforest
...eventing fragmentation of the natural habitat from unchecked or poorly planned development. The Guayana Shield region contains the largest undisturbed tropical rainforest on the planet, a northern Amazon tract three times larger than the U.S. state of Texas (twice the size of Ethiopia) that is home to 100 i...