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Tag: "tagging" at biology news

Color-blind method opens new doors in DNA sequencing

...ach corresponding to a particular nucleotide. This tagging process, called Sanger sequencing, results in smaller DNA fragments, which are then separated base-by-base. Because the DNA fragments are tagged with dyes, they glow when they are struck by laser light to determine the order of one's DNA sequence. M...

Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells

...requires a time-consuming process like fluorescent tagging or a chemical reagent. We've found we can see them immediately by light alone." The techniques could be critical to advancing early detection, diagnosis, and treatment of disease. More technically put, "To rapidly assess the health of a single mamm...

Bioelectronic ‘signatures?hold key to DNA mutations

...the approach is the combination of the nanocrystal tagging of DNA to create electro-diverse signatures and combining them with a fast, portable, low-cost electronic detection,?Wang says. To achieve the desired results, Wang and his researchers custom-made several individual nanocrystals, known as quantum do...

Virginia Tech group adds tools to DNA-targeted anti-cancer drugs

... and Brewer. And Zigler will present "Luminescence tagging of 2,2'-bipyridine complexes of Fe(II): Synthesis and metal binding studies of 4-[N-(2-anthryl)amido]-4'-methyl-2,2'-bipyridine" (INOR 141), co-authored by graduate students Mark Elvington and Jared Brown and Brewer. At the SciMix poster session fr...

Bad aftertaste? New sensory on/off switch may 'cure' bane of artificial sweetener search

... and Brewer. And Zigler will present "Luminescence tagging of 2,2'-bipyridine complexes of Fe(II): Synthesis and metal binding studies of 4-[N-(2-anthryl)amido]-4'-methyl-2,2'-bipyridine" (INOR 141), co-authored by graduate students Mark Elvington and Jared Brown and Brewer. At the SciMix poster session fr...

Tagging pathogens with synthetic DNA 'barcodes'

..., illegal drugs and other chemicals of interest by tagging them with color-coded probes made out of synthetic...conventional bar codes. Since then, most molecular tagging devices have been referred to as "barcodes," even though there are no bars involved. The researcher...

Nanoscale method for investigating living systems

...biomedical applications ranging from intracellular tagging of molecules to applications such as tracking devi... Wisconsin engineering team set out to use optical tagging or labeling of membrane pores in order to visualize their function and simultaneously measure their ...

Carbon nanotube absorption measured in worms, cancer cells

...t had no way to determine how much was there." In tagging the nanotubes with the isotope, researchers found that about 74 percent of the nanotubes added to a culture of cancer cells were assimilated by the cells after 15 minutes, and 89 percent of nanotubes assimilated after six hours, according to the pape...

High-tech tags on marine animals yield valuable data for biologists and oceanographers

... and other researchers will present the results of tagging studies involving California sea lions, northern e...als during the Antarctic winters of 2001 and 2002, tagging 34 seals and tracking their foraging patterns. Crabeater seals are specialized for feeding on Antarc...

Clock molecule's sensitivity to lithium sheds light on bipolar disorder

..." says Lazar. Lithium blocks this action of GSK3, tagging Rev-erb for destruction, which leads to activation of clock genes such as bmal1. "We suggest that just as our cells in the incubator need to have their internal clocks reset, maybe this is what happens in some people with circadian disorders," says L...

New technology used to construct the first map of structural variation in the human genome

...rative genomic hybridization (CGH), which involves tagging genomic DNA from two individuals and then co-hybridizing it to the array. Data from the array were assessed with a new algorithmic tool, called CNVfinder, which accurately and reliably identified CNVs in the human genome. "This method helped us t...

Biofuel cells without the bio cells

...f scientist and co-author Uljana Mayer devised new tagging methods that enabled the team to isolate sufficient amounts of protein. The tags also allowed fast measurements of protein-mineral binding. The researchers supplied the protein with energy--directly as electrons or in the form of a natural cellula...

Key to lung cancer chemo resistance revealed

...ns manufactured by KEAP1 bind to the NRF2 triggers tagging them for destruction. In cancer cells, NRF2 activity runs amok, sweeping away all cellular toxins, including chemotherapy agents. Biswal says that blocking NRF2 activity could improve the effectiveness of standard chemotherapy drugs, particularly...

Scientists unlock secret of what makes plants flower

...k the progress of the protein through the plant by tagging it with a green fluorescent protein originally isolated from jellyfish, allowing it to be detected in living tissues using highly sensitive microscope systems. The team then grafted two plants together, only one of which contained the gene for th...

Tracking sperm whales and jumbo squid

...a team of marine scientists reports the successful tagging of sperm whales and jumbo squid swimming together ...mesopelagic predator and its prey using electronic tagging techniques." Size matters The jumbo (or Humboldt) squid is a large cephalopod species found ...

Brightening prospects of using fluorescent nanotubes in medical applications

... dots, which are a popular alternative fluorescent tagging technology, contain cadmium, which is highly toxic, and so may not be appropriate for “in vivo” applications. Nanotube fluorescence is extremely stable and can last for months. Fluorescent proteins – widely used for imaging living systems – begin...

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