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Tag: "suggest" at biology news

Association of herpesvirus with lung disorder questioned

...up of Kaposi's sarcoma tissue samples. These data suggest that human herpesvirus 8 infection is not associated with Japanese cases of primary pulmonary hypertension, the investigators concluded. In contrast, the 2003 study identified evidence of HHV-8 in ten of 16 samples from U.S. patients with primary pul...

A new mechanism of regulating RNA degradation

...n1-mediated degradation (SMD). Preliminary results suggest that SMD activity affects numerous transcripts and, therefore, is a novel mechanism of gene regulation. "We don't yet understand how SMD is regulated but it must be," said Maquat. "Both Upf1 and Staufen1 can be phosphorylated, so their activities co...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

...n1-mediated degradation (SMD). Preliminary results suggest that SMD activity affects numerous transcripts and, therefore, is a novel mechanism of gene regulation. "We don't yet understand how SMD is regulated but it must be," said Maquat. "Both Upf1 and Staufen1 can be phosphorylated, so their activities co...

UCSB scientists probe sea floor venting to gain understanding of early life on Earth

...t-spreading ridge. "To explain these features, we suggest that abyssal hill hydrothermal venting occurs in frequent bursts, possibly triggered by earthquakes," said Haymon. "Such widespread and oft-repeated pulses of hydrothermal venting may stimulate microbial blooms on abyssal hill fault scarps, thus prov...

Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer

...n-tumordevelopment. The researchers' findings also suggest that this enzymesystem may be useful in developing preventative therapies against skincancer. Ultraviolet light is a knownsource of damage to our DNA, but under normal conditions humans andother mammals are capable of removing UV-induced DNA damage ...

Growth in the sea comes down to a struggle for iron

...awaii after spending 42 days at sea. Early results suggest that the struggle for iron may indeed follow something like what happens in the soil. Wells and his colleagues are evaluating the data they collected and conducting additional laboratory experiments. UMaine scientists are planning to return to the P...

Mouse brain cells rapidly recover after Alzheimer's plaques are cleared

... cells once. Accordingto Holtzman, the new results suggest that plaques might not just causedamage but also somehow actively maintain it.The study, will appear in the Feb. 5 issue of the Journal of ClinicalInvestigation.Lead author Robert Brendza, Ph.D., research instructor, began theexperiment with one key ...

Key molecule in plant photo-protection identified

... cells once. Accordingto Holtzman, the new results suggest that plaques might not just causedamage but also somehow actively maintain it.The study, will appear in the Feb. 5 issue of the Journal of ClinicalInvestigation.Lead author Robert Brendza, Ph.D., research instructor, began theexperiment with one key ...

Anti-bacterial additive widespread in U.S. waterways

...centrations for 85 U.S. streams. The study results suggest that theantimicrobial contaminant is present in 60 percent of the U.S. waterresources investigated, thereby making it the fifth most frequentcontaminant among 96 pharmaceuticals, personal care products andorganic wastewater contaminants evaluated.To ...

Research advances quest for HIV-1 vaccine

... adopted by these amino acids. These study results suggest that 4E10 interacts with gp41 at a conserved region very close to the surface of the virus and they reveal some special characteristics of 4E10 that make it unusually effective at targeting this region. Drs. Burton and Wilson are members of a scient...

Scientists detect probable genetic cause of some Parkinson's disease cases

Two new studies strongly suggest that amutation in a recently discovered gene is the most common genetic causeof Parkinson's disease identified to date. The discovery by aninternational research team provides fresh evidence that genetics maycontribute to the development of some case...

HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs

...bitors do block these key channels. "Our findings suggest that as a class, protease inhibitors may predispose individuals to QT interval problems or torsade de pointes," Dr. Badley says. Dr. Ackerman adds, "Long QT-adverse events are serious side effects in drugs, but with extra caution from physicians, thi...

Female sex hormones play a vital role in defense against sexually transmitted diseases

...f the mice results hold true for women, they could suggest vaccination protocols under combination hormone therapy to get the best benefit from the vaccine. Work in this area is important because one in every four sexually active adults is seropositive for HSV-2 and women are much more susceptible than men....

Mouse brain tumors mimic those in human genetic disorder

...associated with NF1.Results from this latest study suggest that the two are not necessarilycorrelated. Gutmann's team found that optic pathway gliomas lit up justas brightly in 2-month-old mice as in 8-month-old mice, despite thefact that the tumors were actively growing only in the younger mice."If this fin...

Enzyme allows B cells to resist death, leading to leukemia

...y of these B cells to resist apoptosis. Theauthors suggest that Lyn is involved in the development of B-CLL andthat this enzyme therefore represents an attractive target for therapy.The study will appear online on January 13 in advance of publication inthe February 1 print edition of the Journal of Clinical ...

Gene variations explain drug dose required to control seizures

...dose of drugs necessary to control their seizures, suggest basic findings by researchers at the Duke Universi...her dosages of anti-epileptic drugs. The findings suggest that, by incorporating genetic tests into the prescription process, physicians might improve outcome...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...buildup in heart and skeletal muscle. The findings suggest that such an approach should be considered as a potential gene therapy strategy for Pompe disease patients, the researchers report in a forthcoming issue of Molecular Therapy (now available online). "Gene therapy in muscular dystrophies presents a u...

U-M scientists find genes that control growth of common skin cancer

...sembling fully-formed hair follicles.These results suggest that BCCs contain cells capable of multi-lineagedifferentiation, similar to normal hair follicle stem cells from whichthey may arise.If the results of this study are applicable to human BCC, the discoveryof residual tumor cells and tumor recurrence m...

First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers

...ells, the researchers report. Cell culture studies suggest they can reproduce that success in a wide range of other cancers, too. "What's unique about these analogues is that they do all this without affecting primary tumor cells, or their blood supply," Dr. Huang said. "To our knowledge, that's a real firs...

Elephants imitate truck noises, other animals

... large number of other elephants. The new findings suggest that elephants, like parrots, bats, and dolphins, may use vocal learning to develop new communication signals for maintaining complex individual-specific social relationships, study co-author Peter Tyack of WHOI said. Tyack has studied the social beh...

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