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Tag: "solid" at biology news

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

...ty acids, or trans fats, are artificially produced solid fats used in shortening and margarine, baked goods, and the oils used to cook french fries and other fast food. Studies have shown that trans fats not only raise LDL levels in the bloodstream but lower high-density lipoproteins (HDL, or "good" choles...

Columbia research lifts major hurdle to gene therapy for cancer

...s is constructed toexploit a characteristic of all solid cancers."What's exciting is we may now be able to design a therapy that willseek out and destroy only cancer cells," said the study's seniorauthor, Paul B. Fisher, Ph.D., professor of clinical pathology andMichael and Stella Chernow Urological Cancer...

Whole genome fine map of rice completed

... fine maps of the rice genome sequences will lay a solid foundation for studying the differences among strains of rice and shed insight into mechanisms of hybrid advantages at a new level, according to BIG researchers. The efficiency and data quality of the fine maps of two strains of rice, Indica and Jap...

Open microfluidic and nanofluidic systems

...ssible surface channels which can be fabricated on solid substrates using available photolithographic methods. The simplest channel geometry which can be produced in this way corresponds to channels with a rectangular cross section. The width and depth of these channels can be varied between a hundred nano...

Researchers add new tool to tumor-treatment arsenal

...," says Dr. Thomas. "Since about 50 percent of all solid tumors contain p53, such a drug combination could dramatically improve the treatment of solid tumors." ...

New protein discovered by Hebrew University researchers

...l-destroying drugsspecifically to certain types of solid cancer tumors. The protein'stiny structure enables this carrier to penetrate specifically intotumors without harming healthy tissue and thus enhance theeffectiveness of chemotherapy. This selective penetration is based onthe fact that the blood vesse...

The death of a very special chimpanzee

...l-destroying drugsspecifically to certain types of solid cancer tumors. The protein'stiny structure enables this carrier to penetrate specifically intotumors without harming healthy tissue and thus enhance theeffectiveness of chemotherapy. This selective penetration is based onthe fact that the blood vesse...

Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells

...at potentially can be applied to cancer cells from solid tumors as well as hematological malignancies like leukemia." Naviaux looks forward to examining a wider population of cancer cells to validate the method, combining the resources of his Center with Sandia's laser expertise. A project proposal has b...

Scientists identify new model Of NK cell development

... is just the first step. We feel this is the first solid evidence supporting a new model of NK cell development, but we also know that more work needs to be done to fill in some gaps." Still, the findings appear to offer important new information about NK killer cells that may ultimately be helpful in des...

Breakthrough method in nanoparticle synthesis paves the way for new pharmaceutical and biomedical applications

...hemical technique. This renders the catalysts in a solid form, enabling them to be easily recovered and reused through simple filtering or centrifuging processes. This allows for the more efficient synthesis of a wide variety of pharmaceuticals. This improvement in the drug manufacturing process can poten...

Wiley announces publication of Databasing the Brain

...tegrated. "Databasing the Brain" Offers: * A solid foundation for the application of computer science in order to build databases, tools, and workflow environments in neuroscience * An analysis of neuronal systems in a quantitative context * Specific applications in neuroscience that reflect ...

Kinovate Life Sciences Launches Nittophase?High Performance Solid Support For Oligonucleatide Synthesis

...n Boston on May 1st. The joint development of this solid phase support product was announced on November 8t...acteristics and performance when compared to other solid supports currently on the market. NittoPhase?has great potential to decrease manufacturing costs due...

Nanoparticles offer new hope for detection and treatment

...rchers believe the technology should work for most solid tumors, because all tumors must recruit new blood vessels to obtain nutrients as they grow. Nevertheless, melanoma has unique traits that make it especially interesting as a target for nanoparticle therapy. Melanoma has a horizontal phase, when it s...

Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment

...fast enough that the transformation from liquid to solid is instantaneous. No ice crystals form and the consistency resembles a viscous glassy state. Research so far has used mouse oocytes but U-M expects to make the technology available in the clinic soon. "With traditional slow-freeze techniques, just o...

Scientists journey to southern Africa to unravel the secret world of elephant communication

...ight through it, but I think they perceive it as a solid object," says Tim Rodwell, an epidemiologist who served the dual role of camp doctor and electronics guru. Rodwell and O'Connell-Rodwell supervised construction of the campsite, which included four elevated tents, a cooking/dining area and a 20-foot...

Insight into DNA's 'weakest links' may yield clues to cancer biology

...ncer cells, said the researchers. "If you look at solid tumors in humans, you see that the chromosomes of cancer cells exhibit incredible instability," said Thomas Petes, Ph.D., chair of genetics and microbiology at Duke. "Now, we have been able to mimic some of that instability in yeast cells and can beg...

Chromosome Deletion Predicts Aggressive Neuroblastoma

...ercent of all pediatric cancers, often occurs as a solid tumor in a child's abdomen or chest. Some cases of neuroblastoma are low risk, and resolve after surgeons remove the tumor. Other cases are more aggressive, and are more likely to resist initial treatment, or to cause a relapse. Identifying the corre...

Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol

... tissues of human xenograft model. "This provides solid preclinical evidence that we can use toward development of a novel device that can measure CDK activity in human tissue within several hours," Ueno says. He adds that a clinical trial is currently under way that tests CDK activity both before and aft...

Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer

...owth of blood vessels from surrounding tissue to a solid tumor. “Recent clinical trials have shown that anti-angiogenic drugs have a favorable impact on colon and lung cancers,?said NCI Director Andrew C. von Eschenbach, M.D. “This study demonstrates that when patients with recurrent or metastatic breast ...

Gov't Creates Gene Database of Normal Human Tissues

... analyzed 100 samples of the most common pediatric solid tumor cancer, neuroblastoma (NB), which accounts for 7 percent to 10 percent of all childhood cancers. Even though the tumor samples were taken from a variety of patients with different stages of cancer, the database kicked out a list of 19 genes tha...

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