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Tag: "sclerosis" at biology news

Wisconsin scientists grow critical nerve cells

... degenerative diseases such as amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. With healthy cells grown in the lab, scientists could, in theory, replace dying motor neurons to restore function and alleviate the symptoms of disease or injury. Much sooner in the future, the advance will...

Vital step in cellular migration described by UCSD medical researchers

...erventions in autoimmune diseases such as multiple sclerosis and Crohn's disease," said the paper's first author Naoyuki Nishiya, Ph.D., a postgraduate researcher in the lab of senior author Mark Ginsberg, M.D., UCSD professor of medicine. "Since cell migration plays an important role in the immune response, a...

UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders

...stroke, spinal cord injury, brain tumors, multiple sclerosis and genetic diseases. Future studies will include investigation of stem cell biology and development, as well as therapeutic based research using adult and embryonic stem cells. The Institute for Stem Cell Biology and Medicine is a collaboration of...

Gene Signatures Predict Interferon Response For Multiple Sclerosis Patients

Multiple sclerosis (MS) can be an unpredictable disease. It develops when the body's immune system attacks healthy nerve cells and disrupts normal nerve signaling. Patients experience a wide range of symptoms—including tingling, paralysis, pain, fatigue, and blurred vi...

Harmful chemicals may reprogram gene response to estrogen

...ats with a defect in a gene called Tsc-2 (tuberous sclerosis complex 2) that made them more susceptible to uterine leiomyomas, benign tumors that are common in women over 30 years of age. These rats were then treated with DES during days 3, 4 and 5 of life, during a critical period of uterine development. Onc...

Silence the gene, save the cell: RNA interference as promising therapy for ALS

... that causes inherited cases of amytrophic lateral sclerosis (ALS), substantially delaying both the onset and the progression rate of the fatal motor neuron disease. Their results will be published in the April issue of Nature Medicine, and in the journal's advanced online publication March 13. In addition to...

Some Brain Cells 'Change Channels' To Fine-tune The Message

... with Lou Gehrig's disease, or amyotrophic lateral sclerosis (ALS), some muscle-controlling nerve cells die because too much of the brain chemical glutamate binds to the cells' AMPA receptors, and so too much calcium gets inside. If these threatened nerve cells can swap their calcium-allowing channels for the ...

Canada approves marijuana-based pain spray

...relief of neuropathic pain in adults with multiple sclerosis (MS). Canada becomes the first country in the worl...Canadian pharmacies by late Spring 2005. Multiple sclerosis (MS) in Canada MS is a disease of the central nervous system and is the most common neurological dis...

A little stress gives beneficial oomph! to immune system

...d autoimmune disorders such as arthritis, multiple sclerosis or psoriasis. In autoimmune diseases, the immune system attacks the body. "Understanding mechanisms that mobilize leukocytes to potential battle stations during stress could help us figure out ways to boost the immune response when it could be most ...

Newly Discovered 'Branding' Process Helps Immune System Cells Pick Their Fights

...h disorders include rheumatoid arthritis, multiple sclerosis and type 1 diabetes. "We show in this study that during some infections, these same types of modifications can be made to our own proteins, potentially leading to T cell attacks on the self," says Unanue. Unanue and colleagues, who publish their re...

Some Brain Cells Change Channels

... with Lou Gehrig's disease, or amyotrophic lateral sclerosis (ALS), some muscle-controlling nerve cells die because too much of the brain chemical glutamate binds to the cells' AMPA receptors, and so too much calcium gets inside. If these threatened nerve cells can swap their calcium-allowing channels for the ...

New insight into autoimmune disease: Bacterial infections promote recognition of self-glycolipids

...ibute to some autoimmune diseases such as multiple sclerosis (MS) and Guillain-Barre syndrome (GBS). There is evidence that the development of certain autoimmune diseases may be associated with a bacterial or viral infection that stimulates production of antibodies and immune cells called T cells, which are t...

VCU study shows hormone-like molecule kills cells that cause inflammation in allergic disease

... and inflammatory responses in arthritis, multiple sclerosis and heart disease. In the Journal of Immunology, published online Aug. 23, researchers demonstrated the means by which a cytokine called interferon gamma (IFNγ induces death of developing mast cells in a mouse model system. Although IFNγ i...

Climate model links higher temperatures to prehistoric extinction

... and inflammatory responses in arthritis, multiple sclerosis and heart disease. In the Journal of Immunology, published online Aug. 23, researchers demonstrated the means by which a cytokine called interferon gamma (IFNγ induces death of developing mast cells in a mouse model system. Although IFNγ i...

Endocannabinoids ?the brain's cannabis ?demonstrate novel modes of action to stress

...n such disease situations in the brain as multiple sclerosis and epilepsy, or feeding disorders. In these, their effects are similar to marijuana, except for the possible dangers of accidentally using the natural products at higher dosages." Scottish team seeks social behavior answers Nancy Sabatier of the U...

Discovery of T-cell 'traffic control' boosts new drug promise

...mental drug treats the autoimmune disease multiple sclerosis by blocking excess S1P action. The research also s...nical trial results of a new drug against multiple sclerosis (MS) recently reported by other researchers. That study showed that the experimental drug, FTY720, s...

OHSU researchers discover potential mechanism to repair brain damage linked to Multiple Sclerosis

...vent the repair of brain damage caused by multiple sclerosis (MS), complications of premature birth, and other ...similar to those seen in individuals with multiple sclerosis (MS). Further investigation revealed that the tremors were associated with the loss of myelin sheat...

Molecular Partners Required For Appropriate Neuronal Gene Repression

...vent the repair of brain damage caused by multiple sclerosis (MS), complications of premature birth, and other ...similar to those seen in individuals with multiple sclerosis (MS). Further investigation revealed that the tremors were associated with the loss of myelin sheat...

Cyberkinetics, Case to develop system to help restore extremity function

...Gate System in those with ALS (amyotrophic lateral sclerosis or Lou Gehrig's disease) and other motor neuron diseases. The study is being conducted at Massachusetts General Hospital (MGH). About FES (Functional Electrical Stimulation) FES is a method of applying low level electrical currents to the body to...

Greasing interferon's gears may pave way to greater therapeutic benefits, fewer side effects

...ients with such disorders as hepatitis C, multiple sclerosis and many types of systemic cancer, who currently benefit from interferon treatment, but sometimes find it difficult to tolerate the side effects of the high doses required. "We reasoned that if we could enhance the way interferon produces its benef...

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