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Tag: "reduction" at biology news

Alzheimer's disease to quadruple worldwide by 2050

...heimer’s disease would result in a smaller overall reduction of 9.2 million cases by 2050, because slower disease progression would mean more people surviving with early-stage disease symptoms. However, nearly all of that decline would be attributable to decreases in those needing costly late-stage disease tre...

Clot-dissolving agent may be beneficial in treatment of severe frostbite

...ramatic improvements in perfusion [blood flow] and reduction in rates of amputations when tPA was administered within 24 hours of frostbite injury, we anticipate the continued use of tPA in patients who are admitted to our institution with acute frostbite,” the authors write. “Candidates for this therapy are p...

Putting feelings into words produces therapeutic effects in the brain

...hen you attach the name ‘Harry,’ you don’t see the reduction in the amygdala response. “When you put feelings into words, you’re activating this prefrontal region and seeing a reduced response in the amygdala,” he said. “In the same way you hit the brake when you’re driving when you see a yellow light, when...

Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage

...the therapy also brought about a nearly 35 percent reduction in permanent structural to joints caused by round and after round of osteoarthritic inflammation. To date, treatment of arthritis is dominated by drug treatments like non-steroidal, anti-inflammatory drugs, COX-2 inhibitors and acetominophen. Morp...

Hawaiian treasure, macadamia nuts good for the heart

...ith the standard American diet. "We observed a reduction in LDL similar to that seen with other tree nuts like walnuts and almonds," says Griel. Individual calorie levels were used for each participant so that they did not gain or lose weight during the study. Both diets were matched for total fat, cont...

Pistachios lower cholesterol, provide antioxidants

... from the 3-ounce pistachio diet correlated with a reduction in oxidized LDL which may indicate that the lutein in pistachio nuts improves the risk of cardiovascular disease by reducing serum oxidized LDL. "Our study has shown that pistachios, eaten with a heart healthy diet, may decrease a person's CVD ris...

Statin treatment improves spatial memory in mouse models of Alzheimer's

... that statin’s effects on memory might be due to a reduction in cholesterol biosynthesis. In this study, Dr. Morcos found that nNOS (neuronal nitric oxide synthase) levels were significantly higher in the hippocampus and cortex of statin treated groups as compared to similar mice that did not receive stat...

Machine preservation may promote more organ sharing

...ceiving machine-preserved kidneys had a 50 percent reduction in the rates of viral infections and delayed graft function, which is the inability of the kidneys to start working on their own without dialysis. "The routine use of machine preservation for ECD kidneys may lower hospital costs by reducing compli...

Scripps research team sheds light on long-sought cold sensation gene

... the acute pain felt by control mice as shown by a reduction in the response to formalin injection when compared to the amount of time control mice spent flicking and licking their paws when placed on a room temperature plate. In contrast, TRPM8-deficient mice did not receive any acute pain relief from the col...

Maggots rid patients of MRSA

...no adverse reactions were reported and there was a reduction in sloughy necrotic tissue and an increase in healthy, growing tissue on removal of the last larval application. In their second study, he and his team will compare larval treatment with antibacterial silver dressings and the biogun treatment, whi...

Gene mutation linked to cognition is found only in humans

...t, type I-specific splicing site and a significant reduction in type I neuropsin expression in human and chimpanzee when compared with the rhesus macaque, an Old World monkey. This pattern suggests that before the emergence of the type II splice form in human, the weakening of the type I splicing site already ...

High-dose anticlotting drug cuts heart attack, death risk in half

... (600 mg or more) was associated with a 50 percent reduction in the risk of cardiac death or nonfatal heart attack, both during the initial hospitalization and within 30 days of the PCI procedure, a finding that was highly statistically significant (p=0.009). There was no statistically significant increase in ...

Parasites' impact goes beyond host to affect ecosystem

...ls, and infected snails -- they similarly saw less reduction of ephemeral algae by infected snails. But when researchers isolated ephemeral, or edible, algae, "we saw dramatic change," says Byers. Edible algae account for a small proportion of macroalgae on rocky shorelines ?just about seven percent ?but th...

The quest for an effective HIV vaccine presents new possibilities, challenges

...so-called killer T-cells--are responsible for this reduction in HIV levels; however, their ability to continue ...of virus produced during early infection, caused a reduction in virus levels following the acute stage of infection, or produced some combination of these effect...

Revealing the machinery underlying the 'plastic' juvenile brain

...al downregulation could regulate the developmental reduction of plasticity occurring in the adult visual cortex," concluded Pizzorusso and colleagues. They also concluded that the closure of the critical period was associated with a decrease in the ability of visual experience to drive the histone modification...

Researchers find link between food odors and lifespan in fruit flies

...s ranged from 6 percent to 18 percent ?not as much reduction as actual consumption of more food caused, but sig...s ranged from 6 percent to 18 percent ?not as much reduction as actual consumption of more food caused, but significant enough to show that food odors have a mod...

In obesity, brain becomes 'unaware' of fat

... in the animals?diets was reduced—even without any reduction in calories—the mice continuously lost weight until they reached a size comparable to control animals. Their brains?appetite control centers also regained sensitivity to leptin. “That was a surprise, a nice surprise,?Cowley said. “We had thought i...

Scripps research study shows humans and plants share common regulatory pathway

...1. "Inhibiting HSP90 resulted in a significant reduction of Nod1 protein levels," Ulevitch said. "That clearly suggests that this protein plays a key role in stabilizing Nod1 and protecting it from degradation. In contrast, turning off SGT1 did not alter levels of Nod1." In an earlier study, Ulevitch’s...

New player in commitment to life as a fat cell

...fat cell precursors. Mice lacking XOR showed a 50% reduction in fat tissue mass compared to their normal littermates. Genetically obese mice exhibited increased XOR activity and urate in the adipose tissue. Urate is a salt derived from uric acid. "Our results identify XOR as a potential therapeutic target f...

'Marathon mice' elucidate little-known muscle type

...rs were surprised to find that the fibers showed a reduction in I, IIA, and IIB MHCs and as much as a 5-fold increase in IIX MHC. Nearly 100% of muscle fibers in the transgenic animals contained abundant MHC IIX mRNA and protein, they found, as compared to only 15%?0% in normal animals. PGC-1â also changed...

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