Live vaccines more effective against horse herpes virus
...he same symptoms from the initial infection can be reactivated by stress later in life. Osterrieder will present his new findings on vaccine effectiveness, involving a limited study of 15 horses, at a luncheon meeting with other veterinarians and specialists at the annual American College of Veterinary Internal...Researchers discover mechanism for multiplying adult stem cells
...e what happens in laboratory mice when the gene is reactivated in adult tissue where it has long been dormant. Hochedlinger found that when he switched the gene on, the mice immediately formed tumors in the gut and in the skin where the gene was active. When he switched the gene off, the tumors subsided, demonst...Sleeping beauty plays a significant role in identifying cancer genes
...h and made the genes jump again. This research had reactivated the jumping genes from millions of years of evolutionary sleep; hence the name Sleeping Beauty. In the two current research studies, specially designed Sleeping Beauty transposons were introduced into mouse DNA and made to jump around in the nucleus...NYU biologists map out early stages of embryo formation
...cting in early embryogenesis are often erroneously reactivated in cancer cells. The research is the latest in a series of studies conducted at NYU's Center for Comparative Functional Genomics in collaboration with researchers at Harvard and Yale Universities, which set the stage for these most recent findings. ...Restoring silenced suppressor gene kills lung-cancer cells
...he cells' growth. The study also showed that the reactivated gene is highly effective in stopping the growth of...ggests that if this gene could be delivered to, or reactivated in, the tumor cells of lung-cancer cases that are deficient in this gene, it should have a therapeut......ipheral nervous system. When a latent infection is reactivated (by stress of many kinds), HSV-1 proteins are synthesized and new infectious virus particles are formed. These virus particles migrate along the neuronal axons to the epithelial cells of the skin. Viral growth in the skin, or other mucous membranes w......d Spring Harbor Laboratory. When the researchers reactivated p53 in the mice they found that the liver tumors c...ould be used to switch on p53 activity. "When we reactivated p53 in these mice, we saw two distinct tumor phenotypes," said Jacks. "In lymphomas the responses we...