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Tag: "progressive" at biology news

Research team identifies new Alzheimer's gene

... memory and thinking problems in older people. The progressive neurological disorder afflicts an estimated 5 million Americans, a number expected to triple by 2050. “We have entered a new era in medical research. Today’s technologies permit us to survey a sufficient number of letters throughout the human gen...

Ancient DNA traces the woolly mammoth's disappearance

... process over tens of thousands of years involving progressive loss of genetic diversity,” said Dr. Ian Barnes, of Royal Holloway, University of London. “For the mammoth, this seems much more likely to have been driven by environmental rather than human causes, even if humans might have been responsible for kill...

Gene responsible for common hearing loss identified for first time

...enetic and environmental factors. The outcome is a progressive hearing loss as the growing bone in the middle ear interrupts the sound waves passing to the inner ear. While the causative factors remain unknown, now one of the genetic components has been identified, Ms Thys told the conference. “The gene in which...

Extra-aggressive form of idiopathic pulmonary fibrosis identified

...iopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disorder from which most patients die within 5 years after diagnosis. The disease is characterized by the insidious onset of dyspnea or cough and usually evolves slowly. Now, Selman and coworkers present in an article published in the onlin...

Gene expression patterns predict rapid decline in idiopathic pulmonary fibrosis patients

...ng disease typically characterized by the slow but progressive onset of shortness of breath or cough. Most patients live about five years after diagnosis. However, according to a new study being published today in the online journal PLoS ONE, a subset of patients with a specific genetic profile has a much more r...

Human stem cell treatment restores motor function in paralyzed rats

...lls directly into the spinal cord we can achieve a progressive recovery of motor function,” said Marsala. “This ...on was evaluated in seven-day intervals, showing a progressive recovery of ambulatory functions in the rats that received stem cells. Three of the nine rats inj...

First clinical trial of gene therapy for childhood blindness

...nherited retinal degeneration. This disease causes progressive deterioration in vision, due to an abnormality in a particular gene called RPE65. This defect prevents normal function of the retina, the light-sensitive layer of cells at the back of the eye. This results in severely impaired vision from a very youn...

Study examines genetic risk factors for Alzheimer's disease

...The disease causes a distressing, irreversible and progressive loss of brain function and memory. The School of Medicine’s Department of Psychological Medicine has established a bank of more than 3,000 volunteers in South Wales, and elsewhere in the UK, to identify possible genetic risk factors for Alzheime...

Technology reveals 'lock and key' proteins behind diseases

...tic fibrosis, a hereditary disease that results in progressive disability and early death. Another important ABC protein is the Multidrug Resistance Protein (MRP), which normally removes drug metabolites and toxins from cells in our bodies but when overzealous can contribute to the drug resistance of tumours, th...

Researchers discover gene crucial for nerve cell insulation

...sorders, Charcot-Marie-Tooth disease, which causes progressive muscle weakening. The myelin sheath that surrounds a nerve cell is analogous to the insulating material that coats an electrical cord or wire, keeping nerve impulses from dissipating, allowing them to travel farther and faster along the length of ...

UW launches study testing adult stem cells for heart damage repair

...which can cause unstable angina, heart attacks and progressive heart failure when adequate blood flow is not rest...rsibly damaged, leading to significant disability, progressive heart failure and often death. ...

DNA ends: Common tool, different job

...erode a little bit further. Some have likened this progressive shortening to a genetic biological clock that winds down over time. In fact, when telomeres reach a "critical length," the cell can no longer multiply ?a characteristic sign of cellular senescence. In certain cells, such as our germ cells or bake...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

... stable disease or 55 percent of the patients with progressive disease. According to Dr. Laurent-Puig, this might be due to the cascade of molecular interactions that occur after epidermal growth factor meets its receptor, EGFR. The KRAS enzyme is a key component to these molecular actions, but mutations in ...

Cancer researchers add spice to research against rare neuromuscular disease

...r the inherited disorder, which resembles a slowly progressive form of Lou Gehrig's disease and affects only men. The compound, a distant chemical relative of a component of the spice curry, dramatically slowed the progression of the disease in mice that carried the mutant human gene that causes the disease. Th...

NIH announces phase III clinical trial of creatine for Parkinson's disease

...e brain in which patients develop symptoms such as progressive tremor, slowness of movements, and stiffness of mu..., there are no proven treatments that can slow the progressive deterioration in function. Creatine is marketed as a nutritional supplement. Studies have sugges...

Pregnancy hormone key to repairing nerve cell damage

... attacks the myelin surrounding nerves, leading to progressive loss of sensation and movement. MS affects approximately 2.5 million people worldwide and Canadians have one of the highest rates of the disease in the world. "It is thought that during pregnancy, women's immune systems no longer destroyed the mye...

Computer with brain connections changing quality of life of paralyzed

...w research on brain-computer interaction. ALS is a progressive disease that destroys neurons affecting movement. The study appears in the latest issue of Psychophysiology. The article reviews the usefulness of currently available brain-computer –interfaces (BCI), which use brain activity to communicate through e...

German researchers develop first non-invasive test to measure skin aging

...neration causes the appearance of wrinkles and the progressive loss of skin smoothness. The technique measures relative amounts of collagen and elastin by a single factor, which can be positive or negative, like temperatures. Higher values of the factor correspond to higher collagen content, and to lower elastin...

Transplanted brain cells hold promise for Parkinson's disease

...ue functioning normally rather than displaying the progressive loss of movement control that characterizes the disease. "We are very cautious but to us, it’s an indication that stem cells have promise for Parkinson’s disease," says Dr. Cesario V. Borlongan, neuroscientist at the Medical College of Georgia and...

New technology to speed up research into Huntington's disease

...ound 8 in 100,000 people. It is characterised by a progressive decline in cognitive functioning (including memory loss, intellectual decline and disorientation) together with the appearance of abnormal movements and impaired motor skills (such as unsteady gait and poor coordination). There is currently no cu...

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