Genomic Analysis Uncovers New Targets for HIV Vaccine
...ed with HIV that appear to have helped some of the patients fight off the virus and delay the onset of full-bl...CHAVI, pooling their cohorts of carefully selected patients and using the latest in genome-wide screening technology, 18 months to discover the three genes, tha...Scratch no more: Gene for itch sensation discovered
...to scarring. Effective treatment options for itchy patients are limited. Historically, scientists regarded itch as just a less intense version of the pain sensation. As a result, research on itching has been somewhat neglected. "Many genes have been identified in the pain pathway," says Chen, associate profe...Identified main genetic variants involved in response to HIV
...a large scale study on genetic differences between patients infected by HIV, and is the first study of this ki...d genetic data was compared to blood virus load in patients during the first two years after the infection, and also to the rhythm of immune degradation as a re...Enzyme delivered in smaller package protects cells from radiation damage
...high dose whole-body irradiation often is given to patients with blood and lymphatic cancers to wipe out their...ducting a phase I/II clinical trial in lung cancer patients consisting of twice-weekly swallowed MnSOD for protection of the esophagus from chemoradiotherapy da...Innovative smallpox vaccine research study to be conducted at Case Medical Center
...be used in immune-compromised individuals, such as patients with HIV or individuals with certain skin conditions such as eczema,” says Robert A. Salata, M.D., chief of the Division of Infectious Diseases at Case Western Reserve University School of Medicine and UHCMC. The new vaccine, IMVAMUNE®, is differ...Brain inflammation may be friend, not foe, for Alzheimer's patients
...ise that its presence in the brains of Alzheimer’s patients would be assumed to be part of the problem. In the original development of his mouse, Shaftel worked closely with Stephanos Kyrkanides, D.D.S., Ph.D., associate professor in the Eastman Department of Dentistry and an expert on using a class of vir...Blood test may help signal tumor's remission, return in throat cancer patients
...e University of Michigan, found that throat cancer patients who showed a decline in several cancer-related pro...and swallowing, in many cases physicians and their patients are now opting for a combination of chemotherapy and radiation as a first line of treatment. However...Liver cancer patients with high serum levels of hepatitis B virus face poorer outcomes
...g the prognostic value of serum HBV DNA levels for patients with liver cancer undergoing chemotherapy. They found that patients with high pre-chemotherapy levels of HBV DNA had a significantly increased incidence of severe hepat...Math that powers spam filters used to understand how brain learns to move our muscles
...movements, whether babies trying to walk or stroke patients re-connecting brain-body muscle links. In their report this week in Nature Neuroscience, the team says their new tool could make it possible to predict the best ways to teach new movements and help design physical therapy regimens for the disable...The insect vector always bites twice
...improve strategies of prevention and care of young patients in the context of seasonal transmission of the disease. The objective of the work conducted on human African trypanosomiasis was to analyse the antibody response to identify exactly, in total saliva extract of Glossinia flies, the immunogenic prot...Research team identifies new Alzheimer's gene
...nd prevention therapies, and the identification of patients and at-risk people most likely to benefit from tho... active in vulnerable brain cells from Alzheimer’s patients and that the GAB2 protein produced by this gene is present in those brain cells containing tangles. ...New bacterium discovered -- related to cause of trench fever
...the microbes that causes severe infections in AIDS patients in the U.S was the same species that caused trench...r’s research group found that all pet cats of AIDS patients infected by B. henselae also had the infection in their blood. In fact, about 41 percent of all the...Studies to find better ways to preserve human eggs, ovarian tissue under way
...del for other tissues and organs. “What we tell patients is that right now the standard of care for people who are going through cancer therapy is to use egg donors later on,” says Dr. Adelina M. Emmi, reproductive endocrinologist and medical director of MCG Reproductive Laboratories of Augusta. Treatme...Longer treatment benefits sleep apnea patients
... they routinely used CPAP each night. In addition, patients were evaluated for daytime symptoms such as excess...s of CPAP therapy. The findings suggest that most patients should use CPAP for at least 7.5 hours each night to realize the greatest possible benefits of thera...Brain holds clues to bipolar disorder
... these markers can help clinicians determine which patients will respond best to certain treatments. Neuroimaging also can help predict which patients of those who are genetically predisposed to bipolar disorder will develop symptoms of the disease....Newly found sensing system enables certain bacteria to resist human immune defenses
...treat infectious agents that can be transmitted to patients in hospitals via contaminated medical implants. Findings by Dr. Otto’s research group are published in the May 29 issue of the Proceedings of the National Academy of Science. Other well-known types of gram-positive bacteria include agents that cause ...Research shows cord blood comparable to matched bone marrow
...ical cord blood transplants may offer blood cancer patients better outcomes than bone marrow transplants, acco...estigators compared outcomes of pediatric leukemia patients who received unrelated bone marrow transplants with those who received umbilical cord transplants. W...Sun exposure early in life linked to specific skin cancer gene mutation
...different mutation, on the NRAS gene, was found in patients who had sun exposure later in life (between ages 5...melanomas. Researchers interviewed 214 melanoma patients in North Carolina about their risk factors for melanoma and about the various places they had lived....Dual-imaging technique useful before -- and during -- brain surgery
...ating room can improve the functional abilities of patients who undergo brain surgery. Neuroradiologist Jame...images produced from functional MRI data also help patients understand what is happening in their head and how the surgery will be conducted. “We can essenti......al Research in Manhasset, NY and more than a 1,000 patients with rheumatoid arthritis. The genes will help tel...s the largest collection from rheumatoid arthritis patients in the world. Following the cellular pathway, it has been shown that PTPN22 influences the “tri...