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Tag: "nih" at biology news

Not-for-profit publishers call NIH public access rule a missed opportunity

.. The final National Institutes of Health (NIH) rule on Enhanced Public Access to NIH Research Information is wasteful of federal research dollars and a missed opportunity to take advantage of available technology and existing efforts, according to a group of the nation's leading not-for-profit medical and scientific publishers. The final rule ignores significant free access policies alread...

NIH Calls on Scientists to Speed Public Release of Research Publications

The National Institutes of Health (NIH) announced today a new policy designed to accelerate the public's access to published articles resulting from NIH-funded research. The policy ?the first of its kind for NIH ?calls on scientists to release to the public manuscripts from research supported by NIH as soon as possible, and within 12 months of final publication. .. These peer-reviewed, NIH-funded...

NIH Researchers Discover How Insulin Allows Entry of Glucose Into Cells

Researchers from the National Institutes of Health have discovered the critical sequence of events by which insulin stimulates the entry of glucose into fat cells. .. . “This finding provides useful information for understanding disorders in which cells have difficulty using insulin, such as insulin resistance and type 2 diabetes,?said NICHD Director Duane Al...

NIH renews network focused on how genes influence drug responses

Findings will pave the way for individually tailored therapiesContinuing its strong support for studies on how genes affect responses to medications, the National Institutes of Health anticipates spending more than $150 million over five years to renew its Pharmacogenetics Research Network (PGRN). The research of this nationwide network of scientists will eventually help doctors tailor drug presc...

NIH creates nationwide network of molecular libraries screening centers

The National Institutes of Health (NIH) today announced it is awarding $88.9 million in grants to nine institutions over three years to establish a collaborative research network that will use high-tech screening methods to identify small molecules that can be used as research tools. Small molecules have great potential to help scientists in their efforts to learn more about key biological proces...

California computer scientists double volume of data in NIH biotech repository

Faster computation of haplotypes provides insight into genetic basis of human diseaseHigh-throughput sequencing of an individual's DNA yields a map of genetic variation which can give clues to the genetic underpinning of human disease. The current technologies collect genotypes, or information from the individual's two chromosomes. Yet many scientists believe that drilling down to the variation...

NIH launches comprehensive effort to explore cancer genomics

The National Cancer Institute (NCI) and the National Human Genome Research Institute (NHGRI), both part of the National Institutes of Health (NIH), today launched a comprehensive effort to accelerate our understanding of the molecular basis of cancer through the application of genome analysis technologies, especially large-scale genome sequencing. The overall effort, called The Cancer Genome Atla...

The reason why antiviral therapy can't annihilate HIV infection, and what to do about it

Antiviral therapy has been used to suppress HIV replication and has dramatically improved the clinical course of disease in affected patients. But the existence of viral reservoirs precludes the complete elimination of HIV from treated patients. In a new study appearing on November 1 in The Journal of Clinical Investigation, Tae-Wook Chun and colleagues from the NIH offer new insight into the er...

Two NIH initiatives launch intensive efforts to find roots of common diseases

The Department of Health and Human Services (HHS) today announced the creation of two new, closely related initiatives to speed up research on the causes of common diseases such as asthma, arthritis and Alzheimer's disease. . One initiative boosts funding at the National Institutes of Health (NIH) for a multi-institute effort to identify the genetic and environmental underpinnings of common illn...

New data from NIH lab confirms protocol to reverse type 1 diabetes in mice

New data published in the Nov. 24 issue of Science provide further support for a protocol to reverse type 1 diabetes in mice and new evidence that adult precursor cells from the spleen can contribute to the regeneration of beta cells. . In 2001 and 2003, researchers at Massachusetts General Hospital (MGH) demonstrated the efficacy of a protocol to reverse of type 1 diabetes in diabetic mice. Thr...

NIH neuroscience microarray consortium launches high-throughput genotyping services

The NIH Neuroscience Microarray Consortium today announced that it has added high-density genotyping on both the Affymetrix and Illumina platforms to its list of services. Stan Nelson, the principal investigator at UCLA, says that "adding ultra-high throughput genotyping for its user-base of ~10,000 investigators across the world keeps the Consortium current with the demands of the scientific com...

NIH announces phase III clinical trial of creatine for Parkinson's disease

The NIH National Institute of Neurological Disorders and Stroke (NINDS) today is launching a large-scale clinical trial to learn if the nutritional supplement creatine can slow the progression of Parkinson's disease (PD). While creatine is not an approved therapy for PD or any other condition, it is widely thought to improve exercise performance. The potential benefit of creatine for PD was ide...

NIH researchers discover protein that appears to regulate bone mass loss, the cause of osteoporosis

An estimated ten million Americans suffer from osteoporosis, and another 34 million Americans are at risk of developing the disease, which is characterized by a severe loss of bone mineral density, fragile bones and an increased risk of hip, spine and wrist fractures. The basic mechanism behind osteoporosis involves an imbalance between bone mineral formation and loss, but the detailed biological...