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Tag: "missing" at biology news

Scratch no more: Gene for itch sensation discovered

... brain. So they began to study some mice that were missing the GRPR gene to find out how they were different from normal mice. "The research was a little disappointing at first," Chen says. "The knockout mice seemed to have the same reactions to painful stimuli as normal mice." But when post-doctoral fello...

One species, many genomes

...ad in just a few days, is already available. Still missing are the computational algorithms to interpret the anticipated flood of data....

Common cancer gene sends death order to tiny killer

...ged the DNA of two sets of colon cancer cells, one missing p53 and the other containing healthy p53. They the...ancreatic cancer cells known to contain damaged or missing p53, they found that those cells had limited or zero miR-34a. "With no p53 gene or miR-34a to st...

'Lucky 13' as new gene discovery offers further hope for childhood blindness

...being the case, restoration of even a tenth of the missing protein may be enough to restore vision. So our findings, together with the recently announced clinical trials, hold great promise." Mutations in LCA5 are relatively rare. As it is a recessive gene, a child would need to be carrying two copies of ...

U-M researchers discover gene switched off in cancer can be turned on

... a gene called Brahma, or BRM, is silent – but not missing – in some cancer cells. By exposing the BRM protein to an inhibitor drug, the researchers were able to turn the gene back on, allowing BRM to be expressed. The researchers found this gene is turned off in about 15 percent of tumors studied, including...

The mouflons of the Kerguelen archipelago

...ving on the Islands between 1988 and 1996. For the missing years, the researchers appealed to the hunters who wintered there. “We got the missing DNA samples from hunting trophies and managed to go all the way back to the son of the founders,” sa...

Scientists close in on missing carbon sink

...eek. The study, which sheds light on the so-called missing carbon sink, concludes that intact tropical forest...fy possible strategies for mitigating it." The missing carbon For years, one of the biggest mysteries in climate science has been the question of what ...

Philandering female felines forgo fidelity

...tudy area had been sampled. At least some of these missing fathers undoubtedly resided outside the study area. The findings corroborate established studies on ranging patterns of female and male cheetahs. Female cheetahs occupy a home range averaging some 833 square kilometers in size, whereas a male’s te...

An 'elegant' idea proves its worth 25 years later

...in small amounts in large doses to make up for the missing urea cycle enzyme they inherited," says Ada Hamosh, M.D., M.P.H, clinical director of the McKusick-Nathans Institute of Genetic Medicine. "Sodium phenylacetate and sodium benzoate already know how to eliminate nitrogen in urine, so having more in the...

Researchers publish first marsupial genome sequence

...lements that are present in placental mammals, but missing from marsupials —that is, the genetic factors that may underlie many of the differences between the two types of mammals. Interestingly, about one-fifth of the key functional elements in the human genome arose during this relatively recent evolut...

Executable biology -- Computer science sheds light on animal development

...he model to test hypotheses that would fill in the missing pieces in silico before performing actual lab experiments. By running their model with a wide variety of gene mutation scenarios and comparing results with available laboratory data, they found that the fate of C. elegans vulval precursor cells de...

Deconstructing brain wiring, one neuron at a time

...ction. "The core idea is to use a virus that is missing a gene required for spreading across synapses but to provide the missing gene by some other means within the initially infected cells," says Ian Wickersham, Ph.D., postdocto...

Gene found for rare disorder may reveal new pathway in mental retardation

...ial features and none of the limb defects, such as missing hands or fingers, that are hallmarks of classical cases of CdLS. The genes play important roles in early development, and when mutated, cause brain abnormalities. "Our work suggests that a subset of patients with mental retardation may have mutati...

Brown cancer biologists identify major player in cell growth

...licated. This is a critical juncture. If genes are missing or broken, these alterations are passed on to the new cell -- and could result in disability or in diseases such as cancer. So biologists are keenly interested in identifying the accelerators that rev-up cell division. Ets transcription factors, a...

Tumor-suppressor gene is critical for placenta development

... to, the protein encoded by the E2f3 gene. Embryos missing both genes lived three days longer than the embryos missing Rb only, but all died before birth. "This showed that the interaction of these two proteins is de...

20-year study shows significant rise in childhood obesity, especially among girls

...hould point out, however, that the weight data was missing from a greater percentage of the 16 year-olds' records in 2002 and this could be because some of the more overweight teenagers refused to be weighed." Key findings included: In 2002, about a fifth of four-year-olds - 22 per cent of girls and ...

Failure to meet United Nations sanitation target could affect millions of the world's poorest

...2004, we do see that countries that are at risk of missing either or both targets are more likely to be in the lowest income categories," she said. "They are also the fastest growing countries, with population-doubling rates of about 30 years. At the same time, some of the wealthiest developing countries hav...

Lost dogs found more often than lost cats, study suggests

... waited about a day to do so. The cats that stayed missing during the study may have been in a shelter, and c...g what kind of methods they used to search for the missing animal. The researchers also asked the owners if the animal was wearing an identification tag; a r...

Global 'sunscreen' has likely thinned, report NASA scientists

... aerosols are doing globally gives us an important missing piece of the big picture of the forces at work on climate." The study uses the longest uninterrupted satellite record of aerosols in the lower atmosphere, a unique set of global estimates funded by NASA. Scientists at GISS created the Global Aeros...

Scientists re-grow dental enamel from cultured cells

... toward production of tissue to replace damaged or missing enamel, and ultimately, regeneration of whole teeth. ...

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