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Tag: "marrow" at biology news

Spleen may be source of versatile stem cells

...ood, the spleen is turnedon to supplement the bone marrow in replenishing your blood supply. Wemay find that the spleen kicks in to help with many more biologicalemergencies. What has been considered a practically unnecessary organmay actually provide critical healing cells," says Faustman, anassociate prof...

Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs

...al trial using stem cells generatedwithin the bone marrow to grow new blood vessels that could improvecircul...ulating factors (growth factors), to prod the bone marrow torelease a type of stem cells called endothelial progenitor cells, whichare used by the body to for...

Placenta Is A Rich Source Of Blood Stem Cells

...he laboratory, so they must be harvested from bone marrow by needle aspiration, a painful procedure, or coaxed into the blood and then collected. Both methods yield only a limited number of blood stem cells. For more than a decade, scientists have believed that blood stem cells are made only in the embryo ...

Potential Cure for Lymphoma in HIV patients

...fused back into the patient to repopulate the bone marrow wiped outby the chemotherapy.Before the transplant, patients were given one of two conditioningregimens, either high dose chemotherapy alone or in combination withradiation therapy, to destroy the cancerous cells. Most (17 patientsversus three) recei...

Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation

...blood could help physicians predict whether a bone marrow stem cell transplant will successfully restore a population of infection-fighting cells called T lymphocytes in a child. This research, by investigators at St. Jude Children's Research Hospital, is published in the journal Blood. This finding could ...

Discovery Could Lead To Novel Approaches In HIV Treatment

...could be alsoapplicable to patients requiring bone marrow transplantation to curetheir cancer....

Scientists identify new model Of NK cell development

...from a common source ?progenitor cells in the bone marrow ?they take different paths in developing into full...d much more frequently in lymph nodes than in bone marrow or circulating blood. In other words, they had a hunch traditional thinking about the origin of hum...

The very unexpected life and death of a leukemic cell

...is an incurable disease in which cells in the bone marrow grow and survive to the point where they become abnormal and malignant (leukemic). The progression of the disease is slow and there has been a lack of information regarding the rate of production of CLL cells, and the time-course of their death. For...

White blood cell waste disposal system plays critical regulatory role

...lls that are constantly being produced in the bone marrow and released into the blood stream where they migrate out of the blood and roam the body in search of potentially harmful foreign substances. Neutrophils have a short lifespan and often die via a programmed cell death pathway called apoptosis within ...

Single stem cells from bone heal a broken heart

..., human stem cell population derived from the bone marrow that has the capacity to induce generation of new ...anded novel multipotent stem cells from human bone marrow regenerate myocardium after myocardial infarction, JCI ...

Multi-purpose protein regulates new protein synthesis and immune cell development

...s from IRE1 knock-out embryos into mice whose bone marrow had been destroyed by radiation. He found that stem cells deficient in IRE1 could reconstitute all types of blood and immune cells in the transplanted mice, but their mature B lymphocytes were defective. Without IRE1, lymphocytes don't develop a B ce...

Protein That Promotes Survival Of Stem Cells Might Be Key To Poor Leukemia Prognosis

...ed anemia and had severely reduced numbers of bone marrow (BM) cells, such as HSCs and progenitor cells. This was strong evidence that Mcl-1 was needed to maintain these cell populations. The team also demonstrated that BM cells lacking Mcl-1 did not multiply when removed from mice and cultured in the labo...

Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells

...tas (afterbirth) following child birth. Adult bone marrow must be harvested from living donors through an in..., cord blood cells are less mature than adult bone marrow cells and thus do not need to perfectly match the patient's immune-related blood proteins, called an...

White Blood Cell 'Waste Disposal' System Plays Critical Regulatory Role

...lls that are constantly being produced in the bone marrow and released into the blood stream where they migrate out of the blood and roam the body in search of potentially harmful foreign substances. Neutrophils have a short lifespan and often die via a programmed cell death pathway called apoptosis within ...

Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells

...tas (afterbirth) following child birth. Adult bone marrow must be harvested from living donors through an in..., cord blood cells are less mature than adult bone marrow cells and thus do not need to perfectly match the patient's immune-related blood proteins, called an...

Breakthrough isolating embryo-quality stem cells from blood

...l research requires millions of these cells. Bone marrow donors are routinely treated with a drug known as G-CSF which "mobilises" stem cells from the bone marrow into the blood. After G-CSF treatment the donor's blood is passed through a centrifuge and back into...

Researchers pioneer new gene therapy technique using natural repair process

...ly shortened by systemic infection, and while bone marrow transplants can be used to treat the disease, they are not always successful. "SCID is ideal for this sort of therapy because you only need to correct the defect in a small number of immune cells to fix the problem," said Dr. Porteus, assistant prof...

Researchers Closer To Helping Hearing-Impaired Using Stem Cells

... the day when a profoundly deaf patient’s own bone marrow cells could be used to let him or her hear the wor...n the laboratory, stem cells taken from adult bone marrow into cells with many of the characteristics of sensory nerve cells -- neurons -- found in the ear. T...

Stem cells in bone marrow replenish mouse ovaries

...eviously unrecognized stem cells found in the bone marrow and blood of mice can "restock" a depleted ovary w...ll progenitors, putative stem cells, in mouse bone marrow and blood. In addition, the researchers also found these markers in human bone marrow and blood. Re...

Circulating stem cells play small role in lung repair

...f reparative lung stem cell originated in the bone marrow of the transplant recipient. "It's possible in th...hromosomes. Cells produced by the recipient's bone marrow have an X and a Y (male) chromosome. Lung transplant recipients are vulnerable to pulmonary injury ...

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