Brain Scans Reveal How Gene May Boost Schizophrenia Risk
...orly on such tasks. Earlier studies had shown that inheriting two copies of the more common val version leads to a slightly higher risk for schizophrenia and a signature pattern of midbrain dopamine activity.** To see how the two gene versions affect the living human brain, the NIMH researchers scanned 24 heal...Depression gene may weaken mood-regulating circuit
...ty. Previous NIMH-supported studies had shown that inheriting the short variant more than doubles risk of depression following life stresses,** boosts amygdala activity while viewing scary faces,*** and has been linked to anxious temperament. Yet, how it works at the level of brain circuitry remained a mystery....New insights into how Huntington's disease attacks the brain
...untington's disease possesses a 50 percent risk of inheriting the illness. In the United States, the disease strikes 30,000 people and places another 150,000 persons at risk. The disorder affects males and females equally and crosses all ethnic and racial boundaries. ...Defective Gene Linked to Two Inherited Immune Deficiencies
...of a person so affected has a 50 percent chance of inheriting the mutation and being predisposed to IgA deficiency and CVID. “A test for TACI defects would enable the diagnosis of more children and their relatives with these immune deficiencies,?says Dr. Geha, senior author of the study and the James Gamble Pr...Agreement will speed research on microbicides for women
...of a person so affected has a 50 percent chance of inheriting the mutation and being predisposed to IgA deficiency and CVID. “A test for TACI defects would enable the diagnosis of more children and their relatives with these immune deficiencies,?says Dr. Geha, senior author of the study and the James Gamble Pr...Biologists Crack Genetic Code for Specialized Spider Silk
...of a person so affected has a 50 percent chance of inheriting the mutation and being predisposed to IgA deficiency and CVID. “A test for TACI defects would enable the diagnosis of more children and their relatives with these immune deficiencies,?says Dr. Geha, senior author of the study and the James Gamble Pr...Study finds drug may cut down involuntary movements
...rson with Huntington's have a 50-percent chance of inheriting the disease. Thirteen years ago the gene that causes the disease was identified by scientists, and now a simple blood test can tell people whether they will develop the disease or not. But since there is no way known to prevent the disease or slow ...U of MN researchers identify ataxia gene
...ln, with the President having a 25 percent risk of inheriting the mutation. "We are excited about this discov... each of their children has a 50 percent chance of inheriting the mutation and developing ataxia sometime during their lifetime. The onset of SCA5 usually occurs ...New findings offer more complete view of breast cancer gene mutations in US population
...cause of the hereditary form of the disease. Women inheriting these mutations have a 40 to 85 percent lifetime risk of developing breast cancer, as well as an increased risk of ovarian cancer. To date, most of the studies on BRCA1 and BRCA2 mutations have focused on families known to be at high risk for brea...Gene therapy injected into the brains' of mice with Huntington's disease
...ld of an affected parent has a 50 percent risk for inheriting the disease. Genetic testing can identify mutated gene carriers destined to suffer from HD. Unlike other neurodegenerative disorders, identification of the genetic markers provides a unique opportunity to intercede therapeutically before or extremel...Test reveals effectiveness of potential Huntington's disease drugs
...rson with Huntington's have a 50 percent chance of inheriting it. More than 250,000 people in the United States have the disorder or are at risk for it. There is no cure, but several drugs are used or are being tested to relieve symptoms or slow Huntington's progression. The disease affects a part of the...Inheriting a tendency to brain infection
...--and were therefore at higher than normal risk of inheriting two copies of a faulty gene. In 2005, Casanova later identified a 15-year-old boy who developed brain damage due to herpes simplex infection. Casanova found that the boy's blood cells failed to produce an important immune signalling molecule, type...Parental genes do what's best for baby
...undermine the natural benefits organisms gain from inheriting two sets of genes. If one copy of a gene is damaged, for instance, then the second copy can compensate; imprinted genes lose this safeguard and so are more susceptible to disease. Errors in imprinting have also been linked to cancer and other gene...Largest genomic search finds genes that may contribute to autism
...ere are genes that heighten a person's chances for inheriting breast cancer or heart disease. Autism is actually a spectrum of disorders that inhibits a person's ability to communicate and develop social relationships. It is often accompanied by extreme behavior challenges. Autism Spectrum Disorders are dia...