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Tag: "failure" at biology news

Bioartificial kidney under study at MCG

...ells will help intensive care patients with kidney failure survive is under study at the Medical College of G...rlip, MCG nephrologist specializing in acute renal failure and a principal investigator on the study. "If you have renal failure in the ICU, your mortality is...

Neuronal 'traffic jam' marks early Alzheimer's disease

...ormal protein that clogs neurons, leading to their failure and eventual death. The researchers said their fi...nce that late-stage Alzheimer's disease involves a failure of the machinery that transports proteins within neurons. In studies with fruit flies, Goldstein and...

Ants Genetic Engineering Leads To Species Interdependency

...l, ahandicap that would lead to certain population failure in the field.The new findings suggest that specialization involving reliance oninterspecific hybrid workers has left these species unable to surviveindependently of one another.Sara Helms Cahan, Glennis E. Julian, Steven W. Rissing, TanjaSchwander, J...

Researchers add new tool to tumor-treatment arsenal

...nt reports of the under-dosing of patients and the failure to blunt the disease. When cancer cells are treated with a DNA-damaging agent, a cancer-suppressing gene known as the "guardian of the cell" (a protein called p53) responds by either killing the cell, if the damage is too severe, or allowing the can...

Potential Cure for Lymphoma in HIV patients

...ardiomyopathy (aweakening of the heart) and kidney failure due to treatment toxicitiesand died a few weeks after the transplant. Opportunistic infections,such as herpes zoster and cytomegalovirus infection, also occurred in afew patients after the transplant, but were managed with appropriatetherapy.Througho...

HIV Infection Still On The Rise

... socioeconomic, but the increase also represents a failure of prevention, write the authors. For instance, the search for a vaccine against HIV has so far produced only negative results, while microbicides have proved disappointing. Although the ABC message (abstinence, be faithful, use a condom) is popular...

Research Gives Hope For Liver Damage

...atients suffering from liverdamage (cirrhosis) and failure may benefit from research by theUniversities of Ed...me treatable. More womenin the UK now die of liver failure than do of cancer of the cervix."There has been a fourfold increase in the number of men aged 45-54d...

Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation

...receiving such a transplant will experience either failure or significant delay in the reconstitution of the T cell population. Moreover, if the transplant is successful, T cells arising from donated stem cells will be available to launch attacks on the patient's cancer cells--the so-called "graft-versus-tum...

New insight into people who 'see' colors in letters and numbers

...ross-activation might develop, they theorize, by a failure of the "pruning" of neural connections between the areas in the developing brain. The rare condition called synesthesia--in which people's sensory perceptual circuitry seems to be miswired--was long dismissed as an oddity not worthy of scientific st...

Implanted Devices Detect High-Risk Heart Failure Patients

...timize the cardiac function of patients with heart failure have provided new insights into which patients mig...of Cardiology in Orlando. "When you talk to heart failure patients, many times their perceptions of how they feel do not match with their actual clinical stat...

Special Imaging Study Shows Failing Hearts Are 'Energy Starved'

...gh CK. Then, 17 patients with histories of heart failure were similarly tested to measure the CK flux. Resu...ctors may contribute to human heart failure, but a failure in the energy supply would certainly affect the heart’s function if supply can’t be met.?/p>...

Norovirus, AIDS vaccine and Hepatitis Virus

...nfect the liver, and in some cases can cause liver failure requiring a transplant for survival. The protein interferon, produced by animal cells when they are invaded by viruses, is released into the bloodstream or intercellular fluid to induce healthy cells to manufacture an enzyme that counters the infecti...

Iron exporter revealed that may explain common human disorder

...ing ferroportin died early in development due to a failure of iron transfer from mother to embryo. Mice defic...e, perturbations in iron homeostasis result from a failure to control iron export through ferroportin, leading to increased iron release from macrophages and e...

Single stem cells from bone heal a broken heart

... transplantation. Myocardial infarction and heart failure are associated with major morbidity and mortality and there are currently limited therapeutic opportunities for intervention. This study provides the first demonstration of a single, human stem cell population derived from the bone marrow that has th...

UNC launches study of liver injury caused by drugs

...er injury is the most common cause of sudden liver failure nationwide and the most common reason why new drugs fail to obtain approval by the U.S. Food and Drug Administration, said Dr. Paul Watkins, DILIN Steering Committee chairman and the study's principal investigator at UNC. "This is the case even thou...

Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression

...o defeat. Excessive inflammation can lead to organ failure and death, and this is exactly what happens when people are stricken with septic shock. Likewise, the loss of control of genetic expression is the underlying cause of various forms of cancer--for instance the overexpression of genes that cause the ce...

Multiple-drug resistant gene expression pattern predicts treatment outcome for pediatric leukemia

...strategies to combat drug resistance and treatment failure for children with ALL. Nearly 80% of children wit...ng 20% often exhibit drug resistance and treatment failure that is poorly understood. In some cases, patients are resistant to multiple drugs that have very li...

Doctors closer to using gene analysis to help trauma patients

... go on to develop complications that lead to organ failure and death, which is the most common cause of death after traumatic injury ?sepsis and multisystem organ failure. So the goal is to use functional genomics as a tool to identify those patients who, after severe trauma and burn injury, will go on to ma...

FDA Warns About Antipsychotic Drugs and Elderly

...t seemed to be either heart-related (such as heart failure or sudden death) or from infections (pneumonia). The atypical antipsychotics fall into three drug classes based on their chemical structure. Because the increase in mortality was seen with atypical antipsychotic medications in all three chemical cla...

Master gene controls healing of skin in fruit flies and mammals

...at the lesions were scar tissue resulting from the failure of the body surface barrier to develop properly. Confirming her suspicions, the mutant embryos turned out to be much more permeable to a dye than normal embryos. The group also showed that the genes active in the mutant flies' lesions were activated...

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