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Tag: "evidence" at biology news

A gene's first 'kiss' sets off that affair known as puberty

...ale puberty, respectively. "We now have very good evidence that the GPR54 gene and its switch, the kisspeptin protein molecule produced by KiSS-1, are key to the initiation of puberty, when GnRH is released," Dr. Plant said. "However, it's unlikely that they act alone. Other signaling systems, some of which ...

Association of herpesvirus with lung disorder questioned

...s from a small number of subjects. They looked for evidence of HHV-8 in samples of lung tissue from 10 patient... concluded. In contrast, the 2003 study identified evidence of HHV-8 in ten of 16 samples from U.S. patients with primary pulmonary hypertension. The researche...

Yellowstone microbes fueled by hydrogen, according to U. of Colorado study

...thathydrogen is its fuel," Spear said. "We've seen evidence of water onMars, and we know that on Earth, hydrogen can be producedbiogenetically by photosynthesis and fermentation or non-biogeneticallyby water reacting with iron-bearing rock. It's possible thatnon-biogenic processes produce hydrogen on Mars and...

Controversial drug shown to act on brain protein to cut alcohol use

...hich made it popular in the 1960s drugculture, and evidence of toxicity to certain nerve cells in rodentstudies have discouraged careful studies of its clinical potentialagainst drug and alcohol addiction. The FDA has not approved use ofIbogaine in the U.S.Scientists at UCSF's Ernest Gallo Clinic and Research...

Neuronal 'traffic jam' marks early Alzheimer's disease

... Medicine. According to Goldstein, there has been evidence that late-stage Alzheimer's disease involves a fai... plaque formation, to see if we could detect early evidence of abnormal axonal transport," said Goldstein. The researchers used mice that had been engineered to...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

...al gene transfer into a protist, scientists report evidence in the DNA sequence that E. histolytica likely pic...tic lifestyle), Loftus says scientists found ample evidence of a variety of gene families characteristic of more complex organisms. For example, a family of mem...

Antarctic ice shelf retreats happened before

...ave been underestimated. This is some of the first evidence that a shift in ocean currents can actually destroy ice shelves. In this case it's possible that a preceding warm period may have primed the ice shelf to disintegrate when the ocean currents shifted.' The scientists analysed sediments from the botto...

Newly-discovered class of genes determines ?and restricts ?stem cell fate

...is known to be involved in some tumors, which adds evidence to the stem-cell origin for some cancers. This theory proposes that many cancers may arise from normally scarce resident stem cells that grow uncontrollably, rather than from the vast majority of differentiated cells that make up organs where cancers...

Scientists Replicate Hepatitis C Virus in Laboratory

...t have all the properties of the whole virus. This evidence together with an analysis of the replicated viral ...a cell culture medium. The NIDDK scientists found evidence of HCV proteins and HCV RNA within the human liver cells in the culture. Electron microscopy showed ...

Scientists detect probable genetic cause of some Parkinson's disease cases

...ry by aninternational research team provides fresh evidence that genetics maycontribute to the development of some cases of Parkinson's disease. Thefindings could lead to the development of a genetic test to detect themutation in individuals at risk. The research team includesinvestigators at the National Ins...

Newly discovered virus linked to childhood lung disorders and Kawasaki disease

...irus, nine of whom were subsequently found to have evidence ofrecent infection with another virus as well. Of ... second study, which was initiated when they found evidence ofthe virus's genetic structure in respiratory secretions from an infantwith classic signs of Kawasa...

Bound for destruction: Ubiquitination protects against improper Notch signaling

... activate theNotch receptor. Hayashi’s group found evidence that Nedd4 and Dx viewith each other to regulate Notch activity during endocytosis, and thatNedd4 actually destabilizes Dx in the presence of Notch. Thiscompetition between two ubiquitin ligases to permit or suppressactivation of a signaling pathway ...

HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs

...ng protease inhibitors, the researchers looked for evidence of other patients with similar experiences. To do this, they used the U.S. Food and Drug Administration's voluntary drug side-effect database, the Adverse Event Reporting System. They identified 24 cases of heart rhythm disturbances -- all of which w...

Study finds more than one-third of human genome regulated by RNA

...or of biology Christopher Burge, provides thefirst evidence that microRNAs influence a large percentage of life'sfunctions.The team developed a computational method to define the relationshipbetween microRNAs and their target genes. In December 2003, the samegroup identified 400 genes in the human genome targ...

NYU researchers simulate molecular biological clock

...or of biology Christopher Burge, provides thefirst evidence that microRNAs influence a large percentage of life'sfunctions.The team developed a computational method to define the relationshipbetween microRNAs and their target genes. In December 2003, the samegroup identified 400 genes in the human genome targ...

Mitochondrial DNA mutations play significant role in prostate cancer

... cancer."We believe this study provides convincing evidence that mitochondrialmutations play an important role...ostate cancer," said Dr. Petros."This is the first evidence that individuals who inherit a mutation ofthe mitochondrial DNA are at an increased risk of developi...

Female sex hormones play a vital role in defense against sexually transmitted diseases

...accinated mice. "These studies add to the growing evidence that we need to promote more gender-specific medical approaches in future," she said. "We have to increase awareness in both the medical community as well as the public regarding sexually transmitted diseases and women." Extending these findings int...

An HIV Protein Plays a Surprising Role in Gene Activation

... Michael Green work with human cell lines and find evidence that Tat can also stimulate PIC assembly. While most transcription factors bind to DNA, Tat binds to an area at the end of newly emerging viral RNA called the transactivation response element (TAR). Once bound, Tat recruits a cellular complex called...

New Clues Add 40,000 Years to Age of Human Species

...a's Lake Turkana basin, researchers have uncovered evidence suggesting human bones found at that time are roug...sin, a setting that has provided so much important evidence regarding human evolution,?says Brown. “However, while our research pushes back our time of origi...

Gene variations explain drug dose required to control seizures

...Sciences, the investigators report the first clear evidence linking variation in genes involved in the action or metabolism of the anti-epileptic drugs, carbamazepine and phenytoin, to the drugs' clinical use. The study is the first to emerge from a partnership, aimed at tailoring the treatment of epilepsy to...

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