Jump-starting T Cells In Skin Cancer
...ins. How these vaccines work and why they are only effective in some patients remains unclear. Pierre Coulie an...er vaccination may help in the development of more effective anti-tumor vaccines. Tumor-specific T cells can be detected in the blood and the tumors of many mel...Protein discovery could unlock the secret to better TB treatment
...tein that could unlock the secret to quicker, more effective treatment of TB by waking TB bacteria in the body. Once the TB bacteria are active again, the disease becomes treatable using common drugs like antibiotics. Scientists believe that uncovering the molecular structure of this protein will lead the way ...Columbia research lifts major hurdle to gene therapy for cancer
...etherapy based on the new technique should also be effective for a widerange of tumors - such as ovarian, breast, brain (glioma), skin(melanoma) and colon cancer - because the virus is constructed toexploit a characteristic of all solid cancers."What's exciting is we may now be able to design a therapy that wi...Dysentery uses 'sword and shield' to cause infection
..., the dysentery bacteria has evolved into a highly effective and dangerous infection." ...Topical treatment shown to inhibit HIV and herpes simplex virus infection
... is an urgent need for the development of safe and effective vaginal microbicides," Marla Keller, M.D., Assistant Professor of Medicine at the Mount Sinai School of Medicine and the researcher who presented the data. "While condoms offer protection against sexually transmitted infections, their effectiveness i...Controversial drug shown to act on brain protein to cut alcohol use
...e.The research also showed that Ibogaine was quite effective inpreventing relapse, or "falling off the wagon" -...e type ofbehavior in alcoholics for which very few effective drugs exist," Janaksaid.The scientists confirmed in a cell model that Ibogaine stimulated GDNFactivi...Tiny particles could solve billion-dollar problem
...t nanoparticles of gold and palladium are the most effective catalysts yet identified for remediation of one of the nation's most pervasive and troublesome groundwater pollutants, trichloroethene or TCE. The research, conducted by engineers at Rice and the Georgia Institute of Technology, will appear next mon...Research advances quest for HIV-1 vaccine
...ial characteristics of 4E10 that make it unusually effective at targeting this region. Drs. Burton and Wilson are members of a scientific consortium of laboratories, the International AIDS Vaccine Initiative's Neutralizing Antibody Consortium (IAVI), which is focused on understanding broadly neutralizing anti...A much-needed shot in the arm for HIV vaccine development
...s toward the critical goalof developing a safe and effective HIV vaccine to help curb the globalHIV/AIDS pandemic.""Being from the continent worst hit by the HIV/AIDS epidemic that hasclaimed more than twenty million lives and wiped out decades ofdevelopment gains," said Pascoal Mocumbi, "I do believe that thi...Research on Worms Yields Clues on Aging
...t well understood. Suchresearch could lead to more effective treatments for epilepsy....Learning to fight an adversary that won't stay down
...ing the bacterial pathogens to the newest and most effective drugs so as to avoid overuse and the accompanying onset of resistance. "There are a relatively small number of antibiotics that have come out that are new, and some of them are very potent and act against most resistant strains," he says. "But the c...Live Recombinant Adenovirus Vaccine Technique Explored
...recombinant HPV major capsid protein (L1) provides effective immunity to HPV infection. Dr. Ketner and his colleagues theorized that a live recombinant adenovirus could be made to express L1 as the virus replicated in the body and thereby create a lasting immune response. The researchers inserted the L1 gene i...New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
...ee weeks of treatment whether the therapy would be effective ?10 weeks before traditional methods would show a response. "This is an important issue in terms of patient quality of life. Do you want to go through seven weeks of treatment only to find two months later that it had no effect? Using MRI tumor diff...Gene variations explain drug dose required to control seizures
...nts with epilepsy and their physicians to reach an effective dose of the medications that control seizures, said David Goldstein, Ph.D., director of the IGSP Center at Duke University Medical Center and senior author of the study. "In medicine today, physicians must rely on a one-size-fits-all approach when m...Solution to Pollution: New Bacteria Eats Toxic Waste
...sed around the world, is an inexpensive and highly effective solution to pollution. “This project shows mother nature’s capability to be a master engineer,?said Ron Sims, biological and irrigation engineering department head. “Past disposal practices and accidental spills have put these carcinogens in our env...Muscle-targeted gene therapy reverses rare muscular dystrophy in mice
...ffort at Duke University Medical Center to find an effective treatment for Pompe disease. The Duke team earlier developed enzyme replacement therapy, in which a normal version of the faulty enzyme in those with the disease is infused weekly. In clinical trials of the replacement therapy, the infusions have alr......model, the analogues were between 91 to 99 percent effective in stopping the spread of breast cancer cells, the researchers report. Cell culture studies suggest they can reproduce that success in a wide range of other cancers, too. "What's unique about these analogues is that they do all this without affectin...Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine
...tists develop a vaccine that is significantly more effective atprotecting children against the disease. The St....ans we can begin to develop a vaccine that is more effective inchildren than those that are currently available,?Kriwacki said.Elaine Tuomanen, M.D., chair of In...Study: Soap And Water Work Best In Ridding Hands Of Disease Viruses
...variable and sometimes poor effects, becoming less effective after multiple washes, Sickbert-Bennett said. For ...nds, physical removal with soap and water was most effective since some viruses are hardy and relatively resistant to disinfection. A report on the findings app......tists develop a vaccine that is significantly more effective atprotecting children against the disease. The St....ans we can begin to develop a vaccine that is more effective inchildren than those that are currently available,?Kriwacki said.Elaine Tuomanen, M.D., chair of In...