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Tag: "drugs" at biology news

Chemists create 'Superbowl' molecule; May lead to better health

... molecule is capable of delivering a wide range of drugs ?from painkillers to chemotherapy cocktails ?to specific areas of the body, potentially resulting in improved treatment outcomes and perhaps saving lives, the researchers say. The molecule also shows promise for a wide range of other applications, i...

DNA Molecules Used To Assemble Nanoparticles

...ou wanted to make a therapeutic that targeted five drugs to five different cells, it would be 25 synthesis steps the traditional way," Baker said. At two to three months per synthesis, and a significant loss of yield for each step, that approach just wouldn't be practical. Instead, the Baker group will cr...

New push for public health, AIDS spending at African Union summit

...ng treated with a cocktail of antiretroviral (ARV) drugs that inhibit the progression of their disease, which has no known cure. But demand for free drugs vastly outstrips their supply, the cost of the drugs - at some $US600 annually for the rest of a pat...

UAB scientists discover the origin of a mysterious physical force

...a substantial part of the process of designing new drugs is based on understanding how substances penetrate cell membranes to enter cells. These drugs are often proteins designed to prevent or strengthen the action of other substances. In these cases,...

Protein discovery could unlock the secret to better TB treatment

... again, the disease becomes treatable using common drugs like antibiotics. Scientists believe that uncoveri...ure of this protein will lead the way to designing drugs which enable treatment of dormant and multidrug resistant TB. In England and Wales around 400 peopl...

Controversial drug shown to act on brain protein to cut alcohol use

...rug Ibogaine open the way for development of other drugs toreverse addiction without Ibogaine's side effects, potentially addingto the small arsenal of drugs that effectively combat addiction. Derivedfrom a West African shrub, Ibogaine has been championed f...

Neuronal 'traffic jam' marks early Alzheimer's disease

... provide information that might be used to develop drugs to preserve the molecular transport system and thu...ans, the transport machinery could be a target for drugs to preserve that machinery." The researchers plan to continue their exploration of the transport ma...

UW's Rosetta software to unlock secrets of many human proteins

...ientists can then use to conduct research into new drugs andtreatments.Rosetta works by virtually folding protein sequences into thousands ofpossible shapes, based on certain protein folding "rules" known byscientists. These rules are summarized in the program and are termedthe "Rosetta score." The program...

Researchers find how protein allows insects to detect and respond to pheromones

...ientists can then use to conduct research into new drugs andtreatments.Rosetta works by virtually folding protein sequences into thousands ofpossible shapes, based on certain protein folding "rules" known byscientists. These rules are summarized in the program and are termedthe "Rosetta score." The program...

Computers to be used to find blueprint for new influenza drug

...an be of great assistance in drug design. Normally drugs are produced by trial and error in a process that can take many years. Professor Williams and his colleague Dr Gus Ruggiero will use part of the grant from the Biotechnology and Biological Sciences Research Council to buy computers with a combined p...

Inexpensive, mass-produced genes core of synthetic biology advances at UH

...that canproduce energy, neutralize toxins and make drugs and artificial genesthat could eventually be used in gene therapy procedures. Gene therapyis a promising approach to the treatment of genetic disorders,debilitating neurological diseases such as Parkinson’s and endocrinedisorders such as diabetes. Th...

HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs

A widely-used class of drugs that keep the HIV-virus infection from progressing...s made the discovery about a class of prescription drugs known as "HIV protease inhibitors." Drugs in this class go by the generic names of lopinavir, nelfin...

Research on Worms Yields Clues on Aging

...ty School ofMedicine in St. Louis. When exposed to drugs used to treat epilepsy inhumans, worms lived longe...d youthful functions longer thannormal.Because the drugs affect nerve signals, the researchers' observationssuggest that the nervous system influences aging ...

Finding Cures For Tropical Diseases: Is Open Source An Answer?

...mpanies. In many occasions I'veseen very promising drugs candidates or related research get cannedbecause n...n the full post. Onlyabout 1% of newly developed drugs are for tropical diseases, such asAfrican sleeping sickness and dengue fever. While patent incentive...

Learning to fight an adversary that won't stay down

...cterial pathogens to the newest and most effective drugs so as to avoid overuse and the accompanying onset of resistance. "There are a relatively small number of antibiotics that have come out that are new, and some of them are very potent and act against most resistant strains," he says. "But the clinici...

Scientists seek answers on what activates deadly anthrax spores

...ote germination will enable discoveries leading to drugs that block the process." The research is being paid for by a $152,687 grant from the Southeast Regional Center of Excellence in Biodefense and Emerging Infections, based at Duke University, one of eight such regional centers funded by the National I...

Jefferson Virologists Coax HIV Out of Hiding

...hers came up with the powerfulcocktail of anti-HIV drugs known as highly active antiretroviraltherapy (HAAR...an previously triedagents, making it vulnerable to drugs and the body’s immune system. Ifthe new technique proves its mettle, the work could lead to improved...

Enzyme allows B cells to resist death, leading to leukemia

...sis to normal and treatment of malignantcells with drugs that induce cell death decreased both Lyn expressionlevels and activity ?suggesting a direct correlation between high Lynactivity and the ability of these B cells to resist apoptosis. Theauthors suggest that Lyn is involved in the development of B-CL...

Gene variations explain drug dose required to control seizures

...might enable doctors to better predict the dose of drugs necessary to control their seizures, suggest basic... trial and error to find the dose of anti-epilepsy drugs appropriate for them. The researchers found that variants of two genes were more likely to be found...

Purdue proves concept of using nano-materials for drug discovery

...mbranes in an effort to speed the discovery of new drugs for a variety of diseases, including cancer. The ...n order to test the potential effectiveness of new drugs to treat diseases. Membranes, which surround cells and regulate the movement of molecules into and o...

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