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Tag: "disease" at biology news

Wisconsin scientists grow critical nerve cells

... to restore function and alleviate the symptoms of disease or injury. Much sooner in the future, the advance will allow researchers to create motor neuron modeling systems to screen new drugs, says study leader Su-Chun Zhang, an assistant professor of anatomy and neurology in the Stem Cell Research Program ...

Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer

... groups, confirm that in situations where residual disease remains, adjuvant chemotherapy alone in high-risk breast cancer patients is suboptimal and that the addition of locoregional radiation therapy is important to achieve the highest cure rate," the authors write. In an editorial, Timothy Whelan, B.M., ...

Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down

... groups, confirm that in situations where residual disease remains, adjuvant chemotherapy alone in high-risk breast cancer patients is suboptimal and that the addition of locoregional radiation therapy is important to achieve the highest cure rate," the authors write. In an editorial, Timothy Whelan, B.M., ...

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

...nd triglycerides and increases one's risk of heart disease and certain cancers. In the Jan. 28 issue of Cell...mechanism, decreasing cholesterol levels and heart disease risk, explained Spiegelman, who is also a professor of cell biology at Harvard Medical School. Satu...

Genes In The Interferon System Important In Systemic Lupus Erythematosus

Two genes with very strong associations withthe disease systemic lupus erythematosus (SLE) have been ident...l be possible todiscover the mechanisms behind the disease SLE, and maybe otherautoimmune diseases at the molecular level," says Professor LarsRönnblom. "Itis...

Source of molecular triggers in cutaneous T cell lymphoma identified

...nt may be useful to induce tolerance in autoimmune disease and transplantation," ...

Protein discovery could unlock the secret to better TB treatment

...e body. Once the TB bacteria are active again, the disease becomes treatable using common drugs like antibiotics. Scientists believe that uncovering the molecular structure of this protein will lead the way to designing drugs which enable treatment of dormant and multidrug resistant TB. In England and Wales...

Novel technology detects human DNA mutations

...e most critical step in correlating the SNP with a disease or drug sensitivity.To do so, Nanosphere scientists employ a two-step process calledClearReadTM technology. This method sandwiches a target DNA SNP segment between two oligonucleotide sequences to greatly increase detection specificity and sensitivit...

New, automated tool successfully classifies and relates proteins in unprecedented way

...ls. This technical feat opens a new way toidentify disease proteins and drug targets by helping to show which...phy. Getting thisinformation is critical to foil a disease like cancer, where you mightwant to identify and disable part of a tumor cell's machinery needed top...

Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs

...eir legs --a condition called peripheral vascular disease (PVD). Individuals with PVD have decreased blood flow to the muscles ofthe legs, especially during exercise, which causes pain, aching,cramping or fatigue in the muscles of their legs when they walk. Thiscondition also is called " intermittent claudi...

Neuronal 'traffic jam' marks early Alzheimer's disease

Early Alzheimer's disease may be precipitated by a "traffic jam" within neur...itute researchers. In mouse models of Alzheimer's disease and in human brain samples from people with the disease, researchers observed a characteristic break...

Drug That 'Tags' Decision-making Areas Of The Brain May Aid

....According to Mukherjee, patients with Alzheimer’s disease have beenknown to have a 30 percent to 50 percent loss of these receptors “Ifthere is a gradual loss of these receptors over time, Nifrolidine couldbe a potential marker for early diagnosis of Alzheimer’s disease,?Mukherjee said.Scientists have known...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

...a histolytica, a leading cause of severe diarrheal disease in developing countries, includes an unexpectedly ...use of morbidity and mortality from a protist. The disease caused by E. histolytica is called amebiasis. The sequencing of E. histolytica was a collaborative ...

Timing is everything: First step in protein building revealed

...s'Institute for Basic Biomedical Sciences. "We see disease largely as anincorrect timing event -- the wrong thing happening at the wrong time,or the lack of the right thing."As a result, Lorsch studies the timing of how the ribosome complexitself assembles and how other factors come and go as it translatesge...

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...added. A decade ago, CLL was considered a uniform disease of immature white blood cells that didn't die, wit...ve also since discovered that CLL is not a uniform disease but rather a disease that follows two distinct clinical courses in patients. Some patients require n...

Scientists Replicate Hepatitis C Virus in Laboratory

...nds, which may lead to new therapies for the liver disease that results from infection with HCV. Scientists a...AS). “Until recently, research on this infectious disease has suffered from the lack of a robust in vitro model system,?says T. Jake Liang, M.D., Chief of the...

Scientists detect probable genetic cause of some Parkinson's disease cases

...ene is the most common genetic causeof Parkinson's disease identified to date. The discovery by aninternation...d be responsible for up to 5 percentof Parkinson's disease in people with a family history of the disorderand may account for 1½ to 2 percent of cases in indiv...

Computers to be used to find blueprint for new influenza drug

...e taken by people coming down with flu to stop the disease developing. The drug would work by being chemically very similar to part of the protective coating around the cells in our throats that the flu virus first attacks when a person becomes infected. The flu virus would be deceived into attacking the dr...

Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates

...g neurons in thebrain as a treatment for Parkinson disease reached the stage of humantrials over 15 years ago...vestigation. Studiesof animal models of Parkinson disease as well as clinicalinvestigations, have shown that transplantation of fetal DA neurons canrelieve th...

Ecological destruction fuels emerging diseases

...t reacting out of ignorance whenever an unfamiliar disease catches us off guard and we call that management," says Dr. Brooks. "We're always behind the curve, because we don't know where these things are coming from." In fact, while parasites like malaria are well known, we may have identified only a fracti...

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