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Tag: "discovered" at biology news

Jump-starting T Cells In Skin Cancer

...the tumor. In an unexpected finding, however, they discovered that that these cells mostly recognize tumor proteins that were not contained in the vaccine. Understanding the characteristics of the T cell populations that are expanded after vaccination may help in the development of more effective anti-tumor vac...

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

...r and a researcher at Dana-Farber, have previously discovered the PGC-1 co-activator family and several of its biochemical activities. The Dana-Farber researchers made the discovery in searching for the function of PGC-1beta co-activator that was isolated in 2002. Experiments including the measurement of gene ...

A new mechanism of regulating RNA degradation

... a similar function may occur in flies." The team discovered that Staufen1 doesn't interact with other components of the NMD complex ?and altering the amount of Staufen1 in the cell didn't change NMD function. Those observations, said Maquat, sent Kim on a hunt for what Staufen1 and Upf1 were doing. Looking a...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

... a similar function may occur in flies." The team discovered that Staufen1 doesn't interact with other components of the NMD complex ?and altering the amount of Staufen1 in the cell didn't change NMD function. Those observations, said Maquat, sent Kim on a hunt for what Staufen1 and Upf1 were doing. Looking a...

Spleen may be source of versatile stem cells

..., Massachusetts General Hospital (MGH) researchers discovered that the spleen might be a source of adult stem cells that could regenerate the insulin-producing islets of thepancreas. In a follow-up to that unexpected finding, members of thesame team now report that these potential adult stem cells produce aprot...

UCSB scientists probe sea floor venting to gain understanding of early life on Earth

...achel M. Haymon, UCSB professor of geology. Newly discovered geological and biological manifestations of hydrot...m these common features. The team describes newly discovered geological and biological manifestations of hydrothermal activity at two sites on young abyssal hill...

UAB scientists discover the origin of a mysterious physical force

...e studied this mysterious force in detail and have discovered where its origins lie. In the same way that a fla...asions, to reverse it. This abnormal behaviour was discovered by the same researchers and published in Physical Review Letters in April 2004. The scientists have...

Researchers discover way to make cells in the eye sensitive to light

Researchers have discovered a way to makelight sensitive cells in the eye by switching on a single gene.According to research published online today in Nature, the team fromImperial College London and the University of Manchester, havediscovered that activating the melanopsin g...

Protein discovery could unlock the secret to better TB treatment

...tructural & Molecular Biology, a combined team discovered the structure of a protein known as resuscitation promoting factor (Rpf). Five versions of the Rpf protein exist in TB bacteria. The paper's unveiling of the molecular structure of Rpf could be crucial to the treatment of TB in the future. Dr John W...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

...tists from the United States, Sweden and Japan has discovered that having a double dose of one protein is sufficient to change the normal balance of cells within the lining of the colon, thereby doubling the risk that a cancer-causing genetic mutation will trigger a tumor there. Roughly 10 percent of people hav...

Columbia research lifts major hurdle to gene therapy for cancer

...earchers at Columbia University MedicalCenter have discovered a way to overcome one of the major hurdles ingene therapy for cancer: its tendency to kill normal cells in theprocess of eradicating cancer cells.In a new study published in the Jan. 25 issue of the Proceedings of theNational Academy of Sciences (PNA...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

Scientists at Joslin Diabetes Center have discovered one reason why infants with low birth weight have a high potential of developing type 2 diabetes later in life. In studies of mice, the researchers found that poor prenatal nutrition impairs the pancreas's ability to later secrete enough insulin in r...

Fox Chase Cancer Center scientists identify immune-system mutation

...Feb. 24 issue of Nature. Kappes' laboratory first discovered the mice with this naturally occurring defect in F..." Kappes said. The helper-deficient mice his team discovered represent the second time that a naturally occurring mutant strain has been found and bred at Fox Ch...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...iological Chemistry (JBC), the Varki grouphas also discovered the exact cellular mechanism by which this occurs. Instudies with one of the federally approved human embryonic stem celllines, the investigators determined that the Neu5Gc is incorporated bythe stem cells when they are grown or derived from laborat...

Plants, animals share molecular growth mechanisms

A newly discovered plant protein complex that apparently switches on plants' growth machinery, has opened a scientific toolbox to learn about both plant and animal development, according Purdue University scientists. The protein complex triggers communication between ...

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...competent white blood cells. Scientists have since discovered that CLL cells do indeed turn over, with the accum...of the leukemia cells. Scientists have also since discovered that CLL is not a uniform disease but rather a disease that follows two distinct clinical courses in...

Researchers Uncover Key Step In Manufacture of Memory Protein

...20 issue of Neuron. Specifically, the researchers discovered that the enzyme carboxypeptidase E, (CPE) is needed to deliver the early, or inactive, form of BDNF ?proBDNF ?to a special compartment in the neuron (nerve cell.) Once in the compartment, proBDNF is chemically converted into active mBDNF. After mBDNF...

Plants respond similarly to signals from friends, enemies

...n living cells over time, the NC State researchers discovered that the model legume Lotus japonicus responded si...rom which the nematodes feed. The scientists also discovered that, like rhizobia and contrary to popular belief, the root-knot nematode signals plants from a dis...

Research advances quest for HIV-1 vaccine

...o broadly effective, a rare characteristic for HIV discovered thus far. The research is published in the February issue of Immunity. Vaccination has been a successful strategy for protecting humans from many potentially harmful viruses. However, designing a suitable vaccine for HIV-1 has been a highly challeng...

Scientists detect probable genetic cause of some Parkinson's disease cases

...dies strongly suggest that amutation in a recently discovered gene is the most common genetic causeof Parkinson'...re cases of Parkinson's disease than anyother gene discovered to date," says Andrew Singleton, Ph.D., chief ofthe Molecular Genetics Unit in the NIA's Laboratory ...

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