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Tag: "development" at biology news

A gene's first 'kiss' sets off that affair known as puberty

...uberty's tell-tale physical changes, including the development of breasts in girls and voice change in boys. As such, this research begins to answer one of the most vexing questions about human development: What causes puberty to begin? How is it that the full repertoire of reproductive hormones can exist at bir...

Chemists create 'Superbowl' molecule; May lead to better health

In a development that could one day score a touchdown for better health, chemists in Australia have created a "superbowl" molecule that shows promise for precision drug delivery, according to a recent study in the Journal of the American Chemical Society. Shaped like...

Viral DNA sequence a possible trigger for breast cancer

...virus, but what role this sequence plays in cancer development has remained unexplored. Katz and colleagues now show that this sequence is contained in the Env protein of MMTV and show that expression of Env in mouse breast cells transforms them. This study puts the spotlight on a potential new mechanism for vi...

Wisconsin scientists grow critical nerve cells

...ing of a toe to the rolling of an eyeball. The new development could one day help victims of spinal-cord injuries... in a developing embryo. With the ticking clock of development in mind, Zhang and his team deduced that there is only a thin sliver of time - roughly the third and...

New push for public health, AIDS spending at African Union summit

...hat fighting AIDS is not just a health issue but a development issue," she said. "Now they have to deliver on the existing protocols and develop a serious and practical strategy." Mozambique is the only country that has, thus far, committed to allocating 15 per cent of its gross domestic product to healthcare...

Jump-starting T Cells In Skin Cancer

...hat are expanded after vaccination may help in the development of more effective anti-tumor vaccines. Tumor-specific T cells can be detected in the blood and the tumors of many melanoma patients, and yet these cells are unable to kill the tumor. What causes the impotence of these T cells is a mystery. Equally m...

Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer

...tudies of DNA repair capacity and the need for the development of better laboratory tests for such studies. "When... understand the role of DNA repair capacity in the development of cancer and possibly to develop interventions to reduce cancer incidence and mortality," they writ...

Spleen may be source of versatile stem cells

...ls,Hox11 is a controller of key steps in embryonic development - includingthe formation of the spleen - but it wa... - or potentially evencells of the nervous system, development of which depends on thecorrect production of Hox11."We know that if you have a major loss of blood, ...

Genes In The Interferon System Important In Systemic Lupus Erythematosus

...ron effect.It is therefore possible to imagine the development of methods oftreatment for SLE based on blocking the function of the thyrosinkinaseenzyme," explains Lars Rönnblom.The other gene codes for a transcription factor, which also plays animportant role in regulating the interferon effect. Further functio...

Source of molecular triggers in cutaneous T cell lymphoma identified

...useful for cancer immunotherapy and promoting Treg development may be useful to induce tolerance in autoimmune disease and transplantation," ...

Protein discovery could unlock the secret to better TB treatment

...iscovery of Rpf in the TB bacteria could allow the development of methods to 'wake-up' all dormant bacteria in a patient allowing antibiotics to kill the bacteria and cure the disease." The team includes Prof Brian Henderson at the UCL Eastman Dental Institute, Nicholas Keep from Birkbeck, University of London,...

Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer

...es ofdamage to tumor formation is critical for the development of therapiesthat could help prevent skin cancer. Moreover, CPDs and 6-4PPs haveparticular potential to cause lasting damage to mammalian cells becausephotolyases ?a class of enzymes capable of efficiently repairing theselesions ?have apparently been ...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

...her the loss of imprinting is involved in cancer's development or just in its progression. "Most researchers, in...f imprinting of IGF2 contributes to colon cancer's development in the mice. It doesn't cause tumors directly, but it creates an environment which is ripe for cance...

Topical treatment shown to inhibit HIV and herpes simplex virus infection

... efficacy of PRO 2000, a topical microbicide under development by Indevus Pharmaceuticals, Inc. "There is an urgent need for the development of safe and effective vaginal microbicides," Marla Keller, M.D., Assistant Professor of Medicine at ...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

...ion of the mother. It also can occur with abnormal development of the placenta and its blood vessels, or high blood pressure, which damages vessels." In addition, many other factors can result in intrauterine growth restriction and low birth weight. The Joslin study, published in the March edition of Diabetes, ...

Fox Chase Cancer Center scientists identify immune-system mutation

...tor of the maturation process." Understanding the development of critical components of the immune system can contribute to medical advances in stimulating desirable immune responses and halting undesirable immune reactions, Kappes said. This understanding can further progress against various immune disorders, ...

Controversial drug shown to act on brain protein to cut alcohol use

...h findings aboutthe drug Ibogaine open the way for development of other drugs toreverse addiction without Ibogain...nowledge of a molecular mechanism thatshould allow development of a new class of drugs to treat addictionwithout Ibogaine's side effects," said Dorit Ron, PhD, UCS...

Elusive HIV shape change revealed; Key clue to how virus infects cells

...ison. He notes that some HIV inhibitors already in development seem to inhibit the shape change; the new findings...pin down how these compounds work and hasten their development into drugs. "The findings also will help us understand why it's so hard to make an HIV vaccine, and ...

Mouse brain cells rapidly recover after Alzheimer's plaques are cleared

...id clearance of brain plaques,made possible by the development of Abeta antibodies, affect theprogression of Alzh... would halt the progression of thedamage--stop the development of new swellings," says Brendza. "But whatwe saw was much more striking: in just three days, there w...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

...olytica genome sequence is expected to help in the development of new vaccines as well as diagnostic tests that c...A typing from the genome sequenced is allowing the development of "new diagnostic tests that help distinguish the most deadly substrains of the parasite." Dr. Alo...

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