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Tag: "detailed" at biology news

Man and mouse share genome structures

In the most detailed large-scale study to date of the proteins that package DNA, researchers have mapped a family of switches that turn genes on and off. Their findings may help scientists understand regulatory mechanisms underlying cancer and human development. The res...

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

... called PGC-1beta. Until now, scientists lacked a detailed explanation of how saturated and trans fats caused an increase in blood cholesterol and triglycerides, while diets high in unsaturated and polyunsaturated fats did not. Evidence pointed to the liver, which is responsible for the body's synthesis of t...

W.M. Keck Foundation funds study of friendly microbes

...essible database will be established that provides detailed molecular information about the gut ecosystem for researchers. A second aspect of the project aims to directly identify the products of bacterial metabolism in the intestine. The goal is to characterize previously unknown chemical compounds that pla...

Mouse brain cells rapidly recover after Alzheimer's plaques are cleared

...lls to producea dye that allowed Brendza to obtain detailed images of nerve cellbranches.To correlate brain cell changes with plaque development, Brendzainjected another dye, developed by scientists at the University ofPittsburgh, that temporarily sticks to amyloid. He showed that as theplaques appeared, near...

Key molecule in plant photo-protection identified

...lls to producea dye that allowed Brendza to obtain detailed images of nerve cellbranches.To correlate brain cell changes with plaque development, Brendzainjected another dye, developed by scientists at the University ofPittsburgh, that temporarily sticks to amyloid. He showed that as theplaques appeared, near...

Research advances quest for HIV-1 vaccine

...cines for HIV-1, the virus that causes AIDS. A new detailed structural analysis of the complex formed by an an... Jolla, California performed a study examining the detailed molecular structure of the complex formed when 4E10 binds to gp41 and determining how interaction of...

Male circumcision reduces risk of HIV transmission from women to men

...lleaguesfrom the United States and Kenya collected detailed sexual data from agroup of male Kenyan truckers and, using statistical models, developedinfectivity measures that estimate the per-sexual-act probability ofHIV transmission. The study is the first to calculate the probabilityof infection for men who ...

Ecological destruction fuels emerging diseases

... different diseases, something that will require a detailed understanding of their often complex multi-host life cycles. "It's very difficult to link these things up," he says. "It's very time consuming to do that, but without that information we don't know how these parasites are transmitted." And without ...

Breakthrough Microarray-based Technology for the Study of Cancer

...ity and flexibility of themicroarray platforms. As detailed in the PNAS paper, Agilent'sbreakthrough is founded on the modification of its gene-expressionprofiling microarray technology to improve its utility for DNA analysisapplications. This new platform provides high sensitivity, enabling CGHresearchers to...

Spider Venom Could Yield Eco-Friendly Insecticides

... King's NSF-funded research has provided the first detailed descriptions of the regions of the toxins that are essential for interaction with insect ion channels. (Ion channels allow the movement of ions -- small charged molecules -- across cell membranes.) His next challenge is to use this information to de...

Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease

...of Technology (M.I.T.). They did the largest, most detailed study to date of the protein structure that surrounds the human genome. Their findings reveal surprising and previously unknown specifics of how genes get switched on during development of the human body and in diseases such as cancer. "Each type o...

Open microfluidic and nanofluidic systems

...medicine, for example, they could provide fast and detailed analysis of blood samples in the physician's office without the need to wait several days before the sample has been returned from specialized laboratories. Other applications include customized chips for space travel in order to monitor microbes ins...

Gene Therapy For Parkinson's Disease Moves Forward In Animals

...nduced form of Parkinson's disease. The research, detailed online in the scientific publications Brain and The Journal of Neuroscience, essentially describes one strategy to halt Parkinson's disease at its onset and another strategy to treat the devastating side effects that occur when treating the disease i...

New SARS Protein Linked To Important Cell Doorway

... be attained very rapidly, and get a head start on detailed biophysical investigations of emerging diseases months before we can even begin to work with such diseases in culture." Fremont led the initial analysis, which was dedicated to identifying sequences of genetic code that might translate into proteins...

First real-time view of developing neurons reveals surprises, say Stanford researchers

...what they'll become as adults. The work, which is detailed in a paper in the March 24 issue of Neuron, took place in the brain of a small see-through fish called a zebra fish. Stephen Smith, PhD, professor of molecular and cellular physiology, and graduate student Christopher Niell immobilized a young fish a...

PANTHER Protein Classification System Database 5.0

...ely simplifies the task of capturing anddisplaying detailed pathway data,?added Dr. Thomas.“This collaboration... set of pathwaymodules has been released with such detailed molecular information. Weare pleased to see that the process notation in CellDesigner has provedto b...

Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimer's, Parkinson's Disease

...s of the deposits. Their aim is to understand the detailed assembly process for the toxic protein called amyloid plaque. Such basic understanding, they said, could lead to approaches to preventing plaque formation. The researchers led by Boris Akhremitchev are using the infinitesimal tip of a customized ato...

Gene therapy for Parkinson's disease moves forward in animals

...nduced form of Parkinson's disease. The research, detailed online in the scientific publications Brain and The Journal of Neuroscience, essentially describes one strategy to halt Parkinson's disease at its onset and another strategy to treat the devastating side effects that occur when treating the disease i...

Implanted Devices Detect High-Risk Heart Failure Patients

...from CRT-D devices is possible because they record detailed data on heart function 24 hours a day. These new findings are important for two reasons, the researchers said. First, the collected information appears to more accurately identify high risk patients who would benefit from early and aggressive therap...

Nonlinear Dynamics announces more details of its global partnership with PerkinElmer

...ife science research and analytical solutions. As detailed in a press release issued last week, PerkinElmer will distribute Nonlinear's full range of 1D, 2D and array software. However the agreement also represents the formation of an integrated partnership between the two companies, with Nonlinear now forma...

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