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Tag: "compounds" at biology news

Chemists create 'Superbowl' molecule; May lead to better health

...s have had a very limited carrying capacity. "The compounds we made are bigger versions of these original bowl...for wider applications." "I wanted a name for our compounds which acknowledged this and recognized their larger size and shape," says Sherburn. "'Superbowl' was...

UAB scientists discover the origin of a mysterious physical force

...hat create small electric fields, such as chemical compounds like those found in many detergents, this is no longer the case: the water molecules have a remarkable capacity to organise themselves into complex structures that are strongly orientated in such a way as to cancel out the electric field, and on some...

W.M. Keck Foundation funds study of friendly microbes

...oal is to characterize previously unknown chemical compounds that play important roles in regulating the properties of the microbial community and human physiology. To do so, the researchers will use a new type of mass spectrometer with an unprecedented capacity to accurately and rapidly identify these metabol...

Elusive HIV shape change revealed; Key clue to how virus infects cells

...s shape is a new route to inhibiting HIV ?by using compounds that inhibit the shape change," says Harrison. He ...ange; the new findings may help pin down how these compounds work and hasten their development into drugs. "The findings also will help us understand why it's so...

Scientists Replicate Hepatitis C Virus in Laboratory

...tion. “With this cell-based system, we can screen compounds with a cell-based assay to look for inhibitors of virus replication,?says Liang. “We can also apply this technique to develop model systems for other similar viruses.?/p> HCV is a small, enveloped, single-stranded RNA virus in the family Flavivir...

Inflammatory molecules released by pollen trigger allergies

...pollutants produce more of these allergy-provoking compounds than do pollen from unpolluted areas, possibly explaining why allergies are more prevalent in places with high levels of car exhaust emissions. Traidl-Hoffmann and colleagues showed that extracts from birch pollen and other common allergens block th...

Learning to fight an adversary that won't stay down

...expected to make the development of new antibiotic compounds easier and more productive. But in most cases the microbes continue to hold the upper hand ?and if three billion years of bacterial history is any kind of track record, we're in for an endless running battle, says Dr. Julian Davies, a microbiologist ...

Spider Venom Could Yield Eco-Friendly Insecticides

...sent an untapped reservoir of diverse insecticidal compounds that could do more than control agricultural pests. As researchers inventory more kinds of venom and uncover insecticide leads, they may be able to target insects that transmit new and emerging human diseases, such as Lyme disease and Rocky Mountain ...

Poplar trees redirect resources in response to simulated attack

...i said. "We will have to do more tests to see what compounds are formed." Ferrieri believes there may be an increase in compounds that resist microbial attack after plants have soaked up atmospheric carbon dioxide, therefore count...

Purdue proves concept of using nano-materials for drug discovery

...e used to quickly screen millions of untested drug compounds that exist in large pharmaceutical "libraries." The chips could dramatically increase the number of experiments that are possible with a small amount of protein. "It's been very hard to study these proteins because they are difficult to produce in l...

First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers

Two compounds that zero in on cancer cells spreading throughout ...s gained a lot of interest among researchers." If compounds could be found that slowed or halted cancer spread, doctors could gain valuable time in shrinking th...

ASU researchers finds novel chemistry at work to provide parrot's vibrant red colors

...coloration, but McGraw and Nogare found that these compounds are not responsible for the red colors found in the parrot species they sampled. The researchers used a chemical analysis technique called high-performance liquid chromatography to survey the pigments present in red parrot feathers. McGraw and Nogar...

Transport System Smuggles Medicines Into Brain

...coloration, but McGraw and Nogare found that these compounds are not responsible for the red colors found in the parrot species they sampled. The researchers used a chemical analysis technique called high-performance liquid chromatography to survey the pigments present in red parrot feathers. McGraw and Nogar...

Development of portable infectious disease detector

...termine the biologicalactivity of large numbers of compounds with extreme rapidity and socould have a major impact on the drug discovery process.Fifteen years ago a number of start-up companies were created to makethe goal of creating a "lab-on-a-chip" a reality. However, puttingmicroscopic arrays of channels,...

Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems

Deficiencies of growth hormone and similar compounds may reduce cancer and kidney disease late in life, but also may lead to cartilage degeneration and impaired memory and learning ability, according to research at Wake Forest University Baptist Medical Center and four other institutions. The research...

Newly Discovered Compound Blocks Known Cancer-Causing Protein

...cility, which houses a library of more than 13,000 compounds available for screening promising drugs with poten...ccomplishment led pharmaceutical companies to test compounds that block another key player in the pathway, a protein called farnesyltransferase. Blocking this pr...

Tiny scaffolding allows stem cells to become working fat cells

...ti-well assay plates and be used to test dozens of compounds at the same time," he explained. "Since these cells better resemble how cells function in living tissue, they would offer a better test than current two-dimensional cell colonies provide." Kniss is currently working with an Ohio company to consider ...

Breast-Cancer Risk Linked to Exposure to Traffic Emissions at Menarche, First Birth

... caution, because they could be explained by other compounds in vehicle exhaust or by other exposures related to the traffic emissions. "While these results are subject to the limitations of epidemiologic observational studies, they are provocative in providing evidence both of the importance of early exposur...

Effective Cancer Treatments Follow The Clock

...We have already started screening sets of chemical compounds for their ability to affect this function. We are also planning additional studies to discover the molecular signals from the circadian machinery to the immune system that might prove to be useful drug targets.?/p>...

Potential treatments for neurofibromatosis

...is year, and are experimenting with potential drug compounds now. Dr. Clapp, professor of pediatrics and of microbiology and immunology, said one target of their efforts will be mast cells, which are immune system cells that are involved in asthma and allergic reactions. Mast cells play a role in neurofibroma...

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