Bacteria collection sheds light on urinary tract infections
...ed E.coli samples collected over 40 years from the center to match up the bacteria causing UTIs with bacteri...largest repository of E.coli in North America. The center has 60,000 E.coli strains isolated from cows, birds, pigs, humans, dogs, water and the environment. ...Novel Enzyme Shows Potential As An Anti-HIV Target
... presence of SIRT1, but not when SIRT1’s catalytic center is removed. Experiments using cells taken from transgenic mice lacking SIRT1 demonstrated that introducing human SIRT1 enzymes increased Tat’s transcriptional effects in a dose-dependent manner, while treating cells with the small molecule HR73, a de...Clam embryo study shows pollutant mixture adversely affects nerve cell development
...out BrickTownship, New Jersey--a town that was the center of an ATSDR* study inthe year 2000 that documented a higher than usual rate of autismspectrum disorder and explored its link to bromoform, chloroform, andtetrachloroethylene in Brick's water supply--it got her thinking. "Myhypothesis was this: While ...Study identifies predictors of HIV drug resistance in patients beginning triple therapy
...out BrickTownship, New Jersey--a town that was the center of an ATSDR* study inthe year 2000 that documented a higher than usual rate of autismspectrum disorder and explored its link to bromoform, chloroform, andtetrachloroethylene in Brick's water supply--it got her thinking. "Myhypothesis was this: While ...Gene variations explain drug dose required to control seizures
...er for Population Genomics and Pharmacogenetics, a center of the IGSP. If the genes' predictive value is verified in clinical trials, such a "pharmacogenetic" approach might make it possible to safely reduce the time required for patients with epilepsy and their physicians to reach an effective dose of the...Purdue proves concept of using nano-materials for drug discovery
...f a Center for Membrane Protein Biotechnology. The center was created at Purdue in 2003 through a grant from...cer drugs. Engineers and scientists in the Purdue center are trying to find drugs that deactivate the pumps, which would make the chemotherapy drugs more eff...First 'atlas' of key brain genes could speed research on cancer, neurological diseases
... Center (DF/HCC), designated a comprehensivecancer center by the National Cancer Institute....Placenta Is A Rich Source Of Blood Stem Cells
...s Hospital Boston today is a 325-bed comprehensive center for pediatric and adolescent health care grounded in the values of excellence in patient care and sensitivity to the complex needs and diversity of children and families. Children's also is the primary pediatric teaching affiliate of Harvard Medical ...Plants defy Mendel's inheritance laws, may prompt textbook changes
...lowers that fully opened and radiated out from the center of a cluster. "If you take this mutant Arabidopsis, which has two copies of the altered gene, let it seed and then plant the seeds, 90 percent of the offspring will look like the parent, but 10 percent will look like the normal grandparents," Pruitt...Asthma gene clusters identified
... University of Cincinnati College of Medicine. The center specializes is combining computational resources with medicine and genetics in order to customize care for patients based on the patient's individual genetic makeup. "Dr. Hershey's research is a good example of research that we believe will benefit ...Artifical cornea lets woman blind 20 years see
...ent's eye. First, the surgeon cuts a hole from the center of the donated cornea so that the "keratoprosthesis" can be inserted into it. The next step depends on the artificial cornea model being used, but typically includes connecting a front plate to a back plate with the donor cornea tissue sandwiched in...UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders
...e stem cell studies, said Judith C. Gasson, cancer center director, stem cell institute co-director, and a professor of medicine and biological chemistry. "I see cancer and stem cells as tightly linked," Gasson said. "More and more evidence suggests that cancer is a stem cell disease. Many of our current t...Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells
...h cancers and rare genetic diseases than any other center in the world ?147 children in all. The oldest Duke patient transplanted for a lysosomal storage disease is now seven years old and has developed and progressed normally, according to Kurtzberg. Kurtzberg said their treatment successes provide a stro...Defenseless plants arm themselves with metals
...arch and Development, a multidisciplinary research center dedicated to developing a "molecular toolbox" to p...n up polluted sites. Technologies developed at the center will be commercialized through a partnership with the Midwest Hazardous Substance Research Center, a...Scientists discover that three overlapping signals in embryo help get the backbone right
...hinks of embryologically as the dominant signaling center actually is a source of a cocktail of inhibitors," he said, "so inhibition is just as specific a signal in the embryo as is an activating signal." Since they discovered noggin, Harland and his colleagues have shown that in later stages of developmen...Marine sponge yields nanoscale secrets
...olecules (that duplicate those found at the active center of the bio-catalyst of the marine sponge) onto the...lained that his research group discovered that the center of the sponge's fine glass needles contains a filament of protein that controls the synthesis of the...One gene links newborn neurons with those that die in diseases such as Alzheimer's
... the researchers looked at cells in the high vocal center region of the brains of 19 zebra finches, a kind o...e brain a few millimeters away from the high vocal center to form part of the brain pathway that controls muscle movements related to singing. The neurons tha...Supercomputers to focus brains on AIDS dilemma
... their cyclic moieties to the "east" of the active center as well as to the "west." Based on these simulations, the researchers were also able to predict that the strongest binding inhibitors should be possible with moieties on both sides, what the scientists have called "butterfly" compounds with "wings" e...Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells
...h cancers and rare genetic diseases than any other center in the world ?147 children in all. The oldest Duke patient transplanted for a lysosomal storage disease is now seven years old and has developed and progressed normally, according to Kurtzberg. Kurtzberg said their treatment successes provide a stro......rent from others Blackburn has worked on since the center accepted its first animal sample in 2000. "It's really a learning experience for us; it's a step beyond the biology, one in which we have to consider social implications," he explains. To develop the collection, animal physiologist Phil Purdy, also ...