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Tag: "causing" at biology news

Man and mouse share genome structures

...be as important as changes in the genome itself in causing diseases such as cancer. This regulatory structure, called chromatin, is a key regulator of gene expression in healthy and diseased cells, Bernstein said. Chromatin is composed of DNA spooled around bundles of histone proteins, and resembles a chain...

Protein discovery could unlock the secret to better TB treatment

...istant TB (MDR-TB). Eight per cent of the bacteria causing TB in patients are resistant to one or more drugs and one per cent show multidrug resistance. Left untreated, a person with infectious TB of the lungs infects around 10 to 15 people every year. In a study published on 1st March 2005 in Nature Struct...

Dysentery uses 'sword and shield' to cause infection

... The researchers found that shigella, the bacteria causing dysentery uses a Type III secretion system to inject proteins into human cells. This causes the cells to become inflamed, resulting in symptoms of dysentery, such as bloody diarrhoea. At the same time, the LPS chains on the surface of the bacteria ar...

Antarctic ice shelf retreats happened before

...elatively warm current, Circumpolar Deep Water, is causing high melt rates on the underside of an ice shelf i...Bay*. The gradual removal of this ice shelf may be causing the glaciers inland to flow faster, which could lead to enhanced drainage of part of the West Antarc...

Plants, animals share molecular growth mechanisms

...when genes affecting actin filaments are askew and causing altered growth. The researchers previously had learned that a large protein complex, known as WAVE, activated ARP2/3, but they didn't know specifically which WAVE protein was the actual switch. Their latest research showed that a WAVE protein they'v...

Newly discovered virus linked to childhood lung disorders and Kawasaki disease

...e of her. First headline :a newly discovered virus causing respiratory infection. Let's hope itsjust a coinci...humans,coronaviruses have been known primarily for causing colds or, morerecently, severe acute respiratory syndrome (SARS). Genetic evidencenow suggests that ...

New Technique for Tracking Gene Regulators

... using thismethod include the gene responsible for causing Huntington’s disease inmice, which is important for making advances in understandingHuntington’s disease in humans, and genes that may play an importantrole in certain cancers.“This technique can be applied to any protein that binds to specificsequen...

Bacteria collection sheds light on urinary tract infections

...ntibiotics. The researchers found that the E.coli causing the UTIs matched genetically with a sample of E.co... 40 years from the center to match up the bacteria causing UTIs with bacteria found in animals. They tested E.coli samples from dogs, cows, sheep, water and tu...

Sea skate experiment sheds light on human cell transport

..., diluting blood and other body fluids and rapidly causing death. So how do skates do it? Goldstein and Musch learned how cellular channels, or gates, spring into action when skate red blood cells become engorged with water. Vesicles, or tiny fluid-filled sacs, carry these gates up to the cell membrane. The...

Scientists collaborate to assess health of global environment

...rica, environmental change is the principal factor causing poverty, according to the assessment. Implications The assessment represents more than a catalog of environmental problems, Mooney noted. By evaluating the trade-offs that accompany decisions about ecosystem services, it will identify priorities on...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

... muscles throughout the body, including the heart, causing muscles to degenerate. Using genetically altered mice in which the gene for the enzyme had been rendered nonfunctional, the researchers demonstrated they could introduce the functioning gene and correct glycogen buildup in heart and skeletal muscle....

Purdue proves concept of using nano-materials for drug discovery

...ce a disproportionately large number of the pumps, causing the cells to become progressively more resistant t...gh the membrane's pores, it mixed with the enzyme, causing a reaction and turning blue in the process, which demonstrated that the device works. The Center fo...

Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease

...he proteins that regulate HOX genes are capable of causing or suppressing tumors. Technological breakthrough Bernstein has been studying chromosome wrappings for five years as a postdoctoral researcher in the lab of Stuart Schreiber. Together they worked out techniques to examine the way genes are packaged...

First 'atlas' of key brain genes could speed research on cancer, neurological diseases

...es are altered, thegenes they control can go awry, causing abnormalities in thedevelopment or function of nerves and related structures.Although the gene regulators were pinpointed using mouse brains, themap applies to the human brain as well. “This is the first systematic mapping of all of the major brain ...

Scientists develop new color-coded test for protein folding

...sis revealed that additional hydrochloric acid was causing the cytochrome c molecules to unfold. As a result, gold nanoparticles coated with cytochrome c began clumping together--a process that caused the solution to quickly change from red to blue as the acidity increased. The researchers were surprised to...

Researchers discover molecule that causes secondary stroke

... Several spinal fluid components were suspected of causing the vasospasm, Dr. Clark explains. They included hemoglobin, bilirubin and peroxidized lipids, and a group of bilirubin oxidation products that the researchers called BOXes. Building on Dr. Clark's earlier studies in rats, the team measured each of ...

Highly adaptable genome in gut bacterium key to intestinal health

...ic, species may be an important mechanism to avoid causing a potentially damaging or disruptive host immune response. "B. theta is an incredibly sophisticated and versatile diner," says Justin Sonnenburg, Ph.D., W.M. Keck Foundation postdoctoral research scholar in the Center for Genome Sciences. "Instead o...

Gene Therapy For Parkinson's Disease Moves Forward In Animals

... a different way to deliver the GDNF to the brain, causing the body to produce it naturally. It also produces more manageable levels of the protein in the brain. “Our strategy is a neuroprotective concept and would only be amenable for early stage patients to keep a good quality of life. It would be a huge ...

New studies suggest airborne SARS transmission is possible

Two new studies present evidence that the virus causing severe acute respiratory syndrome (SARS) may spread through the air, not just through direct contact with contaminated water droplets as previous research had shown. SARS coronavirus was detected in the air in a patient's room during the 2003 outbre...

The very unexpected life and death of a leukemic cell

... cells were both immortal and born at a slow rate, causing the slow rise in cell count over time. But researchers had been unable to find any problems with the programmed cell death machinery in CLL cells. This was a hint that perhaps the leukemia cells were not immortal, a hypothesis tested by Nicholas Chio...

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