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Tag: "vivo" at medical news

Scientist Observes real Time Generation of Neurones in Mammals

... model to study development of neural dendrites in vivo by using special microscopic imaging techniques, combined with virus gene technology. The dendrites are the string-like extensions of the neurone that spread out to reach other neurones, and serve as the points of communication between them. Th...

Astronauts can Now Feed on 'radiation-eating' Fungi

...the Einstein researchers performed a variety of in vivo tests using three genetically diverse fungi and four measures of cell growth. The studies consistently showed that ionizing radiation significantly enhances the growth of fungi that contain melanin. Both species grew significantly faster (as measu...

Nanomedicine Gives the Way for Nerve Cell Regeneration

...y. Using optic nerve and spinal cord tissues as in vivo models and dissociated retinal ganglion neurons as...y of using magnetic nanoparticles for enhancing in vivo axon regeneration, this work may have significant implications for the treatment of spinal cord inju...

Nanocomposite Labeled Cancer Cells Targeted and Destroyed by Using Lasers

...unctionality and payload than traditional small in vivo devices where the agent is conjugated directly to the surface. A laser can be used to kill cells indiscriminately, but it is really a blunt instrument. High powered lasers do so much damage that the tissue becomes opaque to further light. Yet, lowe...

DNA-damage Test Could Aid Drug Development

...esses, in vitro human models could be closer to in vivo human than in vivo mouse,' notes Shuga. 'That premise will be tested in coming years as new systems become available.'...

Antibody-based Therapies Effective at Controlling Malaria

...r P. falciparum antigens in mice and humans. An in vivo mouse model has significant advantage over the use of new world primates, the only other model for human malaria, which are labor-intensive and difficult to reproduce. These novel human reagents cured mice of an otherwise lethal malaria infection, ...

Insulin Therapy Shown to Treat Early Experimental Diabetic Retinopathy

...acodynamic properties were studied in vitro and in vivo using R28 cells in culture and SD rats respectively. Lead researcher Ravi S.J. Singh, MD, of the Pennsylvania State College of Medicine in Hershey, Penn., reports that low dose periocular delivery of insulin to the retina of diabetic rats does not ...

Study Reveals Little-known Cell Networks Vital to Circadian Rhythm

...aptive feature in most circumstances. SCN cells in vivo must synchronize not only to light-dark cycles but also to one another to coordinate circadian behavior. Lack of coupling may allow peripheral oscillators to anticipate and respond rapidly not only to the synchronizing cues emanating from the SCN but...

Antidepressents may Lower Bone Density in Older People

...theory is supported by findings of in vitro and in vivo laboratory investigations. Some data suggest that SSRIs may interfere with the function of osteoclasts and osteoblasts, cells responsible for the regular breaking down and rebuilding of bone in the body. Our findings suggest that, in this cohort, u...

Adherence of Nanoparticles to RBC- Very Effective Drug Delivery Method

...e of red blood cells dramatically increases the in vivo lifetime of the nanoparticles. Polymeric nanoparticles are excellent carriers for delivering drugs. They protect drugs from degradation until they reach their target and provide sustained release of drugs. Polymeric nanoparticles, however, suffer ...

Common Antidepressants Linked to Increased Bone Loss in Older Adults

...theory is supported by findings of in vitro and in vivo laboratory investigations," they write. "Our findings suggest that, in this cohort, use of SSRIs is associated with increased rates of hip bone loss. Further investigation of SSRI use and rates of change in bone mineral density in other populations...

Researchers Have Found the Role of Protein in Accelerating Breast Cancer Progression

...he major finding of our study demonstrates both in vivo and in vitro that inappropriate expression of PTN not only promotes breast cancer progression but that by itself PTN secretion from human breast cancer cells may be sufficient to shift that progression to a more aggressive form of breast cancer," he ...

New Understanding on Growth of Human Stem Cells

...ells (hdFs) in vitro despite removal from their in vivo microenvironment. These hdFs then provide a continuous source of supportive proteins, including insulin-like growth factor 2 (IGF-II), which they now show could be the protein to sustain hESCs. Researchers are interested in the relationship betwee...

EpiCept Accelerates Development of Phase I Clinical Study for Cancer

...nti-tumor activity in pre-clinical in vitro and in vivo studies. The molecule has been shown to induce tumor cell apoptosis and selectively inhibit growth of proliferating cell lines, including multi-drug resistant cell lines. Murine models of human tumor xenografts demonstrated EPC2407 inhibits growth of...

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