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Tag: "variant" at medical news

Prions Prevent Alzheimers Disease

...niversity of Leeds. Alzheimers and diseases like variant Creutzfeldt-Jakob Disease follow similar patterns of disease progression and in some forms of prion disease share genetic features. These parallels prompted Professor Hoopers team to look for a link between the different conditions. They found an app...

New Diagnostic Test for Mad Cow Disease Developed

...o wrongly tell people that they are suffering from variant Creutzfeldt-Jakob disease (vCJD). They insist that the new technique developed by them can detect people having fatal levels of abnormal proteins called prions, which kill off brain cells and are thought to cause the disease. Dubbed as 'Protein ...

Significant Advances in VCJD Prion Detection

...e used to confirm whether someone is infected with variant CJD . The technique, which has so far been used ... is no cure. A total of 161 people have died from variant CJD since the disease emerged in early 1990, including three people who received blood transfusions ...

Insights into Acute Promyelocytic Leukemia

... new avenues to develop treatments for some of its variant forms. Results from two new studies provide key mechanistic insights into the complex molecular events that cause a deadly type of leukemia.APL is a cancer of the bone marrow that occurs when certain developing white blood cells get stuck at a high...

Gallstone Gene Discovered by Research Team

A three fold risk increase by gene variant A group of research scientist from the Universit...ong with Romanian colleagues has discovered a gene variant which augments the possibility of developing gallstone considerably (Hepatology No. 46, 11 July 2007...

Smokers may Develop Chronic Obstructive Pulmonary Disease

...y School of Medicine and colleagues. The genetic variant we studied seemed harmless on its own, said Alirez...erefore, in combination with smoking, this genetic variant represents a risk factor for COPD. Emphysema and chronic bronchitis are components of COPD, which ...

Genetic Variation in Some Smokers Increases Chances of Developing COPD

...eloping COPD if they smoke tobacco. "The genetic variant we studied seemed harmless on its own. But when so...erefore, in combination with smoking, this genetic variant represents a risk factor for COPD," said Alireza Sadeghnejad, M.D., Ph.D., lead author. The resea...

Gene Variants for Crohn's Disease Identified

Researchers have found a gene variant that raises a childs risk of Crohns disease, which...ts of a German study that identified the same gene variant associated with the adult form of the disease.Crohns disease is a chronic and painful condition attr...

Gene Linked With Restless Leg Syndrome Spotted Out

...is clearly linked to RLS," said Dr. Rye. The gene variant is common as at least 65 pct of the population car...least one copy of it, and having two copies of the variant increases one's risk of experiencing RLS. According to Dr. Rye, carrying two copies does not guaran...

Three Gene Variants Could Hold Key for HIV Vaccine: Study

...wn immune system overcome an infection. One gene variant looks specially promising, the scientists said in a study to appear in the Friday edition of the journal Science. "These results not only approximately double our understanding of the factors that influence variation amongst individuals in how they...

Boffin Identifies Gene Causing Otosclerosis

...ents has been identified. "The gene in which the variant is located points to a pathway that contributes to...ence, we were also able to show that a more active variant of this gene is protective against the disease," she added....

Genetic Tests Could Help Decide the Right Anti-depressants

...epressants. He inserted into a mouse a defective variant of the human gene for brain-derived neurotrophic f...ty. The clear implication is that people with this variant will not be able to respond to any SSRI, which requires normal neurotrophic-factor function to work....

Childhood Abuse Increases the Risk of Alcoholism

...holism later in life if they possess a particular variant of a gene involved in the bodys response to stress...eated boys who possessed the low activity MAOA-LPR variant were more likely to develop behavior problems than boys with the high activity variant. Our aim wa...

Car Sickness for the Little Ones can Be Prevented

...f car sickness or motion sickness. Carsickness, a variant of motion sickness, happens when the eyes, inner ears and joints get conflicting clues about how fast and in what direction the body is moving, says Chamberlain, a clinical instructor at Lucille Packard Children's Hospital at Stanford in Palo Alto, C...

Proteins Behind Mad Cow Disease may Protect Against Alzheimer's

... In the human version of mad cow disease called variant Creutzfeldt-Jakob disease (vCJD), the infectious p...in damage and death. Given that Alzheimer's and variant CJD are similar, the researchers looked for a link between the two diseases. They found that the ...

Alteon Initiates Phase 2 Trial of ALT-2074 in Diabetes and Haptoglobin 2-2

...e peroxidase mimetic, in diabetic patients with a variant of haptoglobin that renders them at high risk for cardiovascular complications. This dose escalating study is designed to evaluate ALT-2074's ability to lower inflammatory cardiovascular biomarkers in patients with an elevated risk for cardiovascu...

Sleep Deprivation can Affect Competent Decision-making

...oncern for negative consequences when performing a variant of the Iowa Gambling Task. While well-rested participants learn to avoid high-risk decks and to choose from the advantageous decks, sleep-deprived participants tend to continue to choose from the risky decks as the game progresses. Michael W.L. Ch...

Genetic Variation is Linked to Substantial Risk in Heart Attack

... led by deCODE Genetics uncovered the first common variant found to be consistently linked to substantial ris...r early onset cases. This means that were the gene variant not present, there would potentially be 21 percent fewer heart attacks overall in the population and...

Cataloging the Structural Variations in Human Genetics

...ural variants that they have in common. If a given variant is contributing to a disease, it will occur at a higher frequency in people with the disease. Knowing about structural variation in the human genome will also allow geneticists to analyze single-base-pair changes more effectively, according to Ara...

Gene Variant Responsible for Acquiring Intellect and Memory in Humans Identified

Chinese scientists have identified a unique gene variant linked with learning and memory, which may help understand how humans acquired intellect and language skills much faster than their closest relatives, monkeys. Researcher Bing Su and his colleagues at the Kunming Institute of Zoology say that the ...

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