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Tag: "triggers" at medical news

Translating Structure into Function

...om an enzymes structure just what natural molecule triggers the enzyme into action -- fitting into the active site and enabling the enzyme to act as a catalyst. This was a search for the so-called substrate for the enzyme, a search that has never succeeded simply from knowing an enzymes configuration. The ...

War Trauma-hit UK Veteran Population Set to Increase

...tic event during conflict. The memory of the event triggers strong emotions, causing any number of reactions from depression and self-harm to anger, violence and drug addiction. Often, the symptoms will be so extreme that the veteran will be unable to live a normal life. Work prospects, family life and other...

Autophagy may Lead to Heart Disease

...ertrophy, or heart enlargement, and heart failure, triggers autophagy in cardiac cells. We also found that a specific autophagic gene, beclin 1, is a critical factor required for cardiac autophagy, said Dr. Hill, who holds the James T. Willerson, M.D., Distinguished Chair in Cardiovascular Diseases and the ...

Parkinsons Disease Mechanism Identified

...a genetic defect, but because some external insult triggers the death of dopamine-producing neurons. In both mice and human patients, the researchers have found evidence that neurons die because of a crippling of a particular protective enzyme that eliminates potentially damaging reactive oxygen species nor...

Insights into Acute Promyelocytic Leukemia

...XR, including its sumoylation, a modification that triggers transcriptional repression for RXR and many other transcription factors. "The presence of RXR in the PML/RARA complex not only greatly facilitates DNA binding but is also required for rexinoid-induced differentiation, demonstrating that RXR is not...

Study Finds Most Women Getting Wrong Dose of Fertility Drugs

...r ovaries, and levels of a hormone called FSH that triggers egg development. They used the calculator to check the dosage given to 161, and found that 75 per cent were being given a higher dose than required, while 15 percent were being given a lower dose of the infertility drugs. When 113 of the women we...

Rare Womens Lung Disease May Yield Insights Into Common Diseases

...at mutations in the tuberous sclerosis gene, which triggers TSC, a genetic disorder that causes tumors to form in many different organs, including the brain, eyes, heart, kidney, skin and lungs, plays a role in the cause of LAM. Her current work involves looking into the role female hormones play in the growt...

Research Studies on Molecular Switches of Gene

A single molecular on switch triggers gene activity that cause effects ranging from lea...ule that binds to a section of DNA near a gene and triggers that gene to make the specific protein for which it codes. CREB activates genes in response to a mol...

Modified Drug Therapy for Alzheimers Disease

... key enzyme in the progression of Alzheimer's that triggers the formation of amyloid plaques in the brain. Various stages in plaque formation produce toxic proteins that harm the brain, causing damage that eventually leads to dementia. Later that year, Ghosh built a molecule that binds to this key enzyme an...

Tinnitus Patients can Lead a Normal Life

...fied role. This fact alerts the patient and turn triggers the perception of auditory discomfort, according to Ms Heitzmann. The limbic system, responsible for emotions and learning, is then activated and the autonomous nervous system, which causes the discomfort. It is at these levels that intervention can ...

Allergic Individuals Should Keep Away from Cats, Say UK Scientists

...fic receptors on the surface of immune cells. This triggers the release of histamine in the body, causing symptoms such as itching, sneezing and runny eyes and nose. ...

Research Demonstrates Link Between Domestic Violence and Asthma

...n respiratory condition. "Classic environmental triggers for asthma have been carefully studied, but there is less information on the role of stress in asthma episodes," says lead researcher S.V. Subramanian, Assistant Professor in the Department of Society, Human Development and Health at HSPH. "The risk...

Holy Grail Of Dermatologists On The Verge Of Discovery

...llicles via wnt proteins. Wounding, they report, triggers new hair-producing follicles to form. This was a claim that was first made half a century ago after experiment on rabbits but which was written off as unconvincing. The new work shows the effect is real and a consequence of a molecular signal involvi...

New Pill to Suppress Menstrual Bleeding Indefinitely

...cal reason women need monthly bleeding and that it triggers health problems from anemia to epilepsy in many women. They note women have been tinkering with nature since the advent of birth control pills and now endure as many as 450 periods, compared with 50 or so in the days when women spent most of their fe...

Sleep Apnea may Increase Risk of Diabetes

...activates the bodys fight-or-flight response. This triggers a cascade of events, including the production of high levels of the hormone cortisol that ultimately leads to insulin resistance and glucose intolerance, pre-diabetic conditions that, if left untreated, can lead to the development of diabetes. Low ox...

Sleep Apnea Increases Risk of Heart Attack or Death by 30 Percent

...iography or bypass surgery) or died. Sleep apnea triggers the bodys fight or flight mechanism, which decreases the amount of blood pumped to the heart. Repeated episodes every night for a few years can starve the heart of enough oxygen when it is combined with the bodys decreased oxygen intake due to the fr...

Circadian Clocks Triggered Chemical Reactions may Be Behind Jet Lag

...e of light, and the captured energy from the light triggers a series of interactions that ultimately lead to conformational changes on the surface of the vivid protein, causing a cascade of events affecting the expression of genes, such as turning carotenoid production on and off. When they substituted a si...

Pre- and Post-menopausal Women Responses Equally to Most Sexual Desire Cues

...mines differences in sexual desire, as well as the triggers that cause them, in pre- and post-menopausal women . Participants in the study included both women who had expressed concerns regarding their own feelings of sexual desire and those who felt their levels of desire to be normal. An assessment tool w...

Antidepressant Use May Boost Fracture Risk, From Harvard Women's Health Watch

...working with an animal model found that depression triggers the release of noradrenaline, which interferes with bone-building cells. Moreover, they found that imipramine-a member of an older class of drugs called tricyclic antidepressants-reversed both depression and depression- induced bone loss. It may be...

Detecting Cold, Feeling Pain: Study Reveals Why Menthol Fresh

..., and in 2000 reported that, in mice, the receptor triggers the nerves to fire pain signals when they are exposed to high ambient heat or the fiery properties of peppery food. The study demonstrated that capsaicin and noxious heat elicit the sensation of burning pain through activation of the same receptor on...

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