Navigation Links

Tag: "toxicity" at medical news

A new century of Alzheimer's disease research

...ormally.” Dr. Lewis says the studies suggest that toxicity to neurons caused by tau begins before tangles develop. “If so, we may be able to repair that process so that the neuron can rebound,” she says. Their achievement was reported in 2005 in Science. “These tau findings changed our ideas about what th...

Gene Therapy Eradicates Pancreatic Cancer in Mice

...-BikDD combination. "All cancer drugs have some toxicity and so cause side effects, which affects the dose ...ISA-BikDD produces virtually no systemically acute toxicity or acute pancreatitis," the authors report. Dr. Abbruzzese says that the phase I clinical trial w...

New Cancer Therapy in Clinical Trial

...eing used in clinical trials. Potency and lack of toxicity to normal tissues make activation of TNF-a-related apoptosis-inducing ligand (TRAIL) death receptor signaling an attractive and exciting target for cancer therapy, and it is currently being tested in clinical trials. However, most cancer cells have...

Tumor Painting to Fight Against Cancer

...te. Olson and his team are preparing the necessary toxicity studies before seeking approval from the Food and Drug Administration to begin clinical trials. Chlorotoxin:Cy5.5 could be used in operating rooms in as little as 18 months. All clinical studies will have consenting adult participants.Olson and his...

Right Foods Could Improve Drug Effectiveness, Lower Drug Costs

...ts too, the authors add. For example, the major toxicity associated with lapatinib is diarrhea, probably caused by unabsorbed drug. So taking a lower dose with food should "reduce the amount of unabsorbed drug, and therefore theoretically also reduce the frequency and severity of diarrhea." But the auth...

US FDA may Be Asked to Monitor Toxic Levels of Cigarettes

...eports on tobacco, said it could help minimize the toxicity of cigarettes. New products would need FDA approval before they could be sold, according to the legislation. The bill also would authorize the FDA to set national standards for tobacco products to control how they are made, as well as force the disc...

Value Meal Would Lower Drug Costs

...he authors add, may have other benefits. The major toxicity associated with lapatinib is diarrhea, probably caused by unabsorbed drug. So taking a lower dose with food should "reduce the amount of unabsorbed drug, and therefore theoretically also reduce the frequency and severity of diarrhea." Patients shou...

Interactions Between Food and Drugs Could Lower Drug Costs

...he authors add, may have other benefits. The major toxicity associated with lapatinib is diarrhea, probably caused by unabsorbed drug. So taking a lower dose with food should "reduce the amount of unabsorbed drug, and therefore theoretically also reduce the frequency and severity of diarrhea." Patients shou...

Bayer and Onyx Submit Supplemental New Drug Application for Nexavar to Treat Liver Cancer

...may fulfill a serious unmet need with a manageable toxicity profile." HCC, the most common form of liver cancer, is responsible for about 90 percent of the primary liver cancers in adults. It is the fifth most common cancer in the world and the third leading cause of cancer-related deaths globally. Over 600...

Children Using Slide in Playground Treated for Exposure to Poisoning

...e created lead deposits could be another source of toxicity for children, it was then warned. Soil often is contaminated by airborne lead particles that drop to the ground and become "a persistent, hard to remove component of the dust matrix." Playground equipment is another possible source of lead contamin...

Inherited Genes Linked to Toxicity of Leukemia Therapy

...ted into routine clinical care, we should see less toxicity among children being treated for ALL." Relling is ...chemotherapy drugs were linked to gastrointestinal toxicity and infection, respectively. In the consolidation phase, when drugs called antifolates were the main...

US Professors Develop Fusion Protein to Fight Cancer

...xplains, 'So you can see it would cause a lot less toxicity and it should really be a lot more effective.' The research began with breast cancer and expanded to include other types of solid tumors. Although the fusion protein is helpful in treating many types of cancers, researchers say it works best again...

DNA-damage Test Could Aid Drug Development

...cessful drugs, promising drug candidates must pass toxicity tests before entering clinical trials. Researchers...ell culture test for assessing a compounds genetic toxicity that may prove dramatically cheaper than existing animal tests. This assay would allow genetic toxic...

Gilead's AIDS Drug Awaits Patent in India

...ner drug across Europe for HIV/AIDS due to its low toxicity and resistance levels observed in patients. The tablet-a-day dosage of the drug also helps in better regimen and compliance among the HIV/AIDS patients taking it. Alton also pointed out that he expects generic versions of Gilead's anti-retroviral...

Pazopanib Shows Positive in Advanced Renal Carcinoma, Ovarian Cancer and Soft Tissue Sarcoma

...le complete remissions observed in 7% of patients, toxicity has limited its widespread use. Lower dose cytokine therapies have not shown the same magnitude of response and are also limited by their toxicity. Recently, several anti-angiogenesis drugs, including sunitinib, sorafenib and bevacizumab have demonst...

Amrubicin Shows Encouraging Results for Small Cell Lung Cancer Treatment

... Thirty patients in the trial were evaluable for toxicity and safety, 19 for Amrubicin and 11 for topotecan. The most common . grade 3 adverse events were hematological and were generally equal between the two arms. Cardiac adverse events were limited to tachycardia ( "These results are extremely encouragi...

Breast Cancer Drug Curbs Heart Disease.

...le cells might protect the heart against potential toxicity associated with trastuzumab, Spector added. More broadly, Spector said that these findings of how lapatinib bestows cardiovascular protection during times of stress whether from chemotherapy or heart muscle cells deprived of oxygen during a heart ...

Drugs may Help Turn on Gene Switched Off in Cancer

... who have a high likelihood of response. Their low toxicity means the patient can be treated for long periods of time, which is unlike older and more traditional chemotherapy agents. Even if these new targeted therapies dont cure the cancer, we can at least have long-term survival, he adds....

Researchers Discovers DNA Repair as Key to Huntington's Disease

...acts -- an inherited characteristic -- also caused toxicity in cells that cannot expand, such as nerve cells. The result is that cell death acceleration is directly proportional to the additional repeated lengths. In a further step, the team eliminated a key enzyme (OGG1) related to DNA repair for oxidative...

PFOA and PFOS Detected in Newborns

...ese compounds could cause tumors and developmental toxicity in laboratory animals at doses much higher than those observed in the Hopkins study. The analysis conducted in Baltimore, Md., detected PFOS in 99 percent of the infant samples examined and PFOA in 100 percent of those examined. The results are publ...

1 2 3 4 5 6 7 8

Other Tags
(Date:7/23/2014)... "I wanted a better way to keep track ... sugar, blood pressure and pulse rate," said an inventor from ... carry along a bunch of different devices, so I invented ... Master III to make it easier to monitor health conditions. ... The accessory enables the user to have more control over ...
(Date:7/23/2014)... University researchers discovered an innovative way to reveal ... new treatments for cancer, arthritis, heart disease and ... the mystery of deciphering the contact points where ... another protein like adjacent pieces in a jigsaw ... line to the next protein," says Lance Liotta, ...
(Date:7/23/2014)... According to a new market research report of ... IP, SOC IP), Design Architecture (Hard IP, Soft IP), ... - Forecast & Analysis to 2013 - 2020", the ... a CAGR of 12.6% from 2014 to 2020 and ... 76 market data tables with 60 figures spread through ...
(Date:7/23/2014)... the first time to call for better screening of ... from the condition. , Psoriatic arthritis (PsA) causes painful ... left untreated. , PsA tends to affect people with ... rash, and affects approximately two per cent of people ... go on to develop PsA usually within ten ...
(Date:7/23/2014)... 23, 2014 The Circuelle Foundation ... academic institutions uncovering the importance of breast self-exams ... need for breast self-exams is contradictory and can ... today for keeping this healthy ritual. , “Women ... the significance of breast self-exams and becoming breast ...
Breaking Medicine News(10 mins):Health News:Researchers unlock the protein puzzle 2Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 2Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 3Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 4Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 5Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 6Health News:Psoriatic arthritis patients need better screening, warns panel of experts 2Health News:Historical and Current Research Points to Importance of Breast Self-Exams 2
(Date:7/23/2014)... NH Agricultural Experiment Station are working to restore New ... based on genetic monitoring has found that in the ... become more isolated and seen a 50 percent contraction ... cottontail is now is at risk of becoming extinct ... researchers at the University of New Hampshire College of ...
(Date:7/22/2014)... Arlington computer science and engineering professor with an expertise ... National Science Foundation grant worth more than $600,000 to ... fruit fly., Heng Huang, an associate professor, will lead ... UT Arlington Computer Science and Engineering department. Scientists are ... a large number of genes involved in fruit fly ...
(Date:7/22/2014)... 2014, by lightning from a weather system that moved through ... Stokes Fire, Gold Hikes Fire, French Creek Fire and the ... one larger fire. The fires are burning in timber and ... in size. The present fire situation continues to rapidly ... safety is the priority on the Carlton Complex fires. ...
Breaking Biology News(10 mins):UNH NHAES researchers work to save endangered New England cottontail 2UNH NHAES researchers work to save endangered New England cottontail 3UT Arlington big data team wins $600,000 NSF grant to build gene expression database 2
Other Contents