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Tag: "targets" at medical news

New Gene to Help in Understanding Alzheimer’s Diseas

...pathways to explore the cause as well as potential targets for treatment of this devastating disease." About 4.5 million elderly Americans are currently diagnosed with Alzheimer's, an incurable disease that slowly destroys the patient's brain and always ends in death. The prevalence of the disease ,which ...

A New Strategy to Control Breast Cancer

.... This idea can open up potential new avenues and targets for diagnostic and therapeutic applications. “Because of this, we turned our attention to the processes that regulate the production of the ligands which bind and activate EGFR,” Kenny said. “We reasoned that this binding and activation is essenti...

Bihar to Wipe Out Kalaazar by 2010

The Bihar government targets to turn the state free of kalaazar, a fly-borne fatal parasitic disease that has killed hundreds, by 2010.// The government has formed a special task force, to be headed by former central health minister C.P. Thakur, to battle the disease. Kalaaz...

Eating Spicy Food Daily Could Kill Cancer Cells

... of Nottingham scientists claim that this chemical targets the cancer cells directly. They also say that the medicines that are used in the treatment of psoriasis and muscle strains can be effectively used in the treatment of serious ailments. Dr Timothy Bates who led this study attributes the spicy food e...

Potential Key to Brain Blood-Flow Disorders Explored by Scientists

...is study suggests that these proteins may be novel targets to protect the brain from cerebrovascular disorders. In addition to Nelson, the research team included Jessica Filosa, Ph.D., postdoctoral fellow in pharmacology; Adrian Bonev, Ph.D., research assistant professor of pharmacology; Stephen Straub, Ph.D...

Mother’s Diet During Pregnancy Could Prevent Cancer in Childre

...ing cause, and the fetus and neonate are sensitive targets for toxic carcinogens. It would be important if we could affect this through maternal diet." There are particular concerns about common environmental pollutants called polycyclic aromatic hydrocarbons, or PAHs, which can be produced by cigarette s...

Once-Diabetic Heart/Kidney/Pancreas Transplant Recipient Enjoys Life (And Eating Again)

...t. “He described the heart and the kidneys as the targets of diabetes, and the pancreas as the trigger. Just addressing the target, without eliminating the trigger, would have created a situation that could jeopardize the new organs,” Jim recalls. The first transplants were performed in November 2005. J. ...

Researchers Identify New Drug Targets for Cancer

... suppressor. Their findings could lead to new drug targets for cancer therapies. In a study published in t...y opens up a whole series of potential therapeutic targets for cancer,” said Beth A.A. Weaver, of the Ludwig Institute for Cancer Research and UCSD Department ...

Profiling of Cancer Genes May Lead to Earlier Detection Human Cancers

... early and help identify new promising therapeutic targets to treat some of the most prevalent cancers. “The findings from our study suggest that it may be possible to develop a methylation profiling platform that could be used to screen patients for common solid tumors, while at the same time identify wha...

Italian Who Met Former KBG Spy is Arrested

...ist Anna Politkovskaya and listing other potential targets for assassination. SRI...

Study Offers Window into Human Behavior, Brain Disease

...rior cingulate and frontoinsular cortex -- are key targets of frontotemporal dementia. And in 1999, a team of U.S. scientists made the surprising discovery that, among primates, von Economo neurons were seen only in great apes and humans. In the current study, the UCSF team set out to explore whether von ...

New Line of Antibiotics Could Halve Treatment Time

...perbug MRSA that lives in the nose. The new drug targets bacteria that are left behind by standard antibiotics because the bacteria have developed a resistance to them. The anti-MRSA drug, HT61, is scheduled for testing in humans next year and may be available in the market in five years. Most hospitals...

Unfolded Proteins May Protect Cells from Dying

...t also finding which will make the most attractive targets for pharmacological development.' Source-Newswise...

Genetic Mechanism Helps Explain Chronic Pain Disorders

...clinical pain conditions, as well as provide novel targets for the development of effective individualized therapeutics for TMJD and related conditions," said Dr. Andrea Nackley Neely, a research assistant professor in the Center for Neurosensory Disorders and the study's lead author. "These data have broa...

Gene Therapy for Hereditary Immunodeficiency Diseases

... that carries the gene. Somatic gene transfer only targets body cells (somatic cells). Introducing genes into the germline is illegal in Germany. The first well-documented gene therapy studies were launched in the early 1990s. By 2005 it was estimated that more than 1,100 gene therapy studies had been con...

Cancer Prevention Begins During Pregnancy

...ing cause, and the fetus and neonate are sensitive targets for toxic carcinogens. It would be important if we could affect this through maternal diet." There are particular concerns about common environmental pollutants called polycyclic aromatic hydrocarbons, or PAHs, which can be produced by cigarette sm...

Anti Allergy Drugs Reduce Tumor Growth

...rface. "That way, we could have two potential drug targets - the secreted protein and the receptor," he said. Out of a long list of such genes, Logsdon and his research team selected one called "S100P" because it is a member of the large S100 gene family, some of which produce secreted proteins and some of...

Surprising Interaction Between Genes, Gender, and Hypertension

...tions – which give rise to receptors that might be targets for ACE inhibitors or beta-blockers and other therapies used to treat hypertension – impact blood pressure differently in men and women. Knowing these genetic mutations may help us better diagnose hypertension and select the appropriate therapy,” sai...

Pair of MicroRNA Molecules Controls Major Oncogene in Most Common Leukemia

...ression in cancer development, and could offer new targets for drug treatment, the investigators say. In this case, high levels of two miRNAs known as miR-29 and miR-181 seem to suppress expression of the TCL1 oncogene that drives the most aggressive forms of the leukemia, said the study’s lead author, Yur...

New Drug Offers Promise as Single Treatment for HIV

... the virus' ability to reproduce itself. MK-0518 targets a "third enzyme" called integrase, which is found only in HIV and is essential to the virus' ability to insert its DNA into human genes. By blocking integrase, MK-0518 blocks HIV's ability to reproduce itself and infect new cells. Because it works di...

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