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Tag: "targets" at medical news

A Novel Treatment for KSHV-infected Lymphomas

... A recently discovered strategy for p53 activation targets the interaction of p53 with its negative regulator MDM2. This is based on a potent and selective small-molecule inhibitor of the p53–MDM2 interaction, the Nutlin-3a, originally discovered by Dr Lyubomir T Vassilev (Roche Research Center, Nutley, NJ.,...

New Reason to Hit the Gym: Fighting Memory Loss

...ly what exercise does within the brain//. Exercise targets a region of the brain within the hippocampus, known as the dentate gyrus, which underlies normal age-related memory decline that begins around age 30 for most adults. This finding is significant because it was accomplished via the first-ever observa...

Gene Study Offers Hope of Potent Anti-cancer Drugs

...nt because the more cancer genes we find, the more targets we'll have in terms of potential new drugs." The study, published in the journal Nature, compared the genetic sequence of the DNA derived from a patient's tumor cells with the DNA of healthy cells from the same patient. The aim was to find the muta...

A New Inexpensive Technology for Multiplexed Detection

...ns that turn fluorescent when they detect specific targets in a test sample. Using a new, extremely versatile technique, the researchers can produce a "virtually unlimited" array of particles to test for DNA, RNA, proteins and other biomolecules, said Daniel Pregibon, a graduate student in chemical enginee...

Researchers Discover New Molecular Path to Fight Autoimmune Diseases

...humans because we have a new set of enzymatic drug targets as opposed to the non-specific therapies we now use,” says Greene. Non-specific therapies include the use of steroids and certain chemotherapy-like drugs that act on many cell types and have significant side effects. “Before this work, FOXP3 was th...

MSU Research Strengthens Link Between Smoking, Pancreatic Cancer

...ngs indicated that these stem cells appeared to be targets for cancer. “Since we had the system here in our lab, we decided to see if PAHs would act as a tumor promoter,” he said. “And sure enough they did.” The good news is that people who quit smoking can dramatically improve their chances of avoiding ...

Scientists Identify 120 New Cancer Genes

...nt because the more cancer genes we find, the more targets we'll have in terms of potential new drugs," Stratton was quoted as saying. The researchers in the study compared the genetic sequence of the DNA derived from a patient's tumor cells with the DNA of healthy cells from the same patient in order to fi...

Diminishing Differences and Empowering Eves

...as commodities. Sometimes they are seen as ‘soft’ targets for revenge between feuding individuals or families. This would result in a single woman being serially raped, an act that would churn the stomach of our stone-age ancestor, and raise doubts on the appropriateness of calling us ‘evolved’. Domestic v...

Ovarian Cancer May Mimic Fallopian Tube Formation

...ired box gene 8 gets turned on and to discover its targets in order to find out of it turns on another decision-making gene or an endpoint gene. "That’s the daunting task of cancer biologists,” he said. “Now that we've sequenced the human genome, we have to make sense out of the thousands of genes that are...

J591- an Antibody Exclusively Targets Tumors

...confirms that an antibody called J591 specifically targets an antigen found in high amounts in prostate tumors// and on blood vessels of all solid tumors. Researchers at NewYork-Presbyterian Hospital and Weill Cornell Medical Center conducted this study. Since the prostate-specific membrane antigen (PSMA...

Too Much of Salt in Bread..

...further by 2010. Asda said it would meet the FSA's targets for salt in less than 12 months. "Although our members are happy to be working with the FSA on this issue, the reduction of salt in bread thus far has been immensely challenging as salt plays such a critical role in dough formation," he said. "An...

New Imaging Technique Tracks Traffic Patterns of White Blood Cells

...ances in molecular imaging will likely lead to new targets for the treatment that will improve the life of patients afflicted by this terrible illness.” Source-Newswse SRM...

UAE Introduces Cervical Cancer Vaccine

...ses cancer of the cervix. The new vaccine Gardasil targets the types 6, 11, 16 and 18 of pailloma virus. Of these, HPV type 16 and 18 are responsible for 75% of cases. In the Middle East, UAE is the first nation to have got sanctions for this vaccine from the ministry of health in November 2006. Gadasil ca...

Fetal Heart-Cell Enzyme and Onset of Heart Failure

...re (CHF). The study, which paves the way for new targets for treating cardiac hypertrophy and heart failure...nvolved in cancer. “HDAC and Inpp5f give us new targets for regulating cardiac hypertrophy,” says Epstein. “Inhibitors of HDAC may warrant testing for cardi...

'Gateway' Gene Discovered for Brain Cancer

...r behavior may represent more specific therapeutic targets with little potential to affect off-target cell ty...iption factors are not generally considered useful targets for anti-cancer drugs, there are multiple ways that Olig2 could be inhibited, as well as ways to tar...

Liver an Excellent Target For Cancer Gene Therapy

...rates that cancer cells in the liver are excellent targets for gene therapy using adenoviral vectors//. It is based upon a fundamental new understanding of the differences between cancerous and normal liver cells. The findings signal a new way to treat cancers that have spread to the liver, such as metastati...

First Treatment to Directly Target Tumor Blood Supply

...els of growth signals, but with J591, one directly targets a lethal blow right at the tumor blood supply." As its name implies, PSMA was first spotted in prostate cancers. However, in 1998, Dr. Bander's team found the antigen to be present in the blood vessels of a wide range of tumor types -- but not heal...

New Protein Inhibitor Halts Growth Of Cancerous Cells

...es, these proteins represent potentially important targets for new cancer therapeutics, but few if any effective inhibitors have been identified as acting specifically and effectively against one particular cell-division kinase, known as Plk1. In the new work, Steegmaier et al. isolated a chemical compound...

New Treatment For Psoriasis Is Highly Effective

A new treatment for psoriasis that targets its key inflammatory mediators (IL-12 and IL-23) is highly effective//, according to a study by University of Utah researchers. Current treatments for psoriasis include topical medicines and UV light therapy to treat the symptoms of the disease. M...

Teens More Likely to Become Victims of Online Harassments

...ticle. Approximately 9 percent of online youth are targets of harassment and 13 percent are targets of unwanted sexual solicitation each year. These incidents may lead to psychosocial problems such as...

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