Device That Targets Brain Cancer Shows Promising Results
...ta for an investigational device that specifically targets rapidly growing cancer cells with intermediate frequency electrical fields , called Tumor-Treating Fields (TTFields), has found that it more than doubled the median overall survival rates in patients with the most common and aggressive type of malign...Detecting Cold, Feeling Pain: Study Reveals Why Menthol Fresh
...in recent years by the Julius lab, offer potential targets for developing analgesic drugs that act in the peripheral, nervous system, rather than centrally, where opiate receptors act, he says. The finding is a milestone in an investigation the team began several years ago. In 2002, the researchers discove...Mutant Parasites, Unable to Infect Hosts, Highlight Virulence Genes
...irulence factors" offer a smorgasbord of promising targets for developing drugs that could block or treat human parasitic infections such as malaria. The new results are reported online this week in the Proceedings of the National Academy of Sciences. Though a larger problem in the developing world, parasi...Stop Smoking, Start Living: World No Tobacco Day
...p quit smoking. The drug, Champix (Varenicline) targets the nicotinic receptor in a unique way to reduce the intensity of the smokers craving and also the severity of the withdrawal symptoms. The drug marketed by Pfizer is expected to do wonders in this area. There is substantial evidence to demand im...Investigational Drug Being Pursued for the Treatment of Ischaemic Stroke
...ole in influencing stroke outcome. Ancrod directly targets fibrinogen and has the potential to treat strokes by rapidly lowering fibrinogen levels," said David E. Levy, MD, Vice President of Clinical Development for NTI. "We are aggressively recruiting patients worldwide for the ASP-I and ASP-II studies. W...Step-Based Guidelines in New Pair of Studies
...lth benefits. For inactive people, setting smaller targets can help them start a program to meet general physical activity guidelines and enhance their health and wellness." In the one-mile study, researchers at Boise State University wanted to determine the number of steps individuals take while walking o...G8 Members To Announce Plans To Increase HIV/AIDS Spending at Summit
...multiyear funding based on ambitious but realistic targets is made available" to the Global Fund to Fight AIDS, Tuberculosis and Malaria. In addition, G8 leaders said they plan to reaffirm their pledges to support African countries in their efforts to reach the U.N. Millennium Development Goals. UNAIDS est...Bush Isolated on Climate Change Heading into G8
...tiators fought to remove any references to binding targets from the summit's 22-page draft statement on global warming. Bush argued that each nation should set its own goals for cutting emissions of heat-trapping gases - mostly carbon dioxide from the burning of fossil fuels - that are blamed for global warm...New Findings in Fragile X Mental Retardation Protein
... its targets. She said, We expect to identify more targets which are regulated by FMRP and NXF2. This will be a new direction in the FMRP research field....Rescheduled: Aerial Mosquito Treatment for Philadelphia
...de, but is a species-specific bacterial agent that targets mosquito and black fly larvae when added to the water in production areas -- will only be applied in areas where sampling has shown increased levels of mosquitoes. Beginning around 8 a.m. Thursday, Helicopter Applicators Inc., of Gettysburg, Adams ...Scientists Spotted Out Tumor Vessel by Molecular Markers
...ncode cell surface proteins, making them appealing targets for the development of new therapeutic agents. O...,' explained Dr. St. Croix; 'they also provide new targets that could help guide the development of safer vascular-targeted therapies with potentially fewer si...Drugs may Help Turn on Gene Switched Off in Cancer
...ls, they insist that their finding may lead to new targets for cancer treatment. This is a targetable target. We can detect it, but we need to find a better way to turn it back on. No drugs are designed to deal with a gene thats turned off. But its a straightforward extension of current therapies that targ...Landmark Study Prompts Rethink of Genetic Code
...borative study focussed on 44 strategically chosen targets which together account for about one percent of the genome, or about 30 million of the three billion "rungs" in the DNA double-helix ladder. The data is being placed in the public domain to help medical and other research....UK Scientists to Undertake Seven Year Study of Peanut Allergy
... enable scientists to identify important treatment targets to try and develop cures for children who already suffer from peanut allergy." GPL/B...Gene Responsible for Ageing Process Discovered – and Calorie Restriction Could Hel
...enetic treasure-chest of potential pharmacological targets for developing drugs that can extend the human lifespan without having to follow a rigorous and difficult diet. The first experiments in calorie-restricted diets go back to the 1930s. Laboratory rats and mice fed a severely calorie-restricted diet,...New Agent to Fight Genetic Disorders Found
...among others. "Zorro-LNA is a new substance that targets DNA and turns off genes," said co-author Edvard Smith of the Karolinska Institute in Sweden. "It has the potential of becoming a new drug for the treatment of human genetic disease." The findings described in this article significantly raise the po...Correlation Between Bile Duct Obstruction and Ductal Cancer Found
...of the cancer and that could become good molecular targets for drug therapy. Second, they establish a unique preclinical model of how bile duct cancer in liver progresses that can be used to rapidly test and evaluate novel molecular treatment strategies. Such strategies are badly needed for this underst...Researchers Identify New Genetic Risk Factors for Type 2 Diabetes
...may point us in the direction of valuable new drug targets for the prevention or treatment of type 2 diabetes." Previously known as adult onset or non-insulin dependent diabetes (NIDDM), type 2 diabetes usually appears after age 40, often in overweight, sedentary individuals. However, an increasing number ...Hospitals Make Positive Strides to Reduce Wait Times for Patients
...r patients in Canada’s hospitals has improved, but targets for some emergency procedures still needs improvement, according to the report// released by Wait Time Alliance of the Canadian Medical Association. The report also stresses the importance of timely information to patients about exact treatment times......well.” Rituximab is an antibody-based drug that targets CLL and ALL cells and causes the cells to self-destruct. “We've shown that knocking down Mcl1 can, by itself, cause CLL cells to die, and that this effect might enhance the activity of rituximab,” says first author Rehan Hussain, a postdoctoral fe...