Boffins Identify Gene That can Protect Humans from Nephronopthisis
...ve already identified one promising candidate drug target and our mouse model will help us find many others," he added. The study is available in the current online issue of Nature Genetics....Malawi Targets 150,000 People With AIDS Drugs
Malawi has set itself a target of supplying 150,000 HIV sufferers with free anti-retroviral drugs by the end of year, the head of the national AIDS commission (NAC) said on Monday . "We are close to 110,000 people on ARVs and we hope to hit 150,000 by the end of December when we...New Therapies for Kidney Diseases
...ve already identified one promising candidate drug target and our mouse model will help us find many others....Radical Change in the Lifestyle Might Bring a Greener Future for Brits
...ing the atmosphere. The UK government has set a target of cutting 60 per cent of carbon emissions by 2050, which is higher than many other countries. But the CAT believes this is not enough. In its report, the CAT suggests creating a market for carbon that affects every individual, household and compa...Gene Therapy Eradicates Pancreatic Cancer in Mice
..., two components that boost gene expression in the target tissue, and a payload that is a gene known to kill cancer cells in this case. All these are packaged in a fatty ball called liposome, and delivered through veins. "This looks like a promising approach to gene therapy for pancreatic cancer and w...Brits Need to Change Lifestyle to Have a Greener Future: Report
...ing the atmosphere. The UK government has set a target of cutting 60 per cent of carbon emissions by 2050, which is higher than many other countries. But the CAT believes this is not enough. In its report, the CAT suggests creating a market for carbon that affects every individual, household and compa...Parkinson's Targets Two Distinct Brain Networks, Finds Study
...ng to alter these networks and we need new ones to target these symptoms," Dr. Eidelberg said. Eidelberg added that the networks could be used as biomarkers to diagnose the disease. The scientists have also developed mathematical computer models to determine how fast the disease will progress. "These s...New Cancer Therapy in Clinical Trial
...eath receptor signaling an attractive and exciting target for cancer therapy, and it is currently being tested in clinical trials. However, most cancer cells have defects in their ability to die via a cell death pathway called apoptosis, and unfortunately, TRAIL therapy is not effective in cells that have...Smokers may Develop Chronic Obstructive Pulmonary Disease
...ole of IL-13 in COPD, the protein may one day be a target for new drugs for the disease. The variant has been shown to be associated with asthma, which may help explain why COPD and asthma tend to cluster in families, Ohar said. Media Contacts: Karen Richardson, krchrdsn@wfubmc.edu; Shannon Koontz, shkoo...Newborn Screening Tests for Babies
...ements. The snapshot shows that the nation is on target to meet the March of Dimes goal of having all babies screened for 20 or more of the recommended panel of genetic disorders by 2008....Cell Toxin Inhibits Survival Protein in Cancer Cells
...express Bcl-2 proteins. Higher expression of the target protein made cells more sensitive to the 2-Methoxy antimycin inhibitor. This is called a gain of function mechanism and is counterintuitive to the way most drugs work. Our compound, 2-Methoxy antimycin, is the only Bcl-2 inhibitor reported with gai...Hospital Infection Affecting Patients in Scotland
...ramme for those going into hospital. It would also target skin and soft tissue infections, reducing blood stream infections and would try and use additional data to tackle infection rates in medical and elderly wards. The survey found almost all of the infections of the super bug clostridium difficile were...Tobacco Industry Promotes Antismoking Campaigns
...tising in light of successful media campaigns that target large audiences. From 1975 to 2003, tobacco indu...s pink cigarettes that public health advocates say target teenage girls not women. In June, congress sent a letter to the editors of 11 major magazines, from ...A New Monoclonal Antibody Kills Cancer Cells
...at PDGFR alpha offers an important new therapeutic target for the treatment of HCC. We are very excited because this is the first targeted therapy for liver cancer. Other therapies have some modest benefits, but no one knows exactly how they work. We now have identified a pathway that appears to be ove...Monoclonal Antibody Induces Death in Liver Cancer Cells
...esults depict PDGFRa as a possible new therapeutic target for the treatment of HCC. "We are very excited because this is the first targeted therapy for liver cancer. Other therapies have some modest benefits, but no one knows exactly how they work. We now have identified a pathway that appears to be over...Genetic Variation in Some Smokers Increases Chances of Developing COPD
... of IL-13 in COPD, the protein may eventually be a target for new drugs for the disease. The variant has been shown to be associated with asthma, which may help explain why COPD and asthma tend to cluster in families, Ohar said. The study is published online and will appear in a future print issue of th...Trial of VivaGel in Sexually Active Young Women Commences
...be used in sexually active young women, one of our target populations. This study, in addition to the usual safety data, will collect valuable information regarding the product's use and acceptability in the consumer setting," said Dr Jackie Fairley, Chief Executive Officer of Starpharma. "The data from t...All Babies in Massachusetts Should Be Screened for Life-Threatening Disorders
...ements. The snapshot shows that the nation is on target to meet the March of Dimes goal of having all babies screened for 20 or more of the recommended panel of genetic disorders by 2008....Modified Herpes Virus Keeps Arteries Free-flowing Following Procedures
...p treated with the herpes virus. The ability to target the smooth muscle cells that cause the narrowing, and regenerate the endothelial cell lining is an important finding, noted Skelly. This study is an important step in the application of genetically engineered herpes simplex viruses for treatment o...Sciton Receives FDA Clearance for Lipolysis and Wrinkle Treatment
...m Sciton to employ fiber-delivered laser energy to target fatty tissue. Using the ProLipo module, physicians will be able to offer patients a minimally invasive treatment that ablates and liquefies fat deposits in treated areas. ProLipo will ideally be used in combination therapy with other proprietary trea...